PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Products of "PPAR"
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Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFormula:C22H37NO2Purity:98.76% - 99.22%Color and Shape:Light Yellow OilMolecular weight:347.53Ref: TM-T14046
1mg35.00€2mg49.00€5mg74.00€10mg131.00€25mg246.00€50mg366.00€100mg538.00€200mg752.00€1mL*10mM (DMSO)81.00€Reglitazar
CAS:Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.Formula:C22H20N2O5Purity:97.07% - 98.72%Color and Shape:SolidMolecular weight:392.4Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Oroxin A
CAS:Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.Formula:C21H20O10Purity:98.05% - 99.74%Color and Shape:SolidMolecular weight:432.38Ref: TM-T5S0788
1mg43.00€5mg87.00€10mg135.00€25mg224.00€50mg369.00€100mg509.00€500mg1,093.00€1mL*10mM (DMSO)95.00€(±)-CBCQ
CAS:(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).Formula:C21H28O3Color and Shape:SolidMolecular weight:328.455-Aminosalicylic Acid
CAS:5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.Formula:C7H7NO3Purity:98.88% - 99.98%Color and Shape:Purplish-Tan Solid PowderMolecular weight:153.14Fenofibric acid
CAS:Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.Formula:C17H15ClO4Purity:99.36%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:318.75Aleglitazar
CAS:Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.Formula:C24H23NO5SPurity:99.42%Color and Shape:SolidMolecular weight:437.51Ref: TM-T14176
1mg245.00€5mg562.00€10mg758.00€25mg1,159.00€50mg1,568.00€100mg2,110.00€1mL*10mM (DMSO)568.00€PPARγ-IN-2
CAS:"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.Formula:C19H21N5OPurity:98%Color and Shape:SolidMolecular weight:335.4Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFormula:C20H24O7SPurity:99.89%Color and Shape:SolidMolecular weight:408.47Ref: TM-T17044
1mg46.00€5mg87.00€10mg137.00€25mg255.00€50mg472.00€100mg687.00€500mg1,444.00€1mL*10mM (DMSO)106.00€Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Formula:C15H10O6Purity:94.14% - 98.31%Color and Shape:Yellow To Brown Crystalline PowderMolecular weight:286.24PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Formula:C19H14BrNO4SColor and Shape:SolidMolecular weight:432.29β-Amyrone
CAS:beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.Formula:C30H48OPurity:99.55%Color and Shape:SolidMolecular weight:424.7Chiglitazar
CAS:Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.Formula:C36H29FN2O4Color and Shape:SolidMolecular weight:572.63Dazmegrel
CAS:Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.Formula:C16H17N3O2Purity:99.20%Color and Shape:SolidMolecular weight:283.33Suksdorfin
CAS:Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .Formula:C21H24O7Purity:98.43%Color and Shape:SolidMolecular weight:388.41Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.Formula:C24H23NO5SPurity:99.18%Color and Shape:SoildMolecular weight:437.51Ref: TM-T63898
1mg185.00€5mg426.00€10mg627.00€25mg938.00€50mg1,320.00€100mg1,786.00€1mL*10mM (DMSO)472.00€Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurity:98% - 99.62%Color and Shape:Yellow SolidMolecular weight:441.54Ref: TM-T3170
2mg42.00€5mg62.00€10mg88.00€25mg172.00€50mg305.00€100mg558.00€500mg1,169.00€1mL*10mM (DMSO)85.00€Convallatoxin
CAS:Convallatoxin is a natural product.Formula:C29H42O10Purity:99.27%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64Oleoylethanolamide
CAS:Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.Formula:C20H39NO2Purity:99.98%Color and Shape:SolidMolecular weight:325.53Ref: TM-T12296
2mg35.00€5mg52.00€10mg80.00€25mg145.00€50mg250.00€100mg376.00€200mg550.00€1mL*10mM (DMSO)58.00€Glabridin
CAS:Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Formula:C20H20O4Purity:99.78% - 99.99%Color and Shape:Light Yellow Powder Insoluble In WaterMolecular weight:324.37CGS 15435
CAS:CGS 15435: potent TxA2 synthase inhibitor, IC50=1 nM; less selective for PGI2 synthase, COX, and liposynthase.Formula:C20H21ClN2O2Purity:99.63%Color and Shape:SolidMolecular weight:356.85Seladelpar
CAS:Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.Formula:C21H23F3O5SPurity:99.07% - 99.20%Color and Shape:SolidMolecular weight:444.46Mavodelpar free base
CAS:Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.Formula:C31H30FNO5Purity:98%Color and Shape:SolidMolecular weight:515.57GW590735
CAS:GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.Formula:C23H21F3N2O4SPurity:99.12%Color and Shape:SolidMolecular weight:478.48Ref: TM-T9766
