PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Products of "PPAR"
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CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Formula:C26H33NO5Purity:99.84%Color and Shape:SolidMolecular weight:439.54BAY-0069
CAS:BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can beFormula:C22H16BrN3O4Purity:99.41%Color and Shape:SoildMolecular weight:466.28Bezafibrate
CAS:Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES.Formula:C19H20ClNO4Purity:99.56% - 99.82%Color and Shape:SolidMolecular weight:361.82MA-0204
CAS:MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,Formula:C25H27F3N2O4Purity:97.80%Color and Shape:SolidMolecular weight:476.49Ref: TM-T15945
1mg96.00€5mg178.00€10mg301.00€25mg490.00€50mg677.00€100mg900.00€200mg1,206.00€1mL*10mM (DMSO)187.00€DG172 dihydrochloride
CAS:DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).Formula:C20H22BrCl2N3Purity:99.87%Color and Shape:SolidMolecular weight:455.2Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Formula:C13H8O6Purity:98.90% - 98.93%Color and Shape:SolidMolecular weight:260.2Ref: TM-TN1990
1mg149.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)522.00€T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.Formula:C12H8ClN3O3Purity:99.36% - 99.95%Color and Shape:SolidMolecular weight:277.66Ref: TM-T6689
5mg49.00€10mg58.00€25mg92.00€50mg147.00€100mg197.00€200mg255.00€500mg430.00€1mL*10mM (DMSO)55.00€MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurity:98.9% - 99.78%Color and Shape:SolidMolecular weight:472.08Ref: TM-T6893
1mg35.00€2mg48.00€5mg70.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)72.00€Mavodelpar free acid hydrochloride
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.Formula:C31H31ClFNO5Purity:99.39%Color and Shape:SoildMolecular weight:552.03Arhalofenate
CAS:Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.Formula:C19H17ClF3NO4Purity:98.97%Color and Shape:SolidMolecular weight:415.79Ref: TM-T16022
1mg131.00€5mg286.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€500mg2,688.00€1mL*10mM (DMSO)330.00€Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Formula:C16H17NO5SPurity:98.35% - 99.29%Color and Shape:SolidMolecular weight:335.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purity:98%Color and Shape:SolidMolecular weight:440.45Clofibrate
CAS:Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.Formula:C12H15ClO3Purity:98.77%Color and Shape:Oil LiquidMolecular weight:242.7ARH-049020
CAS:ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.Formula:C24H31NO6Purity:99.67% - 99.82%Color and Shape:SolidMolecular weight:429.51FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Formula:C16H7ClF2N2OPurity:98.68%Color and Shape:SolidMolecular weight:316.69Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg58.00€5mg97.00€10mg160.00€25mg283.00€50mg418.00€100mg615.00€200mg878.00€1mL*10mM (DMSO)111.00€GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Formula:C32H37NO6Purity:100%Color and Shape:SolidMolecular weight:531.64NSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Formula:C19H13N3O7S2Purity:97.35%Color and Shape:SolidMolecular weight:459.45PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:31.36 kDa (predicted)Ankaflavin
CAS:Ankaflavin, from red rice fermentation, is a PPARγ agonist with anti-inflammatory properties and selectively kills cancer cells.Formula:C23H30O5Purity:98%Color and Shape:SolidMolecular weight:386.48Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Formula:C20H17N3O4SPurity:99.74%Color and Shape:SolidMolecular weight:395.43GW0742
CAS:GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Formula:C21H17F4NO3S2Purity:99.75% - 99.85%Color and Shape:SolidMolecular weight:471.49GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).Formula:C30H29N3O4Purity:98.1% - 98.21%Color and Shape:SolidMolecular weight:495.57PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Formula:C20H25NO6SPurity:98%Color and Shape:SolidMolecular weight:407.48Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.Formula:C16H32O2SPurity:≥98%Color and Shape:SolidMolecular weight:288.49Ref: TM-T9808
