5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Products of "5-HT Receptor"
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Pizotifen Malate
CAS:Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.Formula:C19H21NS·C4H6O5Purity:100%Color and Shape:SolidMolecular weight:429.53Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formula:C21H24N2O4SPurity:99%Color and Shape:SolidMolecular weight:400.49Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purity:96.74%Color and Shape:SolidMolecular weight:244.2(Rac)-Norcisapride
CAS:Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Formula:C14H20ClN3O3Purity:99.13%Color and Shape:SoildMolecular weight:313.78(S)-Amisulpride
CAS:(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.Formula:C17H27N3O4SPurity:98.38%Color and Shape:SolidMolecular weight:369.48Ref: TM-T26375
1mg50.00€2mg71.00€5mg114.00€10mg178.00€25mg340.00€50mg538.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)126.00€AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formula:C14H21BrN2OColor and Shape:SolidMolecular weight:313.23Ondansetron hydrochloride dihydrate
CAS:Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.Formula:C18H19N3O·HCl·2H2OPurity:99.92%Color and Shape:White Crystal PowderMolecular weight:365.86SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:464.87Ipsapirone
CAS:Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.Formula:C19H23N5O3SPurity:99.01%Color and Shape:SolidMolecular weight:401.485-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formula:C9H14N4Color and Shape:SolidMolecular weight:178.234SB-200646A
CAS:SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Formula:C15H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:302.76Adatanserin
CAS:Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist.Formula:C21H31N5OPurity:99.17%Color and Shape:SolidMolecular weight:369.5ST1936
CAS:ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.Formula:C13H17ClN2Purity:98.00%Color and Shape:SolidMolecular weight:236.74Ref: TM-T23396
1mg47.00€5mg117.00€10mg188.00€25mg334.00€50mg497.00€100mg720.00€200mg1,008.00€1mL*10mM (DMSO)130.00€Cyproheptadine hydrochloride
CAS:Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Formula:C21H21N·HClPurity:99.88% - 99.97%Color and Shape:SolidMolecular weight:323.86Tropanserin
CAS:Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Formula:C17H23NO2Purity:99.74%Color and Shape:SolidMolecular weight:273.37Sarizotan 2HCl
CAS:Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.Formula:C22H23Cl2FN2OPurity:98.83%Color and Shape:SoildMolecular weight:421.345-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Formula:C19H22FNO2Purity:98%Color and Shape:SolidMolecular weight:315.38Sulamserod hydrochloride
CAS:Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formula:C19H29Cl2N3O5SColor and Shape:SolidMolecular weight:482.42LY 344864
CAS:LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Formula:C23H24O6Purity:98.55% - 99.08%Color and Shape:SolidMolecular weight:396.43WAY 163909
CAS:WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).Formula:C14H18N2Purity:98%Color and Shape:SolidMolecular weight:214.315-HT7 agonist 1
CAS:5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).Formula:C19H20ClN3Purity:98.61%Color and Shape:SolidMolecular weight:325.84Ref: TM-T10170
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)255.00€YM-31636 free base
CAS:YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.Formula:C14H11N3SColor and Shape:SolidMolecular weight:253.325-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Formula:C19H22N2O2Purity:98%Color and Shape:SolidMolecular weight:310.39Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purity:99.55% - 99.55%Color and Shape:White To Off-White SolidMolecular weight:407.0425N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Color and Shape:SolidMolecular weight:382.84Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Formula:C18H19FN2O3SPurity:97.50% - 99.33%Color and Shape:SolidMolecular weight:362.42Venlafaxine hydrochloride
CAS:Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.Formula:C17H28ClNO2Purity:99.86%Color and Shape:White Crystalline PowderMolecular weight:313.863Adatanserin hydrochloride
