5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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Azasetron hydrochloride
CAS:Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.Formula:C17H20ClN3O3·HClPurity:99.50%Color and Shape:SolidMolecular weight:386.27Trimipramine maleate
CAS:Trimipramine maleate, a tricyclic antidepressant, blocks serotonin and norepinephrine reuptake, boosting their levels and duration.Formula:C24H30N2O4Purity:99.47%Color and Shape:SolidMolecular weight:410.51Ritanserin
CAS:Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.Formula:C27H25F2N3OSPurity:99.45% - 99.89%Color and Shape:SolidMolecular weight:477.57Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formula:C11H12F3NOPurity:98%Color and Shape:SolidMolecular weight:231.21DREADD agonist 21
CAS:DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).Formula:C17H18N4Purity:99.88%Color and Shape:SolidMolecular weight:278.35Ref: TM-T11095L
2mg34.00€5mg58.00€10mg85.00€25mg140.00€50mg221.00€100mg329.00€200mg472.00€1mL*10mM (DMSO)52.00€Mosapride Citrate
CAS:Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.Formula:C21H25ClFN3O3·C6H8O7Purity:99.70%Color and Shape:White PowderMolecular weight:614.02Itasetron
CAS:Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.Formula:C16H20N4O2Purity:100% - 99.63%Color and Shape:SolidMolecular weight:300.364-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Formula:C9H10ClNO2Purity:99.76% - 99.96%Color and Shape:SolidMolecular weight:199.63Isocorynoxeine
CAS:Isocorynoxeine reduces blood pressure, dilates vessels, and guards neurons against ischemia and glutamate toxicity.Formula:C22H26N2O4Purity:98% - 99.9%Color and Shape:SolidMolecular weight:382.45Donitriptan
CAS:Donitriptan 是一种 5-HT 受体激动剂,对 5-HT1B 和 5-HT1D 的 pKi 分别为 9.4 和 9.3。Formula:C23H25N5O2Purity:98.34%Color and Shape:SolidMolecular weight:403.485-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColor and Shape:SolidMolecular weight:244.33PRX-07034 hydrochloride
CAS:PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and decreases body weight in rodents.Formula:C21H29Cl2N3O4SPurity:98.50%Color and Shape:SolidMolecular weight:490.44Naftidrofuryl oxalate
CAS:Naftidrofuryl oxalate treats peripheral/cerebral vascular issues, boosts cell oxidation, is spasmolytic, and may block 5HT-2 serotonin receptors.Formula:C26H35NO7Purity:97.12% - 98.38%Color and Shape:SolidMolecular weight:473.567-Desmethyl-3-hydroxyagomelatine
CAS:7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.Formula:C14H15NO3Purity:98%Color and Shape:SolidMolecular weight:245.27Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Formula:C19H28ClN5OColor and Shape:SolidMolecular weight:377.91Org-12962
CAS:Org-12962: 5-HT2C agonist (pEC50: 7.01), anti-panic in rats, affects 5-HT2A/B (pEC50: 6.38/6.28).Formula:C10H11ClF3N3Purity:98.34%Color and Shape:SolidMolecular weight:265.66Perphenazine
CAS:Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.Formula:C21H26ClN3OSPurity:99.3% - 99.72%Color and Shape:SolidMolecular weight:403.97Eplivanserin
CAS:Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.Formula:C19H21FN2O2Purity:97.04%Color and Shape:SolidMolecular weight:328.38Zotepine
CAS:Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,Formula:C18H18ClNOSPurity:99.78%Color and Shape:SolidMolecular weight:331.86Jatrorrhizine
CAS:Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species.Formula:C20H20NO4Purity:97.18% - 99.06%Color and Shape:SolidMolecular weight:338.38Pridefine
CAS:Pridefine: antidepressant, balances serotonin, dopamine, norepinephrine reuptake, weakly releases them.Formula:C19H21NPurity:99.05% - 99.23%Color and Shape:SolidMolecular weight:263.38YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.38-OH-Dpat
CAS:8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.Formula:C16H25NOPurity:98%Color and Shape:SolidMolecular weight:247.38Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formula:C15H22N2Color and Shape:SolidMolecular weight:230.35Sarpogrelate hydrochloride
CAS:Sarpogrelate hydrochloride (MCI-9042), a 5-HT2 antagonist with high affinity (Ki=8.39nM), is used as an anti-platelet for PAD, improving vascular function.Formula:C24H32ClNO6Purity:99.73%Color and Shape:Colorless LiquidMolecular weight:465.97Dolasetron Mesylate
CAS:Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea followingFormula:C20H24N2O6SPurity:100%Color and Shape:White PowderMolecular weight:420.48Deramciclane
CAS:Deramciclane has high affinity for 5-HT2A and 5-HT2C receptors.Formula:C20H31NOColor and Shape:SolidMolecular weight:301.47NPS ALX Compound 4a
