
Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Products of "Potassium Channel"
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1-EBIO
CAS:1-EBIO (1-EBIO) is a calium channel agonist.Formula:C9H10N2OPurity:99.79%Color and Shape:SolidMolecular weight:162.19Linopirdine
CAS:Linopirdine (DuP 996) is a TRPV1 agonist.Formula:C26H21N3OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:391.46Ref: TM-T15758
1mg43.00€2mg56.00€5mg88.00€10mg126.00€25mg227.00€50mg393.00€100mg560.00€200mg810.00€500mg1,206.00€1mL*10mM (DMSO)87.00€Amsacrine
CAS:Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.Formula:C21H19N3O3SPurity:98.59%Color and Shape:Yellow Crystalline Powder SolidMolecular weight:393.46Amifampridine
CAS:Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.Formula:C5H7N3Purity:99.82%Color and Shape:Slightly Beige PowderMolecular weight:109.13Hydroquinidine
CAS:Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.Formula:C20H26N2O2Purity:98.61% - 99.68%Color and Shape:SolidMolecular weight:326.43Clobutinol hydrochloride
CAS:Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].Formula:C14H23Cl2NOPurity:98%Color and Shape:SolidMolecular weight:292.25Gut restricted-7
CAS:Gut restricted-7 (GR-7) (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor.Formula:C25H40FNaO6SPurity:98.81% - 99.27%Color and Shape:SolidMolecular weight:510.64Quinine hydrochloride dihydrate
CAS:Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.Formula:C20H24N2O2·HCl·2H2OPurity:99.04%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.91TWIK-1/TREK-1-IN-2
CAS:TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 valuesFormula:C20H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:386.45Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.74%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurity:99.97%Color and Shape:SolidMolecular weight:378.31Ref: TM-T0860L
1mg70.00€5mg154.00€10mg225.00€25mg376.00€50mg538.00€100mg755.00€200mg1,017.00€1mL*10mM (DMSO)160.00€RU-TRAAK-2
CAS:RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.Formula:C19H17N3OSPurity:99.68%Color and Shape:SolidMolecular weight:335.42Ref: TM-T60061
1mg81.00€5mg170.00€10mg264.00€25mg454.00€50mg620.00€100mg873.00€200mg1,169.00€1mL*10mM (DMSO)180.00€Nigericin sodium salt
CAS:Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.Formula:C40H67NaO11Purity:98.2% - 99.52%Color and Shape:SolidMolecular weight:746.94AM-92016 hydrochloride
CAS:AM-92016 is a specific blocker of rectifier potassium current.Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84Ref: TM-T5585
2mg35.00€5mg52.00€10mg96.00€25mg164.00€50mg279.00€100mg399.00€200mg567.00€1mL*10mM (DMSO)58.00€Celivarone
CAS:Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.Formula:C34H47NO4Purity:99.03%Color and Shape:SolidMolecular weight:533.74Azimilide Dihydrochloride
CAS:Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.Formula:C23H30Cl3N5O3Purity:97.59% - ≥95%Color and Shape:SolidMolecular weight:530.88Hydroxyhexamide
CAS:Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.Formula:C15H22N2O4SPurity:98.91%Color and Shape:SolidMolecular weight:326.41ML365
CAS:ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).Formula:C22H20N2O3Purity:98.78%Color and Shape:SolidMolecular weight:360.41cis-KV1.3-IN-1
CAS:cis-KV1.3-IN-1, also known as Compound cis-18, is the cis-isomer of KV1.3-IN-1 and functions as an inhibitor of the KV1.3 channel. In Xenopus laevis oocytes expressing human hKV1.3, cis-KV1.3-IN-1 (10 μM) achieves an inhibition rate of 25.53% against KV1.3.Formula:C23H30N2O4SColor and Shape:SolidMolecular weight:430.56Allocryptopine
CAS:Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.Formula:C21H23NO5Purity:99.23% - ≥95%Color and Shape:SolidMolecular weight:369.41ADWX 1 TFA
ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.Formula:C169H281N57O46S7·xC2HF3O2Color and Shape:SolidMolecular weight:4071.85 (free base)Vernakalant
CAS:Vernakalant (RSD-1235) is a mixed ion channel blocker.Formula:C20H31NO4Purity:98%Color and Shape:SolidMolecular weight:349.46