CAS:Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formula:C21H32ClN5OPurity:99.64%Color and Shape:SolidMolecular weight:405.96Olopatadine hydrochloride
CAS:Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Formula:C21H23NO3·HClPurity:99.62% - 99.64%Color and Shape:White SolidMolecular weight:373.87Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37SR 57227 hydrochloride
CAS:SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Formula:C10H14ClN3·HClPurity:99.89%Color and Shape:SolidMolecular weight:248.15Ref: TM-T23394
5mg50.00€10mg74.00€25mg126.00€50mg210.00€100mg313.00€200mg445.00€1mL*10mM (DMSO)49.00€RS 56812 hydrochloride
CAS:5-HT3 partial agonistFormula:C18H22ClN3O2Purity:97.69%Color and Shape:SolidMolecular weight:347.84N-Desmethyl Pimavanserin
CAS:N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formula:C24H32FN3O2Purity:98.02%Color and Shape:SolidMolecular weight:413.53Urapidil
CAS:Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.Formula:C20H29N5O3Purity:100% - 99.85%Color and Shape:SolidMolecular weight:387.48Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.77%Color and Shape:SolidMolecular weight:359.47Pizotifen
CAS:Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.Formula:C19H21NSPurity:99.93%Color and Shape:SolidMolecular weight:295.44Ondansetron
CAS:Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.Formula:C18H19N3OPurity:99.92%Color and Shape:White To Yellow CrystalsMolecular weight:293.364-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Olanzapine
CAS:Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formula:C17H20N4SPurity:100% - ≥95%Color and Shape:Yellowish Crystalline PowderMolecular weight:312.43Desvenlafaxine succinate hydrate
CAS:Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).Formula:C20H33NO7Purity:99.26%Color and Shape:White Crystalline PowdeMolecular weight:399.48Dolasetron Mesylate hydrate
CAS:Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Formula:C20H26N2O7SPurity:99.86% - 99.9%Color and Shape:SolidMolecular weight:438.49cis-(Z)-Flupentixol dihydrochloride
CAS:cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Formula:C23H27Cl2F3N2OSPurity:98.07%Color and Shape:SolidMolecular weight:507.44Ebalzotan
CAS:NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.Formula:C19H30N2O2Purity:99.08% - 99.41%Color and Shape:SolidMolecular weight:318.45Relenopride
CAS:YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.Formula:C24H30ClFN4O4Purity:98.91% - 99.20%Color and Shape:SoildMolecular weight:492.97MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Formula:C19H29Cl2N3O3Purity:100.00%Color and Shape:SolidMolecular weight:418.36Ref: TM-T23007
1mg86.00€5mg157.00€10mg215.00€25mg472.00€50mg687.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)281.00€AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormula:C10H13N3OPurity:99.77%Color and Shape:SolidMolecular weight:191.23Naluzotan hydrochloride
CAS:Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 nM, Ki: ~5.1 nM), is used in anxiety and depression studies.Formula:C23H39ClN4O3SPurity:98.61%Color and Shape:SolidMolecular weight:487.1PNU 22394 hydrochloride
CAS:PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonistFormula:C13H17ClN2Purity:97.83%Color and Shape:SolidMolecular weight:236.74RS-67333
CAS:RS-67333 is a partial agonist of 5-HT4R with neuroprotective effects.Formula:C19H29ClN2O2Purity:99.24%Color and Shape:SolidMolecular weight:352.9(E)-3,4,5-Trimethoxycinnamic acid
CAS:(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.Formula:C12H14O5Purity:99.83%Color and Shape:SolidMolecular weight:238.24Clovoxamine
CAS:Clovoxamine fumarate (DU 23811 fumarate) is a 5-HT reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activity.Formula:C14H21ClN2O2Purity:98.88% - 99.16%Color and Shape:SolidMolecular weight:284.78Mosapride
CAS:Mosapride (AS-4370) is a selective 5HT4 agonistFormula:C21H25ClFN3O3Purity:99.56%Color and Shape:White To Off-White Crystalline SolidMolecular weight:421.89SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Formula:C28H31ClN4O4Purity:98.40% - 99.23%Color and Shape:SolidMolecular weight:523.02Lafutidine
CAS:Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.Formula:C22H29N3O4SPurity:99.94%Color and Shape:Yellowish White Crystalline PowderMolecular weight:431.55Vilazodone
