PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Products of "PPAR"
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EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formula:C21H27ClO5Purity:99% - 99.28%Color and Shape:SolidMolecular weight:394.89Ref: TM-T6829
2mg35.00€5mg50.00€10mg77.00€25mg127.00€50mg202.00€100mg303.00€200mg449.00€1mL*10mM (DMSO)51.00€LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Formula:C21H24ClNO4SPurity:97.15%Color and Shape:SolidMolecular weight:421.94Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Formula:C31H20O10Purity:97.74% - 99.73%Color and Shape:SolidMolecular weight:552.48Ref: TM-T4S2128
1mg47.00€2mg70.00€5mg144.00€10mg250.00€25mg424.00€50mg613.00€100mg843.00€1mL*10mM (DMSO)187.00€Ginsenoside Rh1
CAS:Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.Formula:C36H62O9Purity:99% - 99.77%Color and Shape:SolidMolecular weight:638.87(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Formula:C22H24O4SPurity:98.36%Color and Shape:SolidMolecular weight:384.49Amezalpat
CAS:Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.Formula:C34H41N3O4Color and Shape:SolidMolecular weight:555.70713-Oxo-9E,11E-octadecadienoic acid
CAS:13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.Formula:C18H30O3Purity:98%Color and Shape:SolidMolecular weight:294.43Methyl oleanonate
CAS:3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.Formula:C31H48O3Purity:98.99%Color and Shape:SolidMolecular weight:468.71Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Formula:C20H18F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:437.44Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Formula:C24H20N2O4S2Purity:98%Color and Shape:SolidMolecular weight:464.56Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFormula:C30H30N2O7Purity:97.75%Color and Shape:SolidMolecular weight:530.57Gypenoside XLIX
CAS:Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry conditionFormula:C52H86O21Purity:99.59% - 99.78%Color and Shape:SolidMolecular weight:1047.23KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Formula:C30H33F3N2O8S2Purity:99.61%Color and Shape:SolidMolecular weight:670.72EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Formula:C28H35NO3Purity:99.22%Color and Shape:SolidMolecular weight:433.58Ref: TM-T13289
1mg107.00€5mg227.00€10mg378.00€25mg620.00€50mg868.00€100mg1,169.00€1mL*10mM (DMSO)250.00€PPARγ-IN-3
PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.Formula:C23H28FN7O3Color and Shape:SolidMolecular weight:469.51GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Formula:C26H34F2N2O3SPurity:98%Color and Shape:SolidMolecular weight:492.62PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Formula:C26H21NO7S3SeColor and Shape:SolidMolecular weight:634.6Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Formula:C13H14Cl2O3Purity:100% - 99.95%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist, with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.Formula:C13H9ClN2O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:276.68Pioglitazone
CAS:Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes.Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44Oleuropein
CAS:Oleuropein is an antioxidant polyphenol isolated from olive leaf.Formula:C25H32O13Purity:98% - 99.95%Color and Shape:Brown PowderMolecular weight:540.51PPARγ agonist 15
PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.Formula:C21H16N4O3S2Color and Shape:SolidMolecular weight:436.51MCC-555
CAS:MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.Formula:C21H16FNO3SPurity:98.56% - 99.07%Color and Shape:SolidMolecular weight:381.42Ref: TM-T21764
5mg70.00€10mg111.00€25mg226.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)77.00€Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Formula:C25H25NO5Purity:98.95% - 99.33%Color and Shape:SolidMolecular weight:419.47PPARγ-IN-5
CAS:PPARγ-IN-5 (Compound A3) is an inhibitor of PPARγ. In liver cells, it reduces lipid accumulation and shows no significant cytotoxicity in HepG2 cells at a concentration of 400 µM. PPARγ-IN-5 is applicable for research on non-alcoholic fatty liver disease.Formula:C22H23ClO7Color and Shape:SolidMolecular weight:434.867Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84E0924G
CAS:E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.Formula:C12H12N2O3Color and Shape:SolidMolecular weight:232.24(±)4-HDHA
CAS:(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.Formula:C22H32O3Purity:99.05%Color and Shape:SolidMolecular weight:344.49Ref: TM-T36602
1mg1,539.00€5mg3,087.00€10mg4,170.00€25mg6,194.00€25μg (2.90mM*25μL in MeOH)160.00€50μg (2.90mM*50μL in MeOH)283.00€100μg (2.90mM*100μL in MeOH)538.00€GSK3787
CAS:GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6).Formula:C15H12ClF3N2O3SPurity:98% - 98.53%Color and Shape:SolidMolecular weight:392.78Ref: TM-T1941
5mg55.00€10mg87.00€25mg173.00€50mg309.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)55.00€Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Formula:C14H14ClN3O2SPurity:98.27% - 99.92%Color and Shape:SolidMolecular weight:323.8Ref: TM-T2269
1g350.00€10mg48.00€25mg64.00€50mg79.00€100mg105.00€200mg148.00€500mg236.00€1mL*10mM (DMSO)47.00€Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Formula:C27H26N4O4SPurity:98.00% - 99.58%Color and Shape:SolidMolecular weight:502.58Ref: TM-T15581