CAS:NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Formula:C25H25N3O2SPurity:98%Color and Shape:SolidMolecular weight:431.55AAZ-A 154 benzoate
CAS:AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44Nardosinonediol
CAS:Nardosinonediol is a natural compound derived from Nardostachys jatamansi that acts as a SERT inhibitor, regulating serotonin levels and antidepressant.Formula:C15H24O3Purity:98%Color and Shape:SolidMolecular weight:252.35Pimethixene
CAS:Pimethixene (Calmixen) blocks 5-HT1A, 2A/B/C, H1, D2/D4.4 & muscarinic M1/M2 receptors; potent with pKis 7.54-10.44.Formula:C19H19NSPurity:97.50%Color and Shape:SolidMolecular weight:293.43Ref: TM-T12489
2mg34.00€5mg50.00€10mg65.00€25mg106.00€50mg158.00€100mg226.00€200mg339.00€1mL*10mM (DMSO)52.00€SB-269970 hydrochloride
CAS:SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivityFormula:C18H28N2O3S·HClPurity:98.45%Color and Shape:SolidMolecular weight:388.95Ogerin
CAS:Ogerin: GPR68 modulator, blocks mice fear recall, A2A inverse agonist/antagonist (Ki 220 nM), weak 5-HT2B antagonist (Ki 736 nM).Formula:C17H17N5OPurity:99.50% - 99.75%Color and Shape:SolidMolecular weight:307.35Ref: TM-T16378
1mg35.00€2mg52.00€5mg74.00€10mg115.00€25mg227.00€50mg380.00€100mg567.00€1mL*10mM (DMSO)86.00€Tandospirone citrate
CAS:Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)Formula:C27H37N5O9Purity:97.84% - 99.83%Color and Shape:SolidMolecular weight:575.61Quinupramine
CAS:Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.Formula:C21H24N2Purity:99.76%Color and Shape:SolidMolecular weight:304.43PF-03382792
CAS:PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Formula:C23H32FN3O4Purity:98.09%Color and Shape:SolidMolecular weight:433.52NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Formula:C25H26ClN3O2SPurity:99.8%Color and Shape:SoildMolecular weight:468.01Ref: TM-T12262L1
1mg52.00€5mg114.00€10mg172.00€25mg284.00€50mg411.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)138.00€Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Formula:C22H26FN3O4Color and Shape:SolidMolecular weight:415.46Serazapine
CAS:Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.Formula:C22H23N3O2Purity:98.06% - 99%Color and Shape:SolidMolecular weight:361.44VA012
CAS:VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.Formula:C21H19N3Color and Shape:SolidMolecular weight:313.40Dapoxetine hydrochloride
CAS:Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.Formula:C21H23NO·HClPurity:99.5% - 99.70%Color and Shape:White To Off-White Crystalline SolidMolecular weight:341.87Amitriptyline hydrochloride
CAS:Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptiveFormula:C20H24ClNPurity:97% - 99.94%Color and Shape:Crystals White To Off-White PowderMolecular weight:313.865-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Formula:C16H21ClN4O3Purity:98%Color and Shape:SolidMolecular weight:352.82Piclozotan
CAS:Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO)Formula:C23H24ClN3O2Purity:99%Color and Shape:SolidMolecular weight:409.91NPS ALX Compound 4a dihydrochloride
CAS:NPS ALX Compound 4a dihydrochloride is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Formula:C25H27Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:504.47Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Formula:C15H19ClN4OPurity:99.72%Color and Shape:SolidMolecular weight:306.79BIMU 8
CAS:BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formula:C19H27ClN4O2Purity:99.36%Color and Shape:SolidMolecular weight:378.9Ref: TM-T21946
1mg89.00€5mg172.00€10mg249.00€25mg416.00€50mg615.00€100mg873.00€500mg1,768.00€1mL*10mM (DMSO)185.00€Repinotan HCl
CAS:Repinotan HCl (Bay-x-3702) is a 5-HT1A receptor agonist with potent neuroprotective effects for the study of ischemic stroke and traumatic brain injury.Formula:C21H25ClN2O4SPurity:99.57%Color and Shape:SolidMolecular weight:436.95BF-1
CAS:BF-1 blocks 5-HT2B, may prevent migraines by hindering BW723C86/mCPP in guinea pigs.Formula:C22H25NO2SPurity:100% - 99.25%Color and Shape:SolidMolecular weight:367.50Vortioxetine hydrobromide
CAS:Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33Formula:C18H22N2S·HBrPurity:100% - 99.89%Color and Shape:SolidMolecular weight:379.36BRL 54443
CAS:BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).Formula:C14H18N2OPurity:98.07%Color and Shape:SolidMolecular weight:230.31Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurity:99.99%Color and Shape:Crystalline SolidMolecular weight:327.9Ref: TM-T4274
