Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
Products of "Phospholipase"
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GW4869
CAS:GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM).Formula:C30H30Cl2N6O2Purity:98.47% - 99.66%Color and Shape:SolidMolecular weight:577.51-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Formula:C40H76NO8PColor and Shape:SolidMolecular weight:730.01VU0155069
CAS:VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.Formula:C26H27ClN4O2Purity:98.32%Color and Shape:SolidMolecular weight:462.97N-(p-amylcinnamoyl) Anthranilic Acid
CAS:N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.Formula:C21H23NO3Purity:99.35% - 99.67%Color and Shape:SolidMolecular weight:337.41Lp-PLA2-IN-3
CAS:Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.Formula:C20H13ClF3N3O3SPurity:99.49%Color and Shape:SolidMolecular weight:467.85Ref: TM-T11874
1mg96.00€2mg139.00€5mg227.00€10mg359.00€25mg595.00€50mg842.00€100mg1,121.00€500mg2,262.00€1mL*10mM (DMSO)233.00€nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Formula:C12H17N5OPurity:98%Color and Shape:SolidMolecular weight:247.3U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64ML-298
CAS:ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).Formula:C22H23F3N4O2Purity:99.35%Color and Shape:SolidMolecular weight:432.44FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purity:98.01% - 99.08%Color and Shape:SolidMolecular weight:421.47Atg4B-IN-2
CAS:Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.Formula:C21H30O3Purity:98.86%Color and Shape:SolidMolecular weight:330.46Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.57%Color and Shape:Clear In WaterMolecular weight:367.4Lp-PLA2-IN-15
CAS:Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].Formula:C22H17F5N4O3Purity:98%Color and Shape:SolidMolecular weight:480.39Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Formula:C21H17F5N4O3Purity:99.25%Color and Shape:SolidMolecular weight:468.38Neomycin sulfate
CAS:Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exertFormula:C23H46N6O13·3H2SO4Purity:98.79% - 99.87%Color and Shape:Tan PowderMolecular weight:908.87Lp-PLA2-IN-13
CAS:Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].Formula:C22H17F5N4O4Purity:98%Color and Shape:SolidMolecular weight:496.39DPTIP hydrochloride
CAS:DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.Formula:C21H19ClN2O3SColor and Shape:SolidMolecular weight:414.91Halopemide
CAS:Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).Formula:C21H22ClFN4O2Purity:96.29%Color and Shape:SolidMolecular weight:416.88Niflumic acid
CAS:Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.Formula:C13H9F3N2O2Purity:99.47%Color and Shape:SolidMolecular weight:282.22BIRM 271
CAS:BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.Formula:C21H25N3OPurity:99.38%Color and Shape:SoildMolecular weight:335.44VU0155056
CAS:VU0155056 is a dual PLD1/2 inhibitor with IC50 < 1 µM in cellular assays, inhibits breast cancer cell invasion.Formula:C25H26N4O2Purity:98.6%Color and Shape:SolidMolecular weight:414.5
