TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Products of "TRP/TRPV Channel"
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MK-2295
CAS:MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.Formula:C27H31FN6O2Purity:98.1% - 98.83%Color and Shape:SolidMolecular weight:490.57SET 2
CAS:SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.Formula:C17H21F3N4O2SPurity:98.43%Color and Shape:SolidMolecular weight:402.43Ref: TM-T37097
5mg58.00€10mg96.00€25mg177.00€50mg300.00€100mg437.00€500mgTo inquire1mL*10mM (DMSO)71.00€SB 452533
CAS:SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Formula:C18H22BrN3OPurity:98.52%Color and Shape:SolidMolecular weight:376.29Ref: TM-T23322
2mg42.00€5mg64.00€10mg97.00€25mg183.00€50mg284.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)85.00€Pyr6
CAS:Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influxFormula:C17H9F7N4OPurity:98.89%Color and Shape:SolidMolecular weight:418.27ICILIN
CAS:ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.Formula:C16H13N3O4Purity:97.61% - ≥95%Color and Shape:Light Yellow SolidMolecular weight:311.29ML-SI3
CAS:CCG-143140 is a GLP-1 receptor inverse agonists.Formula:C23H31N3O3SPurity:99.75%Color and Shape:SolidMolecular weight:429.58Fingolimod hydrochloride
CAS:Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).Formula:C19H34ClNO2Purity:99.26% - 99.83%Color and Shape:White SolidMolecular weight:343.93CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.Color and Shape:Odour SolidEvifacotrep
CAS:Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).Formula:C18H12ClF4N5O2Purity:98.6%Color and Shape:SolidMolecular weight:441.77Ref: TM-T40042
1mg96.00€5mg188.00€10mg303.00€25mg465.00€50mg692.00€100mg1,026.00€200mg1,549.00€1mL*10mM (DMSO)160.00€AM-0902
CAS:AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).Formula:C17H15ClN6O2Purity:100%Color and Shape:SolidMolecular weight:370.79SN 2
CAS:SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN 2 also shares a similar antiviral effect against DENV2 and ZIKV.Formula:C17H21NOPurity:99.20%Color and Shape:SolidMolecular weight:255.35Ref: TM-T12941
5mg52.00€10mg75.00€25mg149.00€50mg283.00€100mg415.00€200mg582.00€1mL*10mM (DMSO)52.00€Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Formula:C26H43NO3Purity:95.06%Color and Shape:SolidMolecular weight:417.62GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Formula:C22H25N3O2SPurity:98.15%Color and Shape:SolidMolecular weight:395.529-Phenanthrol
CAS:9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Formula:C14H10OPurity:98.72%Color and Shape:SolidMolecular weight:194.23Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Formula:C19H23N5O3Purity:99.97%Color and Shape:SolidMolecular weight:369.42TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formula:C25H23ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:484.93TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purity:≥98.0%Color and Shape:SolidMolecular weight:338.32JC-229
CAS:JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).Formula:C20H14Cl4N2O3SPurity:97.14%Color and Shape:SolidMolecular weight:504.21AMG2850
CAS:AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Formula:C19H17F6N3OPurity:99.05%Color and Shape:SolidMolecular weight:417.35Ref: TM-T10300
1mg74.00€5mg170.00€10mg248.00€25mg445.00€50mg662.00€100mg848.00€1mL*10mM (DMSO)182.00€TC-I2000
CAS:TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Formula:C23H18F4N2OPurity:98.87%Color and Shape:SolidMolecular weight:414.4
