Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Products of "Potassium Channel"
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NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23Ref: TM-T3102
1mg37.00€2mg52.00€5mg79.00€10mg97.00€25mg170.00€50mg253.00€100mg376.00€1mL*10mM (DMSO)87.00€Guanosine 5'-diphosphate
CAS:Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.Formula:C10H15N5O11P2Purity:100% - 98.46%Color and Shape:SolidMolecular weight:443.2ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purity:97.29%Color and Shape:SolidMolecular weight:388.4Ref: TM-T9070
1mg35.00€2mg48.00€5mg70.00€10mg96.00€25mg188.00€50mg311.00€100mg512.00€1mL*10mM (DMSO)77.00€Branaplam
CAS:Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.Formula:C22H27N5O2Purity:97.81% - 99.73%Color and Shape:SolidMolecular weight:393.48Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:98.45% - 99.51%Color and Shape:SoildMolecular weight:532.5239-Hydroxycanthin-6-one
CAS:9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E.Formula:C14H8N2O2Purity:98%Color and Shape:SolidMolecular weight:236.23Endoxifen Z-isomer hydrochloride
CAS:Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.Formula:C25H28ClNO2Color and Shape:SolidMolecular weight:409.95Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formula:(C20H36N2O3S)2·C4H4O4Purity:99.68% - 99.74%Color and Shape:SolidMolecular weight:885.23Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purity:100% - 99.89%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94Nicorandil
CAS:Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.Formula:C8H9N3O4Purity:98.14% - 99.44%Color and Shape:White Or Off-White PowderMolecular weight:211.17Sipatrigine
CAS:Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.Formula:C15H16Cl3N5Purity:100% - 99.49%Color and Shape:SolidMolecular weight:372.68Ref: TM-T16887
1mg96.00€5mg202.00€10mg303.00€25mg507.00€50mg730.00€100mg1,026.00€200mg1,378.00€1mL*10mM (DMSO)224.00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.92%Color and Shape:Light Yellow PowderMolecular weight:610.74TWIK-1/TREK-1-IN-3
CAS:TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.Formula:C19H27F3N2O2Purity:99.04%Color and Shape:SolidMolecular weight:372.43Alismol
CAS:Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used forFormula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35Mesoridazine Besylate
CAS:Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Formula:C27H32N2O4S3Purity:99.58%Color and Shape:SolidMolecular weight:544.75KCC2 Modulator-2
CAS:KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.Formula:C35H45N5O3Color and Shape:SolidMolecular weight:583.76Minoxidil
CAS:Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.Formula:C9H15N5OPurity:99.89% - 99.97%Color and Shape:Crystals From Methanol-Acetonitrile SolidMolecular weight:209.25Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56Atpenin A5
CAS:Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24Pimozide
CAS:Pimozide: antipsychotic that blocks type 2 dopamine, alpha-adrenergic, and 5-HT2 receptors, reducing tics and delusions.Formula:C28H29F2N3OPurity:100% - 99.85%Color and Shape:SolidMolecular weight:461.55QO-40
CAS:QO-40 is a KCNQ2/3 potassium channels activator.Formula:C18H11ClF3N3OPurity:99.57%Color and Shape:SolidMolecular weight:377.75Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formula:C18H19N3O4Purity:99.80%Color and Shape:SolidMolecular weight:341.36Kv2-IN-A1
CAS:Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.Formula:C20H17ClN4OSPurity:98.83%Color and Shape:SolidMolecular weight:396.89Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.8%Color and Shape:SolidMolecular weight:481.544-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:90%Color and Shape:SolidMolecular weight:94.11SKA-31
CAS:SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26BMS-191011
CAS:BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormula:C16H10ClF3N2O3Purity:97.43%Color and Shape:SolidMolecular weight:370.71Ebio3
Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Oxypeucedanin
CAS:1.Formula:C16H14O5Purity:98.66% - 98.85%Color and Shape:SolidMolecular weight:286.28Chlorahololide C
CAS:Chlorahololide C blocks potassium channels, selectively inhibiting I(K) current with an IC50 of 3.6±10.1 µM.Formula:C33H36O9Purity:98%Color and Shape:SolidMolecular weight:576.63VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFormula:C20H22ClFN4O2SPurity:97.91%Color and Shape:SoildMolecular weight:436.93Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Flindokalner
CAS:Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formula:C16H10ClF4NO2Purity:99.25%Color and Shape:SolidMolecular weight:359.7Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Formula:C22H31NO3Purity:100% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49MCHR1 antagonist 2
CAS:MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.Formula:C23H21FN2O5Purity:97.16%Color and Shape:SolidMolecular weight:424.42Ref: TM-T11966
1mg49.00€5mg104.00€10mg170.00€25mg369.00€50mg588.00€100mg944.00€1mL*10mM (DMSO)126.00€XE 991 dihydrochloride
CAS:XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Ref: TM-T16347
2mg34.00€5mg52.00€10mg85.00€25mg156.00€50mg245.00€100mg364.00€200mg517.00€1mL*10mM (DMSO)58.00€Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Ref: TM-T8125
5mg44.00€10mg55.00€25mg78.00€50mg99.00€100mg150.00€200mg219.00€500mg366.00€1mL*10mM (DMSO)65.00€Quinine
CAS:Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23VU591
CAS:1222810-74-3Formula:C16H12N6O5Purity:99.29% - 99.53%Color and Shape:SolidMolecular weight:368.3TRAM-34
CAS:TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.Formula:C22H17ClN2Purity:99.01% - 99.76%Color and Shape:SolidMolecular weight:344.8420(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:100% - 99.93%Color and Shape:SolidMolecular weight:785.01XE991
CAS:XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.Formula:C26H20N2OPurity:99.51%Color and Shape:SolidMolecular weight:376.45Ref: TM-T78570
1mg48.00€5mg96.00€10mg153.00€25mg283.00€50mg522.00€100mg838.00€500mg1,681.00€1mL*10mM (DMSO)105.00€Astemizole
CAS:Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Formula:C28H31FN4OPurity:98.24% - 99.67%Color and Shape:White Crystals SolidMolecular weight:458.57