10mg47.00€25mg67.00€50mg87.00€100mg116.00€200mg170.00€500mg279.00€1mL*10mM (DMSO)50.00€NLX-204 hydrochloride(2170405-10-2 free base)
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).Formula:C20H23Cl2F2N3O2Purity:99.59%Color and Shape:SolidMolecular weight:446.32Rotundine
CAS:Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.Formula:C21H25NO4Purity:100% - 99.8%Color and Shape:Off-White SolidMolecular weight:355.43Iloperidone
CAS:Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.Formula:C24H27FN2O4Purity:99.42%Color and Shape:SolidMolecular weight:426.48EMDT
CAS:EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.Formula:C15H22N2OPurity:98.33% - 98.46%Color and Shape:SolidMolecular weight:246.35Ref: TM-T11183
1mg92.00€2mg125.00€5mg170.00€10mg213.00€25mg474.00€50mg688.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)170.00€Alniditan
CAS:Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.Formula:C17H26N4OPurity:98%Color and Shape:SolidMolecular weight:302.41Ziprasidone hydrochloride monohydrate
CAS:Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychoticFormula:C21H21ClN4OS·HCl·H2OPurity:98% - 99.83%Color and Shape:Off-White PowderMolecular weight:467.12Lurasidone hydrochloride
CAS:Lurasidone HCl: Atypical antipsychotic, treats schizophrenia & bipolar, affects dopamine, serotonin & adrenergic receptors.Formula:C28H36N4O2S·HClPurity:99.51%Color and Shape:SolidMolecular weight:529.14(+)-OSU 6162
CAS:(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formula:C15H23NO2SPurity:99.81%Color and Shape:SoildMolecular weight:281.41Ref: TM-T60027
1mg77.00€5mg155.00€10mg220.00€25mg338.00€50mg472.00€100mg632.00€200mg853.00€1mL*10mM (DMSO)163.00€Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormula:C23H26ClN5O2Purity:99.8% - 99.8%Color and Shape:SolidMolecular weight:439.94Ref: TM-T21666
2mg40.00€5mg49.00€10mg64.00€25mg135.00€50mg240.00€100mg339.00€200mg439.00€500mgTo inquireSumatriptan succinate
CAS:Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.Formula:C18H27N3O6SPurity:97.53% - 99.51%Color and Shape:White PowderMolecular weight:413.49Jatrorrhizine chloride
CAS:Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.Formula:C20H20ClNO4Purity:99.79%Color and Shape:SolidMolecular weight:373.8rac Desmethyl Citalopram Hydrochloride
CAS:rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formula:C19H20ClFN2OPurity:96.14%Color and Shape:SolidMolecular weight:346.83Tegaserod
CAS:Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).Formula:C16H23N5OPurity:99.89%Color and Shape:SolidMolecular weight:301.39Lurasidone
CAS:Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6Formula:C28H36N4O2SPurity:99.5%Color and Shape:SolidMolecular weight:492.68PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Purity:98%Color and Shape:Odour SolidAlprenolol
CAS:Alprenolol (Alpheprol) is a non-selective β-adrenergic receptor (β-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1AFormula:C15H23NO2Purity:99.73% - 99.78%Color and Shape:SolidMolecular weight:249.35Mebhydrolin napadisylate
CAS:Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergicFormula:C19H20N2C10H8O6S2Purity:99.35% - 99.77%Color and Shape:White Or Almost White CrystallineMolecular weight:420.52Zacopride hydrochloride
CAS:Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.Formula:C15H20ClN3O2·HClPurity:98.32%Color and Shape:SolidMolecular weight:346.26Ref: TM-T5336
1mg46.00€5mg87.00€10mg144.00€25mg283.00€50mg454.00€100mg655.00€200mg930.00€1mL*10mM (DMSO)97.00€Protriptyline hydrochloride
CAS:Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.Formula:C19H21N·HClPurity:98.54% - 99.98%Color and Shape:SolidMolecular weight:299.84Sulamserod
CAS:Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormula:C19H28ClN3O5SPurity:98.76%Color and Shape:SolidMolecular weight:445.965-HT2 antagonist 1
CAS:5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.Formula:C22H29FN4O2Purity:99.25%Color and Shape:SolidMolecular weight:400.49Ref: TM-T12597
1mg678.00€5mg1,359.00€10mg1,833.00€25mg2,727.00€50mg3,676.00€100mg4,969.00€1mL*10mM (DMSO)1,605.00€Lumateperone
CAS:Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formula:C24H28FN3OPurity:99.77%Color and Shape:SolidMolecular weight:393.5Rilapine
CAS:Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.Formula:C22H20ClN3Purity:99% - 99.66%Color and Shape:SolidMolecular weight:361.87Masupirdine mesylate
CAS:Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological disorders such as Alzheimer's diseaseFormula:C23H32BrN3O9S3Purity:99.48%Color and Shape:SolidMolecular weight:670.61Lerisetron