1mg95.00€5mg202.00€10mg298.00€25mg507.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)213.00€GW7647
CAS:GW 7647 is an effective and highly selective PPARα agonist. GW 7647 can reduce the production of nitric oxide in macrophages. Cost-effective and quality-assured.Formula:C29H46N2O3SPurity:99.30% - 99.34%Color and Shape:SolidMolecular weight:502.75Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurity:99.33% - 99.51%Color and Shape:Off-White SolidMolecular weight:473.5FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Ref: TM-T2413
5mg38.00€10mg57.00€25mg94.00€50mg164.00€100mg274.00€200mg404.00€500mg653.00€1mL*10mM (DMSO)64.00€Raspberry ketone
CAS:1.Formula:C10H12O2Purity:99.84% - 99.89%Color and Shape:White Solid CrystallineMolecular weight:164.2PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Formula:C27H37NO5Purity:98%Color and Shape:SolidMolecular weight:455.59LG100754
CAS:LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.Formula:C26H36O3Color and Shape:SolidMolecular weight:396.56AMG131
CAS:AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used forFormula:C21H12Cl4N2O3SPurity:99.37%Color and Shape:SolidMolecular weight:514.21SR1664
CAS:SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.Formula:C33H29N3O5Purity:98.02%Color and Shape:SolidMolecular weight:547.6Ref: TM-T23389
1mg52.00€2mg74.00€5mg111.00€10mg144.00€25mg305.00€50mg543.00€100mg780.00€500mg1,605.00€1mL*10mM (DMSO)123.00€NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42CC618
CAS:CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.Formula:C20H15F6N3O3S2Purity:99.37%Color and Shape:SolidMolecular weight:523.47Ref: TM-T9767
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)314.00€PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFormula:C19H12F4O2SPurity:98%Color and Shape:SolidMolecular weight:380.36Clofibric acid
CAS:Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.Formula:C10H11ClO3Purity:99.47% - 99.8%Color and Shape:Pale Yellow SolidMolecular weight:214.65OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purity:100% - 98.3%Color and Shape:SolidMolecular weight:541.72Ref: TM-TQ0120
1mg37.00€5mg79.00€10mg111.00€25mg210.00€50mg338.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)94.00€Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Daltroban
CAS:Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.Formula:C16H16ClNO4SPurity:99.49%Color and Shape:SolidMolecular weight:353.82Ref: TM-T15049
1mg58.00€5mg129.00€10mg187.00€25mg311.00€50mg444.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)117.00€AVE-8134
CAS:AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.Formula:C22H23NO5Purity:98%Color and Shape:SolidMolecular weight:381.42PPARδ agonist 11
CAS:Compound 11, a selective PPARδ agonist, demonstrates an EC50 of 20 nM, indicating its high affinity for PPARδ receptors. This compound efficiently reduces levels of nitric oxide (NO), as well as the pro-inflammatory cytokines TNFα and IL-6 in LPS-stimulated RAW264.7 cells via the NF-κB pathway, showcasing its anti-inflammatory properties. Additionally, Compound 11 exhibits remarkable stability in human liver microsomes and plasma. It significantly ameliorates foot edema induced by Carrageenan, displaying favorable pharmacokinetic properties with a bioavailability of approximately 100%.Formula:C19H15F3N2O3S2Color and Shape:SolidMolecular weight:440.46Muraglitazar
CAS:Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.Formula:C29H28N2O7Purity:99.31%Color and Shape:SolidMolecular weight:516.54SP4f
SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells.Purity:98%Color and Shape:Odour SolidOroxin A
CAS:Oroxin A, a partial PPARγ agonist, activates PPARγ, inhibits α-glucosidase, and has antioxidant properties.Formula:C21H20O10Purity:98%Color and Shape:SolidMolecular weight:432.38Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.42% - 99%Color and Shape:SolidMolecular weight:344.32Indeglitazar
CAS:Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).Formula:C19H19NO6SPurity:99.73%Color and Shape:SolidMolecular weight:389.42Magnolol
CAS:Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formula:C18H18O2Purity:99.49%Color and Shape:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaMolecular weight:266.33L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Formula:C22H26O7Purity:97.97%Color and Shape:SolidMolecular weight:402.44
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