CAS:Vilazodone (SB659746A): an SSRI and 5-HT-1A agonist, boosts serotonin to treat depression and anxiety.Formula:C26H27N5O2Purity:99.61%Color and Shape:Light Yellow SolidMolecular weight:441.52Agomelatine (L(+)-Tartaric acid)
CAS:Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, andFormula:C19H23NO8Color and Shape:SolidMolecular weight:393.39LP-211
CAS:LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.Formula:C30H34N4OPurity:98.65%Color and Shape:SolidMolecular weight:466.62Ref: TM-T5387
2mg47.00€5mg70.00€10mg96.00€25mg180.00€50mg305.00€100mg487.00€200mg695.00€1mL*10mM (DMSO)77.00€Usmarapride free base
CAS:Usmarapride free base (SUVN-D4010 free base) is a partial agonist of 5-HT4 receptors, used in Alzheimer's disease research.Formula:C21H29N5O2Purity:99.91% - 99.91%Color and Shape:SolidMolecular weight:383.49Glemanserin
CAS:Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.Formula:C20H25NOPurity:99.52%Color and Shape:SolidMolecular weight:295.42Ref: TM-T22964
1mg40.00€5mg88.00€10mg126.00€25mg273.00€50mg432.00€100mg638.00€500mg1,359.00€1mL*10mM (DMSO)88.00€DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99% - 99.89%Color and Shape:SolidMolecular weight:443.37Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Formula:C16H19NOPurity:99.12%Color and Shape:SolidMolecular weight:241.33Ref: TM-T67956
1mg97.00€5mg217.00€10mg325.00€25mg557.00€50mg797.00€100mg1,103.00€500mg2,205.00€1mL*10mM (DMSO)188.00€RG-12915
CAS:RG-12915 is a selective antagonist of 5-HT3(IC50 value of 0.16 nM).Formula:C20H25ClN2O2Purity:98%Color and Shape:SolidMolecular weight:360.88VUF 10166
CAS:VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.Formula:C13H15ClN4Purity:99.66%Color and Shape:SolidMolecular weight:262.74Trazodone hydrochloride
CAS:Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent.Formula:C19H23Cl2N5OPurity:99.50% - 99.52%Color and Shape:SolidMolecular weight:408.335-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFormula:C17H22F2N6OPurity:98%Color and Shape:SolidMolecular weight:364.39Cariprazine
CAS:Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderateFormula:C21H32Cl2N4OPurity:99.68% - 99.87%Color and Shape:SolidMolecular weight:427.41Ref: TM-T4577
1mg51.00€5mg108.00€10mg180.00€25mg316.00€50mg472.00€100mg658.00€200mg938.00€1mL*10mM (DMSO)108.00€Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:99.11% - 99.13%Color and Shape:SolidMolecular weight:233.35Cyamemazine
CAS:Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Formula:C19H21N3SPurity:97.01%Color and Shape:SolidMolecular weight:323.46Ziprasidone hydrochloride
CAS:Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychoticFormula:C21H22CL2N4OSPurity:97.97% - 99.82%Color and Shape:SolidMolecular weight:449.4p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purity:99.78%Color and Shape:SolidMolecular weight:507.43Citalopram
CAS:Citalopram (Lu 10-171), a serotonin and 5-HT reuptake inhibitor.Citalopram has antidepressant activity and may be used to study dementia.Formula:C20H21FN2OPurity:99.89%Color and Shape:SolidMolecular weight:324.39AGH-107
CAS:AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.Formula:C13H12IN3Color and Shape:SolidMolecular weight:337.162-Methyl-5-HT
CAS:2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H14N2OPurity:95.64%Color and Shape:SolidMolecular weight:190.24Ref: TM-T10075
5mg50.00€10mg88.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)52.00€Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.845HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Formula:C20H22BrN3O2SPurity:98.48% - 98.95%Color and Shape:SolidMolecular weight:448.38Remlifanserin
CAS:Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).Formula:C24H29F2N3O2Color and Shape:SolidMolecular weight:429.50S 14506 hydrochloride
CAS:S 14506 hydrochloride is a 5-HT1A receptor full agonist.Formula:C24H27ClFN3O2Purity:99.5%Color and Shape:SolidMolecular weight:443.945-HT3 antagonist 2
CAS:5-HT3 antagonist 2 is an antagonist of 5-HT3 receptor.Formula:C18H21N3OPurity:98%Color and Shape:SolidMolecular weight:295.38Ocaperidone
CAS:Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.Formula:C24H25FN4O2Purity:99.33%Color and Shape:SolidMolecular weight:420.484-hydroxy DiPT hydrochloride