5mg47.00€10mg70.00€25mg111.00€50mg170.00€100mg264.00€200mg398.00€500mg647.00€1mL*10mM (DMSO)50.00€Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Formula:C28H36O8Purity:97.23% - 99.95%Color and Shape:SolidMolecular weight:500.58Ref: TM-TN1018
1mg55.00€5mg117.00€10mg182.00€25mg306.00€50mg444.00€100mg610.00€1mL*10mM (DMSO)158.00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Formula:C25H27F3N2O3Purity:98.05%Color and Shape:SolidMolecular weight:460.49Ref: TM-T39516
1mg120.00€5mg274.00€10mg411.00€25mg742.00€50mg1,111.00€100mg1,549.00€1mL*10mM (DMSO)279.00€Anti-NASH agent 1
CAS:Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).Formula:C26H33NO4Purity:98%Color and Shape:SolidMolecular weight:423.54GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Formula:C19H18N2O5S2Purity:100% - ≥95%Color and Shape:SolidMolecular weight:418.49Ref: TM-T2674
2mg47.00€5mg69.00€10mg104.00€25mg185.00€50mg369.00€100mg548.00€500mg1,198.00€1mL*10mM (DMSO)69.00€Fenofibrate
CAS:Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.Formula:C20H21ClO4Purity:99.13% - 99.95%Color and Shape:Crystals From Isopropanol SolidMolecular weight:360.83SP4e
SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.Formula:C22H17ClN2O2S2Purity:99.79%Color and Shape:SoildMolecular weight:440.97Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Formula:C19H16BrNO3SPurity:99.12%Color and Shape:SolidMolecular weight:418.3Lonazolac
CAS:Lonazolac is a nonsteroidal anti-inflammatory drug[1].Formula:C17H13ClN2O2Purity:99.40%Color and Shape:SolidMolecular weight:312.75Ref: TM-T50025
5mg57.00€10mg86.00€25mg131.00€50mg188.00€100mg284.00€200mg426.00€1mL*10mM (DMSO)74.00€Cevoglitazar
CAS:Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.Formula:C27H21F3N2O6SPurity:97.39%Color and Shape:SolidMolecular weight:558.53Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂,可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性,IC50为140 μM,具有抗肥胖和抗糖尿病作用。Formula:C11H17ClO7P2Purity:99.12%Color and Shape:SolidMolecular weight:358.65Ref: TM-T16074
1mg52.00€5mg111.00€10mg180.00€25mg303.00€50mg449.00€100mg645.00€1mL*10mM (DMSO)124.00€Cinnamyl alcohol
CAS:Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Formula:C9H10OPurity:99.00%Color and Shape:Colourless LiquidMolecular weight:134.18Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Formula:C25H23F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:504.52GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Formula:C35H36F3N3O4Purity:98.23% - 99.55%Color and Shape:SolidMolecular weight:619.67Ref: TM-T8486
1mg38.00€5mg80.00€10mg105.00€25mg215.00€50mg426.00€100mg623.00€500mg1,293.00€1mL*10mM (DMSO)120.00€BADGE
CAS:Bisphenol a diglycidyl ether is a Standardized Chemical Allergen.Formula:C21H24O4Purity:85.3%Color and Shape:Sticky Bisphenol A Diglycidyl Ether Is An Odorless Yellowish Brown Liquid Sinks In Water (Uscg 1999)Molecular weight:340.41Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFormula:C19H20N2O3S·HClPurity:100% - 99.66%Color and Shape:White Crystals Or Crystalline PowderMolecular weight:392.9PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFormula:C26H28ClF3N4O3SPurity:98%Color and Shape:SolidMolecular weight:569.04Elafibranor
CAS:Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) withFormula:C22H24O4SPurity:99.5% - 99.55%Color and Shape:SolidMolecular weight:384.49Ref: TM-T4408
2mg35.00€5mg52.00€10mg80.00€25mg135.00€50mg215.00€100mg354.00€500mg825.00€1mL*10mM (DMSO)57.00€Gemfibrozil
CAS:Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.Formula:C15H22O3Purity:99.53% - 99.88%Color and Shape:Crystals From Hexane SolidMolecular weight:250.33Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.49%Color and Shape:SolidMolecular weight:676.66BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Formula:C22H16ClN3O4Purity:99.47%Color and Shape:SoildMolecular weight:421.83Ref: TM-T67933
1mg40.00€5mg88.00€10mg126.00€25mg274.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)97.00€Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Formula:C27H28Cl2N4O4SColor and Shape:SolidMolecular weight:575.51Licarin B
CAS:1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.Formula:C20H20O4Purity:100% - ≥95%Color and Shape:SolidMolecular weight:324.37SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formula:C16H11ClF3N3O2SPurity:99.74%Color and Shape:SolidMolecular weight:401.79
