TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Products of "TRP/TRPV Channel"
Sort by
PF-05105679
CAS:PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.Formula:C26H21FN2O3Purity:99.82%Color and Shape:SolidMolecular weight:428.45Ref: TM-T16483
1mg48.00€2mg65.00€5mg96.00€10mg160.00€25mg305.00€50mg472.00€100mg710.00€200mg938.00€500mg1,444.00€1mL*10mM (DMSO)96.00€Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Formula:C18H13F6N3O2SPurity:99.69% - 99.70%Color and Shape:SolidMolecular weight:449.37IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formula:C8H12INOPurity:99.76%Color and Shape:SolidMolecular weight:265.09Ref: TM-T15543
1mg59.00€5mg126.00€10mg187.00€25mg264.00€50mg329.00€100mg455.00€1mL*10mM (DMSO)120.00€TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Formula:C22H21NO4Purity:98.16%Color and Shape:SolidMolecular weight:363.41Pyr3
CAS:Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Formula:C16H11Cl3F3N3O3Purity:99.47%Color and Shape:SolidMolecular weight:456.63Ref: TM-T16687
1mg35.00€2mg52.00€5mg77.00€10mg97.00€25mg215.00€50mg363.00€100mg512.00€200mg738.00€500mg1,121.00€1mL*10mM (DMSO)86.00€RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Formula:C14H22Cl2N2O2SPurity:99.1% - 99.30%Color and Shape:SolidMolecular weight:353.31SB-366791
CAS:SB-366791 is a new and selective cinnamide TRPV1 antagonist.Formula:C16H14ClNO2Purity:99.12%Color and Shape:SolidMolecular weight:287.74TRPM8 antagonist 2
CAS:TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Formula:C26H26N2O2Purity:98.10%Color and Shape:SolidMolecular weight:398.5Ref: TM-T5698
1mg35.00€5mg70.00€10mg104.00€25mg170.00€50mg274.00€100mg439.00€200mg632.00€1mL*10mM (DMSO)78.00€NGD-8243
CAS:NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFormula:C21H12F6N4Purity:95.26%Color and Shape:SolidMolecular weight:434.34Vocacapsaicin hydrochloride
CAS:Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Formula:C26H42ClN3O4Purity:98.51% - 99.94%Color and Shape:SolidMolecular weight:496.08HC-067047
CAS:HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .Formula:C26H28F3N3O2Purity:99.45% - 99.79%Color and Shape:SolidMolecular weight:471.51SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Formula:C21H22ClN3OPurity:99.62% - 99.71%Color and Shape:SolidMolecular weight:367.87Ref: TM-T12849
1mg71.00€5mg160.00€10mg250.00€25mg401.00€50mg567.00€100mg707.00€200mg938.00€1mL*10mM (DMSO)170.00€Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Formula:C21H22F5N3O3SPurity:95.13%Color and Shape:SolidMolecular weight:491.48WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Formula:C18H27NO2Purity:99.99%Color and Shape:Whitish To White Solid CrystallineMolecular weight:289.41ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Formula:C22H22N2OPurity:100%Color and Shape:SolidMolecular weight:330.42Ref: TM-T14087
1mg48.00€5mg96.00€10mg160.00€25mg313.00€50mg470.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)96.00€JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Formula:C19H21F3N2O2Purity:98.57%Color and Shape:SolidMolecular weight:366.38Ref: TM-T74779
1mg92.00€5mg215.00€10mg321.00€25mg494.00€50mg856.00€100mg1,478.00€200mg1,931.00€1mL*10mM (DMSO)225.00€PF-04745637
CAS:PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Formula:C27H32ClF3N2O2Purity:97.91% - 99.3%Color and Shape:SolidMolecular weight:509Ref: TM-T64337
1mg73.00€5mg145.00€10mg197.00€25mg333.00€50mg475.00€100mg655.00€200mg882.00€1mL*10mM (DMSO)163.00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Formula:C16H19NO3SPurity:99.46%Color and Shape:SolidMolecular weight:305.39Ref: TM-T28118
2mg34.00€5mg52.00€10mg85.00€25mg170.00€50mg255.00€100mg378.00€200mg533.00€1mL*10mM (DMSO)74.00€M084
CAS:M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.Formula:C11H15N3Purity:98.13%Color and Shape:SolidMolecular weight:189.26Ref: TM-T8607
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)145.00€MDR-652
CAS:MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFormula:C22H23ClFN3O2SPurity:99.96%Color and Shape:SolidMolecular weight:447.95Ref: TM-T22360
1mg66.00€5mg144.00€10mg205.00€25mg369.00€50mg558.00€100mg800.00€200mg1,074.00€1mL*10mM (DMSO)157.00€