CAS:4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.Formula:C16H25ClN2OColor and Shape:SolidMolecular weight:296.84Renzapride
CAS:Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist used in the study of irritable bowel syndrome.Formula:C16H22ClN3O2Purity:98.97% - 99.09%Color and Shape:SolidMolecular weight:323.82GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Formula:C25H28N4O2Purity:99.76%Color and Shape:SolidMolecular weight:416.52Ref: TM-T8737
1mg43.00€2mg56.00€5mg88.00€10mg119.00€25mg235.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)87.00€Pardoprunox hydrochloride
CAS:Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1)Formula:C12H16ClN3O2Purity:98.73% - 99.13%Color and Shape:SolidMolecular weight:269.73LY266097 hydrochloride
CAS:LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression research.Formula:C21H24Cl2N2O2Purity:99.63%Color and Shape:SolidMolecular weight:407.33Alosetron hydrochloride
CAS:Alosetron hydrochloride (GR 68755), a selective 5-HT3 receptor antagonist, can block the actions of serotonin at 5-HT3 sites in the peripheral nervous system.Formula:C17H19ClN4OPurity:99.90%Color and Shape:Off-White PowderMolecular weight:330.81(Rac)-WAY-161503
CAS:(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.Formula:C11H11Cl2N3OPurity:98.08%Color and Shape:SolidMolecular weight:272.13Org-13011 fumarate
CAS:Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.Formula:C22H29F3N4O5Purity:98.61%Color and Shape:SolidMolecular weight:486.48Azaphen dihydrochloride monohydrate
CAS:Azaphen dihydrochloride monohydrate is a 5-hydroxytryptamine reabsorption inhibitor with antidepressant activity and can be used to study neurological diseases.Formula:C16H23Cl2N5O2Purity:99.85%Color and Shape:SolidMolecular weight:388.29Metadoxine
CAS:Metadoxine (Metadoxil) is a neurotransmitter stimulant.Formula:C8H11NO3·C5H7NO3Purity:99.19%Color and Shape:Off-White PowderMolecular weight:298.29Geissoschizine methyl ether
CAS:Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.Formula:C22H26N2O3Purity:99.68% - 99.86%Color and Shape:SolidMolecular weight:366.45Ref: TM-TN1032
1mg137.00€5mg404.00€10mg587.00€25mg914.00€50mg1,225.00€100mg1,663.00€1mL*10mM (DMSO)375.00€Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Formula:C22H28FNO3Purity:98.94% - 99.95%Color and Shape:SolidMolecular weight:373.46Methiothepin maleate
CAS:Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.Formula:C24H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:472.62Tianeptine
CAS:Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂,具有抗抑郁、抗焦虑和神经保护作用,可用于缓解疼痛的研究。Formula:C21H25ClN2O4SPurity:99.04%Color and Shape:SolidMolecular weight:436.95SB 271046 hydrochloride
CAS:SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist and is > 200-fold selective over 55 other receptors, enzymes and ion channels.Formula:C20H22ClN3O3S2·HClPurity:99.57%Color and Shape:SolidMolecular weight:488.455-Methyltryptamine hydrochloride
CAS:5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.Formula:C11H15ClN2Purity:99.45%Color and Shape:SolidMolecular weight:210.703Dolasetron
CAS:Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.Formula:C19H20N2O3Purity:99.84% - 99.86%Color and Shape:White PowderMolecular weight:324.37Harmine hydrochloride
CAS:Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.Formula:C13H13ClN2OPurity:100% - 99.45%Color and Shape:Yellow To Slightly Green Crystalline PowderMolecular weight:248.71Almotriptan Malate
CAS:Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55A-582941 dihydrochloride
CAS:A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partialFormula:C17H22Cl2N4Purity:99.55%Color and Shape:SolidMolecular weight:353.29Ref: TM-T22016
1mg42.00€5mg88.00€10mg120.00€25mg235.00€50mg354.00€100mg533.00€200mg743.00€1mL*10mM (DMSO)87.00€ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColor and Shape:SolidMolecular weight:335.44AC-90179 HCl
CAS:AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.Formula:C23H31ClN2O2Purity:99.14%Color and Shape:SolidMolecular weight:402.96Ref: TM-T26543
1mg52.00€2mg74.00€5mg96.00€10mg137.00€25mg215.00€50mg391.00€100mg582.00€1mL*10mM (DMSO)127.00€Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formula:C16H20ClNOPurity:98.98% - 99.19%Color and Shape:SoildMolecular weight:277.79Ref: TM-T67956L
