Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Products of "Potassium Channel"
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Miconazole
CAS:Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.Formula:C18H14Cl4N2OPurity:100% - 99.78%Color and Shape:SolidMolecular weight:416.13Prazosin hydrochloride
CAS:Prazosin HCl, a synthetic antiadrenergic, treats hypertension, heart failure, and more by relaxing blood vessels with an unclear mechanism.Formula:C19H22ClN5O4Purity:99.87% - 99.89%Color and Shape:White To Tan Powder Off-White To Yellow PowderMolecular weight:419.86Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.Formula:C14H12N6OPurity:99.32% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81ICA 110381
CAS:ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Aprikalim
CAS:Aprikalim opens KATP channels, protects the heart, and at high doses, dilates blood vessels.Formula:C12H16N2OS2Purity:99.28% - 99.38%Color and Shape:SolidMolecular weight:268.4Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:Crystal PowderMolecular weight:435.31Pinacidil monohydrate
CAS:Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Formula:C13H21N5OPurity:99.94% - 99.96%Color and Shape:PowderMolecular weight:263.34Cromakalim
CAS:Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33KV1.3-IN-2
CAS:KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818Guanfu base A
CAS:Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.Formula:C24H31NO6Purity:99.71% - 99.85%Color and Shape:SolidMolecular weight:429.5ZM 226600
CAS:ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.Formula:C16H14F3NO4SPurity:100%Color and Shape:SolidMolecular weight:373.35Ref: TM-T23563
2mg35.00€5mg50.00€10mg80.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)55.00€P-1075
CAS:P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.Formula:C12H17N5Purity:99.35%Color and Shape:SolidMolecular weight:231.3Ref: TM-T16420
1mg60.00€2mg88.00€5mg126.00€10mg202.00€25mg374.00€50mg560.00€100mg800.00€500mg1,644.00€1mL*10mM (DMSO)96.00€Rosuvastatin calcium
CAS:Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormula:(C22H27FN3O6S)CaPurity:98.85% - 99.68%Color and Shape:White To Off-White Crystalline SolidMolecular weight:1001.14Oxybutynin chloride
CAS:Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.Formula:C22H32ClNO3Purity:98.71% - 99.17%Color and Shape:White PowderMolecular weight:393.96Diazoxide
CAS:Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formula:C8H7ClN2O2SPurity:99% - 99.83%Color and Shape:SolidMolecular weight:230.67Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purity:97.11% - 99.23%Color and Shape:Lactic AcidosisMolecular weight:241.72Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purity:98.25% - 99.95%Color and Shape:Colorless Crystals From Ethanol + Ether White Crystalline PowderMolecular weight:512.33Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Tipepidine hydrochloride
CAS:Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Formula:C15H18ClNS2Purity:99.97%Color and Shape:SolidMolecular weight:311.89(±)-Naringenin
CAS:(±)-Naringenin (Naringenine) is a natural product.Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25ML277
CAS:ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59Rimtuzalcap
CAS:Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formula:C18H24F2N6OPurity:99.54%Color and Shape:SolidMolecular weight:378.42Ref: TM-T9522
1mg35.00€5mg78.00€10mg111.00€25mg215.00€50mg320.00€100mg452.00€200mg632.00€1mL*10mM (DMSO)34.00€BSH-IN-1
CAS:BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B.Formula:C25H41FO3Purity:98%Color and Shape:SolidMolecular weight:408.59Ref: TM-T10623
1mg116.00€5mg283.00€10mg445.00€25mg738.00€50mg1,017.00€100mg1,415.00€1mL*10mM (DMSO)310.00€Budiodarone tartrate
CAS:Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.Formula:C31H37I2NO11Purity:97.44%Color and Shape:SolidMolecular weight:853.44Gliclazide
CAS:Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of theFormula:C15H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:323.41LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82E-4031
CAS:E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44KCNQ1 activator-1
CAS:N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57H3B-120
CAS:H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.Formula:C19H24N4O2SPurity:99.03% - 99.2%Color and Shape:SolidMolecular weight:372.48Ref: TM-T11529
1mg113.00€5mg235.00€10mg393.00€25mg657.00€50mg935.00€100mg1,264.00€500mg2,527.00€1mL*10mM (DMSO)259.00€(+)-KCC2 blocker 1
CAS:(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).Formula:C22H25NO5SPurity:98.12%Color and Shape:SolidMolecular weight:415.5Ref: TM-T12504
1mg115.00€2mg172.00€5mg255.00€10mg374.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,147.00€1mL*10mM (DMSO)284.00€5-Hydroxydecanoate sodium
CAS:5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.Formula:C10H19NaO3Purity:≥98%Color and Shape:SolidMolecular weight:210.25HUP30
CAS:HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.Formula:C14H15N3O3SPurity:99.8%Color and Shape:SolidMolecular weight:305.35Ref: TM-TNU0864
2mg35.00€5mg50.00€10mg80.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)55.00€Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:SolidMolecular weight:353.81JNJ-26489112
CAS:JNJ-26489112 is a CNS-active agent and an inhibitor of voltage-gated Na+ channels and N-type Ca2+ channels.Formula:C9H11ClN2O4SPurity:99.31%Color and Shape:SolidMolecular weight:278.71Ifenprodil Tartrate
CAS:Ifenprodil is a selective NMDA receptor (glutamate) antagonist.Formula:C21H27NO2C4H6O6Purity:99.02% - 99.55%Color and Shape:SolidMolecular weight:400.49Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormula:C31H32N4O2Purity:98.90%Color and Shape:SolidMolecular weight:492.61Kv7.2/Kv7.3 agonist 1
CAS:Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.Formula:C14H14FN3O2Color and Shape:SolidMolecular weight:275.28MK-0448
CAS:MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.Formula:C24H21FN4O2SPurity:99.25% - 99.79%Color and Shape:SolidMolecular weight:448.51Vernakalant Hydrochloride
CAS:Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.Formula:C20H32ClNO4Purity:99.04%Color and Shape:SolidMolecular weight:385.93Ref: TM-T17227
1mg74.00€2mg97.00€5mg170.00€10mg274.00€25mg523.00€50mg753.00€100mg1,035.00€1mL*10mM (DMSO)187.00€Tannic acid
CAS:Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Formula:C76H52O46Purity:AR - ARColor and Shape:Light Yellow To Light Brown Solid Solid Particulate/PowderMolecular weight:1701.2Doxapram hydrochloride hydrate
CAS:Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.Formula:C24H33ClN2O3C24H30N2O2·ClH·H2OPurity:100% - 99.64%Color and Shape:SolidMolecular weight:432.99Acetohexamide
CAS:Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity.Formula:C15H20N2O4SPurity:99.19% - 99.85%Color and Shape:Crystals From 90% Aq EthanolMolecular weight:324.4NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99%Color and Shape:SolidMolecular weight:380.24Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formula:C33H40N2O9Purity:98.85% - 99.81%Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Molecular weight:608.68GAL-021
CAS:GAL-021 an intravenous BKCa-channel blocker.Formula:C11H22N6OPurity:97.71% - 99.73%Color and Shape:SolidMolecular weight:254.33Ref: TM-T3557
1mg37.00€5mg74.00€10mg103.00€25mg187.00€50mg283.00€100mg437.00€500mg938.00€1mL*10mM (DMSO)85.00€Proflavine Hemisulfate
CAS:Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formula:C13H12N3O2S0Purity:99.55%Color and Shape:Orange To Red PowderMolecular weight:258.29KNa1.1-IN-2
CAS:KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48
