Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Products of "Carbonic Anhydrase"
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Compound CDy9
CAS:Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Formula:C15H16N2O5SPurity:99.75%Color and Shape:SoildMolecular weight:336.36Ref: TM-T67774
2mg38.00€5mg58.00€10mg96.00€25mg170.00€50mg253.00€100mg364.00€200mg512.00€1mL*10mM (DMSO)71.00€Benzolamide
CAS:Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Formula:C8H8N4O4S3Purity:97.03%Color and Shape:SolidMolecular weight:320.37Ref: TM-T23782
5mg51.00€10mg88.00€25mg160.00€50mg235.00€100mg349.00€200mg515.00€1mL*10mM (DMSO)57.00€α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formula:C25H22N6OS2Color and Shape:SolidMolecular weight:486.614-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Formula:C7H8F3N3O4S2Purity:98.58%Color and Shape:SolidMolecular weight:319.28Sultiame
CAS:Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Formula:C10H14N2O4S2Purity:99.86%Color and Shape:SolidMolecular weight:290.36Cyclamic acid sodium
CAS:Sodium cyclamate is a carbonic anhydrase inhibitor, artificial sweetener, with anticonvulsant properties, and used in cancer research.Formula:C6H12NNaO3SPurity:99.84%Color and Shape:SolidMolecular weight:201.22hCAI/II-IN-6
CAS:hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Formula:C19H24N4O3SPurity:97.07%Color and Shape:SolidMolecular weight:388.48hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormula:C18H14FN7O2SPurity:98%Color and Shape:SolidMolecular weight:411.41hCAIX/XII-IN-8
CAS:hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formula:C16H13Cl2N5O3SPurity:98%Color and Shape:SolidMolecular weight:426.28Benzthiazide
CAS:Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.Formula:C15H14ClN3O4S3Purity:100% - 99.79%Color and Shape:Crystals From Acetone SolidMolecular weight:431.94hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFormula:C17H14N6O3SPurity:98%Color and Shape:SolidMolecular weight:382.4CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formula:C19H16ClN3O5S2Molecular weight:465.93Histone acetyltransferase p300 Inhibitor 4c
CAS:2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.Formula:C9H7ClN2SPurity:99.86%Color and Shape:SolidMolecular weight:210.68pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formula:C6H6NO6PPurity:99.73%Color and Shape:SolidMolecular weight:219.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Color and Shape:Lyophilized PowderMolecular weight:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurity:99.42% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:157.19Acetazolamide
CAS:Acetazolamide (Diamox) is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of acetazolamide is Sulfonamides.Formula:C4H6N4O3S2Purity:99.61% - 99.94%Color and Shape:Crystals From Water 1992)Molecular weight:222.245hCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFormula:C11H9N5O3S2Purity:98%Color and Shape:SolidMolecular weight:323.35CA inhibitor 2
Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].Formula:C7H9N7O3S3Purity:98%Color and Shape:SolidMolecular weight:335.39Carbonic anhydrase inhibitor 6
CAS:Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Formula:C26H25N3O5SPurity:98.81%Color and Shape:SolidMolecular weight:491.56