1mg97.00€5mg217.00€10mg325.00€25mg557.00€50mg797.00€100mg1,103.00€1mL*10mM (DMSO)208.00€Asenapine Maleate
CAS:Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually.Formula:C21H20ClNO5Purity:99.28%Color and Shape:SolidMolecular weight:401.84Ref: TM-T1951
5mg35.00€10mg51.00€25mg80.00€50mg96.00€100mg135.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)55.00€RS-127445
CAS:RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.Formula:C17H16FN3Purity:99.32%Color and Shape:SolidMolecular weight:281.33AVN-492
CAS:AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).Formula:C17H21N5O2SPurity:99.81%Color and Shape:SolidMolecular weight:359.45Ref: TM-T5179
1mg39.00€2mg49.00€5mg81.00€10mg120.00€25mg236.00€50mg354.00€100mg510.00€1mL*10mM (DMSO)89.00€Befiradol hydrochloride
CAS:Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formula:C20H23Cl2F2N3OPurity:99.1%Color and Shape:SolidMolecular weight:430.32Levodropropizine
CAS:Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.Formula:C13H20N2O2Purity:100% - 99.93%Color and Shape:White Or Off White Crystalline PowderMolecular weight:236.31R 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurity:98.55%Color and Shape:SolidMolecular weight:459.58AVN-322
CAS:AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment.Formula:C17H20ClN5O2SPurity:98.83%Color and Shape:SolidMolecular weight:393.89BW 723C86
CAS:BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.Formula:C16H19ClN2OSPurity:99.35%Color and Shape:SolidMolecular weight:322.85Pardoprunox
CAS:Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Formula:C12H15N3O2Purity:98%Color and Shape:SolidMolecular weight:233.27CI 169369
CAS:CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.Formula:C19H21ClN2SPurity:100%Color and Shape:SoildMolecular weight:344.9Paroxetine hydrochloride
CAS:Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formula:C19H21ClFNO3Purity:98% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:365.8265-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5Cannabidiolic acid methyl ester
CAS:Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formula:C23H32O4Color and Shape:SolidMolecular weight:372.5Nefazodone hydrochloride
CAS:Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.Formula:C25H33Cl2N5O2Purity:99% - 99.86%Color and Shape:White SolidMolecular weight:506.47Ref: TM-T3275
5mg47.00€10mg70.00€25mg120.00€50mg216.00€100mg325.00€200mg472.00€500mg775.00€1mL*10mM (DMSO)77.00€LY334370
CAS:LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nMFormula:C21H22FN3OPurity:99.32%Color and Shape:SolidMolecular weight:351.42CJ 033466
CAS:CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.Formula:C19H28ClN5OPurity:98.41%Color and Shape:SolidMolecular weight:377.91Ref: TM-T22671
1mg48.00€5mg101.00€10mg170.00€25mg270.00€50mg386.00€100mg520.00€1mL*10mM (DMSO)158.00€4-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.28Intepirdine
CAS:Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.Formula:C19H19N3O2SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:353.44Lesopitron HCl
CAS:Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.Formula:C15H22Cl2N6Purity:97.05% - 98.18%Color and Shape:SoildMolecular weight:357.28Minesapride
CAS:Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.Formula:C21H31ClN4O5Purity:99% - 99.35%Color and Shape:SolidMolecular weight:454.95Ref: TM-T28043L
1mg115.00€5mg245.00€10mg363.00€25mg562.00€50mg802.00€100mg1,111.00€200mg1,491.00€1mL*10mM (DMSO)284.00€LP44 hydrochloride
CAS:LP44 hydrochloride is a 5-HT7 agonist with analgesic effects on formalin-induced orofacial pain in mice and can be used to study neuroinflammation.Formula:C27H38ClN3OSPurity:98.06%Color and Shape:SolidMolecular weight:488.13Methiothepin mesylate
CAS:Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.Formula:C21H28N2O3S3Purity:98% - 99.92%Color and Shape:SolidMolecular weight:452.65Pheniramine maleate
CAS:Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formula:C16H20N2·C4H4O4Purity:99.85%Color and Shape:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CMolecular weight:356.42Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Formula:C16H20N2O2SColor and Shape:SolidMolecular weight:304.41Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formula:C22H23N3O3SPurity:98.60%Color and Shape:SolidMolecular weight:409.5Ref: TM-T30798
