5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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Hypidone hydrochloride
CAS:Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitorFormula:C18H23ClN2O2Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:334.84Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purity:99.43% - 99.62%Color and Shape:Colourless Flake Crystalline SolidMolecular weight:448.39Naratriptan
CAS:Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.Formula:C17H25N3O2SPurity:99.08%Color and Shape:SolidMolecular weight:335.47Metoclopramide hydrochloride
CAS:Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.Formula:C14H22ClN3O2·HClPurity:99.99%Color and Shape:White To Off-White PowderMolecular weight:336.26Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormula:C16H17FN2SPurity:100%Color and Shape:SolidMolecular weight:288.38pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.Formula:C10H13Cl2NO2Purity:99.08% - 99.88%Color and Shape:SolidMolecular weight:250.12Loxapine
CAS:Loxapine, a dibenzoxazepine antipsychotic, treats schizophrenia by blocking D2/D4 and serotonin receptors. Related to clozapine.Formula:C18H18ClN3OPurity:99.88%Color and Shape:Pale Yellowish Crystals From Petroleum Ether SolidMolecular weight:327.815-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Formula:C19H23ClN2O2Purity:98%Color and Shape:SolidMolecular weight:346.85Gevotroline
CAS:Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.Formula:C19H20FN3Purity:98.79%Color and Shape:SolidMolecular weight:309.385-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04GTS-21 dihydrochloride
CAS:GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.Formula:C19H20N2O2·2HClPurity:100% - 99.62%Color and Shape:SolidMolecular weight:381.3Ref: TM-T2663
5mg51.00€10mg85.00€25mg115.00€50mg144.00€100mg216.00€200mg325.00€500mg545.00€1mL*10mM (DMSO)57.00€4-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Formula:C9H13ClINColor and Shape:SolidMolecular weight:297.56Citalopram hydrobromide
CAS:Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormula:C20H22BrFN2OPurity:99.81%Color and Shape:White Crystalline PowderMolecular weight:405.304SB 204741
CAS:SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.Formula:C14H14N4OSPurity:99.83%Color and Shape:SolidMolecular weight:286.35Eletriptan hydrobromide
CAS:Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.Formula:C22H27BrN2O2SPurity:100% - 99.69%Color and Shape:Tan SolidMolecular weight:463.43Ref: TM-T0216
2mg39.00€5mg57.00€10mg70.00€25mg134.00€50mg230.00€100mg373.00€200mg555.00€1mL*10mM (DMSO)63.00€Cinitapride Hydrogen Tartrate
CAS:Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptorsFormula:C25H36N4O10Purity:98%Color and Shape:SolidMolecular weight:552.5812-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formula:C15H18N2O5Purity:98%Color and Shape:SolidMolecular weight:306.31WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Formula:C13H12FNO2Purity:99.82%Color and Shape:SolidMolecular weight:233.24Rotigotine Hydrochloride
CAS:Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.Formula:C19H26ClNOSPurity:99.53% - 99.56%Color and Shape:Almost White To White Crystalline PowderMolecular weight:351.93D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Formula:C24H29N3O2Color and Shape:SolidMolecular weight:391.506