CAS:Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.Formula:C18H20N4Purity:99.15%Color and Shape:SolidMolecular weight:292.38SB-200646
CAS:SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptorFormula:C15H14N4OPurity:99.61%Color and Shape:SolidMolecular weight:266.3Ref: TM-T8357
1mg97.00€2mg150.00€5mg207.00€10mg311.00€25mg525.00€50mg757.00€100mg1,035.00€1mL*10mM (DMSO)216.00€AVN 322 free base
CAS:AVN 322 free base is an orally available, selective and potent 5-HT6R antagonist for the study of neuropathic system disorders such as Alzheimer's disease (AD) and schizophrenia.Formula:C17H19N5O2SPurity:99.13%Color and Shape:SolidMolecular weight:357.435-HT2A&5-HT2C agonist-1
CAS:5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Formula:C14H20N2OPurity:98%Color and Shape:SolidMolecular weight:232.325-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formula:C24H26N4O2SMolecular weight:434.55Masupirdine free base
CAS:Masupirdine free base (SUVN-502 free base) is a 5-HT6 receptor antagonist that can be used to study neurological disorders like Alzheimer's disease.Formula:C21H24BrN3O3SPurity:97.40% - 98.67%Color and Shape:SolidMolecular weight:478.4Temanogrel
CAS:Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).Formula:C24H28N4O4Purity:99.24%Color and Shape:SolidMolecular weight:436.5Ref: TM-T17033
1mg69.00€5mg156.00€10mg225.00€25mg375.00€50mg533.00€100mg723.00€200mg938.00€1mL*10mM (DMSO)170.00€Lesopitron
CAS:Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.Formula:C15H21ClN6Purity:98.60% - 98.92%Color and Shape:SolidMolecular weight:320.82Harmine
CAS:Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.Formula:C13H12N2OPurity:98.29% - 99.92%Color and Shape:Off-White SolidMolecular weight:212.258-Hydroxy-DPAT hydrobromide
CAS:8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19.Formula:C16H26BrNOPurity:98.90% - 99.09%Color and Shape:SolidMolecular weight:328.29Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43CP94253 hydrochloride
CAS:CP94253 hydrochloride: selective 5-HT1B agonist, Ki=2 nM; less active on 5-HT1A/D/C/2 (Ki=89/49/860/1600 nM).Formula:C15H20ClN3OPurity:99.39%Color and Shape:SolidMolecular weight:293.79Ref: TM-T22689
5mg70.00€10mg96.00€25mg216.00€50mg354.00€100mg567.00€200mg787.00€1mL*10mM (DMSO)70.00€Clozapine
CAS:Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.Formula:C18H19ClN4Purity:99.91% - 99.93%Color and Shape:Yellow Crystals From Acetone-Petroleum Ether SolidMolecular weight:326.82Ref: TM-T0455
1g449.00€10mg35.00€25mg52.00€50mg70.00€100mg96.00€200mg170.00€500mg303.00€1mL*10mM (DMSO)47.00€L-694,247
CAS:L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.Formula:C20H21N5O3SPurity:98.36%Color and Shape:White SolidMolecular weight:411.48Naftopidil dihydrochloride
CAS:Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.Formula:C24H28N2O3·2HClPurity:99.76%Color and Shape:White SolidMolecular weight:465.41Phenylbiguanide
CAS:Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)Formula:C8H11N5Purity:99.54%Color and Shape:SolidMolecular weight:177.21LP-533401 hydrochloride
CAS:LP-533401 hydrochloride is a peripheral Tph inhibitor that does not cross the BBB and can be used to study periodontal disease and hepatic steatosis.Formula:C27H23ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:562.94Brexpiprazole HCl
CAS:Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.Formula:C25H27N3O2S·xHClPurity:99.05%Color and Shape:SolidMolecular weight:433.6Ref: TM-T8690
1mg131.00€5mg286.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€500mg2,688.00€1mL*10mM (DMSO)338.00€S 16924
CAS:S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful in the study of neurologic disorders.Formula:C22H24FNO4Purity:98.23% - 99.45%Color and Shape:SolidMolecular weight:385.43Methamnetamine hydrochloride
CAS:Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formula:C14H18ClNColor and Shape:SolidMolecular weight:235.75Palonosetron
CAS:Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).Formula:C19H24N2OPurity:98%Color and Shape:SolidMolecular weight:296.41Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formula:C14H15F3N6OPurity:97.63%Color and Shape:SolidMolecular weight:340.3SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purity:97.82% - 98.09%Color and Shape:SolidMolecular weight:557.085-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Formula:C21H26BrNO3Purity:98%Color and Shape:SolidMolecular weight:420.34