1mg81.00€5mg170.00€10mg274.00€25mg543.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)198.00€SEP-363856 hydrochloride
CAS:SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.Formula:C9H14ClNOSPurity:99.86% - 99.99%Color and Shape:SolidMolecular weight:219.73Ref: TM-T12899L
1mg70.00€2mg92.00€5mg154.00€10mg243.00€25mg425.00€50mg628.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)169.00€AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColor and Shape:SolidMolecular weight:268.78Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.23% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg145.00€2mg215.00€5mg314.00€10mg474.00€25mg808.00€50mg1,111.00€100mg1,501.00€1mL*10mM (DMSO)324.00€Serotonin
CAS:Serotonin (5-hydroxytryptamine) is a natural product from animalsFormula:C10H12N2OPurity:95.94% - 99.92%Color and Shape:SolidMolecular weight:176.22Ref: TM-TN2437
1mg78.00€5mg139.00€10mg202.00€25mg360.00€50mg540.00€100mg810.00€500mg1,596.00€1mL*10mM (DMSO)117.00€m-Chlorophenylbiguanide hydrochloride
CAS:m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.Formula:C8H11Cl2N5Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:248.11Viloxazine
CAS:Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFormula:C13H19NO3Purity:99.8%Color and Shape:SolidMolecular weight:237.29Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formula:C17H18F3NOPurity:99.07% - 99.28%Color and Shape:SolidMolecular weight:309.332-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Bromperidol
CAS:Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.Formula:C21H23BrFNO2Purity:99.89%Color and Shape:Tan SolidMolecular weight:420.32Cinitapride
CAS:Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.Formula:C21H30N4O4Purity:98.99%Color and Shape:SolidMolecular weight:402.49Ref: TM-T21385
1mg78.00€5mg163.00€10mg253.00€25mg505.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)187.00€p-MPPF
CAS:p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H27FN4O2Purity:99.79%Color and Shape:SolidMolecular weight:434.51Mirtazapine
CAS:Mirtazapine is a unique tetracyclic antidepressant, may cause temporary liver enzyme elevation, and is linked to rare liver injury.Formula:C17H19N3Purity:99.98%Color and Shape:SolidMolecular weight:265.35PRX933 hydrochloride
CAS:PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Formula:C16H22ClN5O2Purity:97.99% - 99.72%Color and Shape:SolidMolecular weight:351.84Ref: TM-T12565
1mg356.00€5mg568.00€10mg907.00€25mg1,339.00€50mg1,815.00€100mg2,432.00€1mL*10mM (DMSO)652.00€Iprindole
CAS:Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].Formula:C19H28N2Purity:99.06%Color and Shape:SolidMolecular weight:284.44Ref: TM-T37015
2mg37.00€5mg52.00€10mg80.00€25mg154.00€50mg266.00€100mg455.00€200mg652.00€1mL*10mM (DMSO)84.00€MDL 100009
CAS:MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Formula:C22H28FNO3Purity:98.96%Color and Shape:SolidMolecular weight:373.46Ref: TM-T22359
1mg148.00€2mg188.00€5mg283.00€10mg424.00€25mg655.00€50mg883.00€100mg1,169.00€200mg1,596.00€1mL*10mM (DMSO)335.00€Tropisetron
CAS:Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Formula:C17H20N2O2Purity:99.95%Color and Shape:White SolidMolecular weight:284.35Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Formula:C22H33FN2O2Color and Shape:SolidMolecular weight:376.51GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formula:C23H27N3O2Purity:99.9%Color and Shape:SolidMolecular weight:377.48Sertindole
CAS:Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formula:C24H26ClFN4OPurity:99.74%Color and Shape:Off-White To Pale Yellow SolidMolecular weight:440.94Xanthotoxol
CAS:Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.Formula:C11H6O4Purity:99.97%Color and Shape:SolidMolecular weight:202.16SKF-83566
CAS:SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Formula:C17H18BrNOPurity:95.00% - 99.82%Color and Shape:SolidMolecular weight:332.23Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Color and Shape:White SolidMolecular weight:371.54Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFormula:C25H25Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:502.395-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFormula:C19H23ClFNO2Purity:98%Color and Shape:SolidMolecular weight:351.84Puerarin
