Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Products of "Calcium Channel"
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HA-1004 dihydrochloride
CAS:HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel proteinFormula:C12H16ClN5O2SPurity:98%Color and Shape:White Crystalline SolidMolecular weight:329.81Verapamil hydrochloride
CAS:Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.Formula:C27H39ClN2O4Purity:98.7% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:491.061,1-Dicinnamylpiperazin-1-ium Cinnarizine Chloride
Controlled ProductFormula:C35H37ClN2Color and Shape:NeatMolecular weight:521.13Penfluridol
CAS:Penfluridol (TLP-607) is a highly potent antipsychotic.Formula:C28H27ClF5NOPurity:98.9% - 99.73%Color and Shape:Off-White To White Crystalline PowderMolecular weight:523.97Upacicalcet
CAS:Upacicalcet (AJT-240) is a calcium mimetic for SHPT in dialysis, reducing PTH by targeting parathyroid receptors.Formula:C11H14ClN3O6SPurity:98.57%Color and Shape:SolidMolecular weight:351.76Gabapentin hydrochloride
CAS:Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.Formula:C9H17NO2·HClPurity:99.46%Color and Shape:Off-White SolidMolecular weight:207.7TTA-A2
CAS:TTA-A2: T-type calcium channel blocker; anticonvulsant targeting Cav3.1, Cav3.2; IC50 of 89/92 nM; potential for treating neurological conditions.Formula:C20H21F3N2O2Purity:98.95% - 99.9%Color and Shape:SolidMolecular weight:378.39Ref: TM-T8944
1mg104.00€5mg255.00€10mg406.00€25mg745.00€50mg1,064.00€100mg1,406.00€1mL*10mM (DMSO)280.00€Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Formula:C26H33NO6Purity:99.98%Color and Shape:White-To-Off-White Crystalline SolidMolecular weight:455.54Nisoldipine
CAS:Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.Formula:C20H24N2O6Purity:98.79% - 99.08%Color and Shape:SolidMolecular weight:388.41Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purity:100% - 99.15%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Dantrolene sodium
CAS:Dantrolene sodium treats spasticity by disrupting muscle contraction; not central in action, grouped with central relaxants.Formula:C14H9N4NaO5Purity:100% - 99.11%Color and Shape:CoaMolecular weight:336.23GSK1016790A
CAS:GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelialFormula:C28H32Cl2N4O6S2Purity:96.25% - 99.05%Color and Shape:SolidMolecular weight:655.61Ref: TM-T6848
1mg37.00€2mg48.00€5mg72.00€10mg113.00€25mg240.00€50mg364.00€100mg540.00€1mL*10mM (DMSO)97.00€14-Deoxyandrographolide
CAS:14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy.Formula:C20H30O4Purity:99.89%Color and Shape:SolidMolecular weight:334.45Urolithin C
CAS:Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.Formula:C13H8O5Purity:97.52% - 98.16%Color and Shape:SolidMolecular weight:244.2Ref: TM-TN7108
5mg52.00€10mg88.00€25mg143.00€50mg235.00€100mg354.00€200mg522.00€500mg825.00€1mL*10mM (DMSO)59.00€Dehydronitrosonisoldipine
CAS:Dehydronitrosonisoldipine blocks SARM1, slows axon decay & cADPR synthesis; useful in neurodegeneration research.Formula:C20H22N2O5Purity:98.02%Color and Shape:SolidMolecular weight:370.4Ref: TM-T10991
1mg52.00€2mg80.00€5mg131.00€10mg177.00€25mg305.00€50mg437.00€100mg562.00€500mg1,121.00€1mL*10mM (DMSO)129.00€Felodipine-13C4, d3
CAS:Controlled ProductApplications Felodipine-13C4, d3 is the labeled analogue of Felodipine (F232375), a dihydropyridine calcium channel blocker. References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981); Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002); O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005); Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006)Formula:C1413C4H16D3Cl2NO4Color and Shape:NeatMolecular weight:391.24Pinocembrin chalcone
CAS:Pinocembrin chalcone: tyrosinase inhibitor, antimutagenic, aids in gastric ulcer prevention studies.Formula:C15H12O4Purity:97.82%Color and Shape:SolidMolecular weight:256.25MDK-4025
CAS:MDK-4025 is an inhibitor of the high voltage-activated (HVA) Ca2+ current in pyramidal neurons.Formula:C19H15ClOPurity:96.73%Color and Shape:SolidMolecular weight:294.771-Benzyl-4-cyano-4-phenylpiperidine Hydrochloride
CAS:Controlled ProductApplications A piperidine derivative as calcium channel blockers. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References McMahon, R. E. , et al.: J. Med. Chem., 22, 1100 (1979),Formula:C19H20N2·ClHColor and Shape:NeatMolecular weight:312.84