1mg73.00€5mg158.00€10mg244.00€25mg394.00€50mg562.00€100mg753.00€500mgTo inquire1mL*10mM (DMSO)188.00€Furegrelate
CAS:FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.Formula:C15H11NO3Purity:100%Color and Shape:SolidMolecular weight:253.25Ref: TM-T11339L
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)226.00€Linotroban
CAS:Linotroban(CL-871502) is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Formula:C14H15NO5S2Purity:100% - 99.31%Color and Shape:SolidMolecular weight:341.4GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.5PPARα/δ agonist 3
CAS:PPARα/δ agonist 3 (Compound 8) is an orally active PPAR agonist capable of activating PPARα, PPARδ, and PPARγ, with EC50 values of 5.6 nM, 3.4 nM, and 1278 nM, respectively. It exhibits anti-cholestatic activity in mouse models of cholestatic liver disease induced by ANIT or CDCA.Formula:C23H25F3N2O4Color and Shape:SolidMolecular weight:450.451LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Formula:C27H22O3Purity:99.64%Color and Shape:SolidMolecular weight:394.46Ref: TM-T8374
1mg145.00€2mg213.00€5mg329.00€10mg470.00€25mg718.00€50mg938.00€100mg1,301.00€500mg2,612.00€1mL*10mM (DMSO)354.00€NPC 15199
CAS:NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.Formula:C21H23NO4Purity:99.94%Color and Shape:White Crystalline PowderMolecular weight:353.41Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.75Daidzein
CAS:Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.Formula:C15H10O4Purity:98.08%Color and Shape:SolidMolecular weight:254.24Foenumoside B
CAS:Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotesFormula:C60H96O25Purity:98%Color and Shape:SolidMolecular weight:1217.39CUDA
CAS:CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.Formula:C19H36N2O3Purity:≥98%Color and Shape:SolidMolecular weight:340.5MSDC-0602K
CAS:MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.Formula:C19H16KNO5SPurity:99.89%Color and Shape:SolidMolecular weight:409.5WAY-620472
CAS:WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.Formula:C23H21N5OSPurity:98.07%Color and Shape:SolidMolecular weight:415.51AZD-9574
CAS:AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.Formula:C21H22F2N6O2Purity:98.39% - 98.55%Color and Shape:SolidMolecular weight:428.44MK-0533
CAS:MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.Formula:C28H24F3NO6Purity:99.64%Color and Shape:SoildMolecular weight:527.49Alpinetin
CAS:Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.Formula:C16H14O4Purity:98.39%Color and Shape:SolidMolecular weight:270.28Cloxiquine
CAS:Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.Formula:C9H6ClNOPurity:99.87%Color and Shape:Light Yellow CrystalsMolecular weight:179.6LY518674
CAS:LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.Formula:C23H27N3O4Purity:98.87%Color and Shape:SolidMolecular weight:409.48Ref: TM-T15821
1mg170.00€5mg359.00€10mg533.00€25mg847.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)398.00€Anti-osteoporosis agent-10
Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.Color and Shape:Odour SolidDarglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Formula:C23H20N2O4SPurity:99.19%Color and Shape:SolidMolecular weight:420.48Farglitazar
CAS:Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.Formula:C34H30N2O5Purity:99.40% - 99.65%Color and Shape:SolidMolecular weight:546.61Rosiglitazone sodium
CAS:Rosiglitazone sodium is an effective and selective PPARγ activator, with EC50 values of 30 nM for PPARγ1, 100 nM for PPARγ2, and 60 nM for PPARγ. It also has an approximate Kd of 40 nM for PPARγ. Additionally, Rosiglitazone sodium acts as a regulator of TRP channels, inhibiting the activities of TRPM2 and TRPM3, while activating TRPC5.Formula:C18H18N3NaO3SColor and Shape:SolidMolecular weight:379.41PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:31.49 kDa (predicted)Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Formula:C25H29NO4SPurity:98.49%Color and Shape:SolidMolecular weight:439.57Glabrone
CAS:Glabrone shows antiviral activity against influenza virus.Formula:C20H16O5Purity:99.08% - 99.55%Color and Shape:SolidMolecular weight:336.34Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.36%Color and Shape:SolidMolecular weight:254.41SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.60%Color and Shape:SolidMolecular weight:357.75CRX000227
CAS:CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55Sulotroban potassium
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.Formula:C16H16KNO5SPurity:98.04%Color and Shape:SoildMolecular weight:373.46THR-0921
CAS:THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.Formula:C28H25NO7SPurity:98.53%Color and Shape:SolidMolecular weight:519.57Furegrelate sodium
CAS:Furegrelate sodium (U-63557A) is an orally active thromboxane synthase inhibitor with an IC50 of 15 nM in platelets.Formula:C15H10NNaO3Purity:100%Color and Shape:SolidMolecular weight:275.23Ref: TM-T11339
5mg35.00€10mg52.00€25mg109.00€50mg202.00€100mg324.00€500mgTo inquire1mL*10mM (DMSO)37.00€K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Formula:C18H25Cl3O2Purity:99.88% - 99.93%Color and Shape:SolidMolecular weight:379.75