CAS:Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.Formula:C21H20O9Purity:98.90% - 99.21%Color and Shape:Yellow Brown Fine PowderMolecular weight:416.38Cilansetron
CAS:Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.Formula:C20H21N3OPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:319.4Clothiapine
CAS:Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.Formula:C18H18ClN3SPurity:99.93%Color and Shape:SolidMolecular weight:343.87GSK163090
CAS:GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).Formula:C25H29N5OPurity:99.20%Color and Shape:SolidMolecular weight:415.53Ref: TM-TQ0311
1mg37.00€2mg52.00€5mg80.00€10mg125.00€25mgTo inquire50mgTo inquire1mL*10mM (DMSO)87.00€JPC0323
JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequateFormula:C22H43NO4Purity:98%Color and Shape:SolidMolecular weight:385.585-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formula:C24H25N5OColor and Shape:SolidMolecular weight:399.49Risperidone
CAS:Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.Formula:C23H27FN4O2Purity:99.73%Color and Shape:Crystalline SolidMolecular weight:410.48MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosisFormula:C20H26IN5O3Purity:98%Color and Shape:SolidMolecular weight:511.36Escin IB
CAS:Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, toFormula:C55H86O24Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:1131.26Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurity:99.76%Color and Shape:SolidMolecular weight:523.75Ref: TM-T8946
1mg58.00€5mg111.00€10mg170.00€25mg284.00€50mg393.00€100mg552.00€200mg748.00€1mL*10mM (DMSO)129.00€Pipamperone
CAS:Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.Formula:C21H30FN3O2Purity:99.94%Color and Shape:White PowderMolecular weight:375.48Ref: TM-T12480
1mg62.00€2mg85.00€5mg119.00€10mg170.00€25mg283.00€50mg430.00€100mg622.00€1mL*10mM (DMSO)131.00€WAY208466 dihydrochloride
CAS:WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.Formula:C17H20Cl2FN3O2SPurity:98.43%Color and Shape:SolidMolecular weight:420.33WAY-100635 maleate
CAS:WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).Formula:C25H34N4O2·xC4H4O4Purity:100%Color and Shape:White SolidMolecular weight:538.645Ref: TM-T3453
2mg46.00€5mg66.00€10mg95.00€25mg159.00€50mg226.00€100mg334.00€500mg807.00€1mL*10mM (DMSO)79.00€5-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Color and Shape:SolidMolecular weight:325.36Niaprazine
CAS:Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.Formula:C20H25FN4OPurity:99.5%Color and Shape:SolidMolecular weight:356.44Ref: TM-T36949
2mg40.00€5mg58.00€10mg96.00€25mg144.00€50mg210.00€100mg309.00€200mg444.00€1mL*10mM (DMSO)64.00€Brexpiprazole
CAS:Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.Formula:C25H27N3O2SPurity:99.06% - 99.96%Color and Shape:SolidMolecular weight:433.57SB 243213
CAS:SB 243213 is a 5-HT2C receptor antagonist with anxiolytic and antidepressant activity used in schizophrenia and movement disorders.Formula:C22H19F3N4O2Purity:100% - 100%Color and Shape:SolidMolecular weight:428.41Bemesetron
CAS:Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.Formula:C15H17Cl2NO2Purity:97.37%Color and Shape:SolidMolecular weight:314.21Prucalopride
CAS:Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.Formula:C18H26ClN3O3Purity:100%Color and Shape:SolidMolecular weight:367.87Ro4368554
CAS:Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.Formula:C19H21N3O2SColor and Shape:SolidMolecular weight:355.454lumateperone Tosylate
CAS:lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist, a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors.Formula:C31H36FN3O4SPurity:95.83% - 98.57%Color and Shape:SolidMolecular weight:565.7F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Formula:C21H25ClF2N4OPurity:99.09%Color and Shape:SolidMolecular weight:422.9FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurity:98%Color and Shape:SolidMolecular weight:256.27SB 242084
CAS:SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.Formula:C21H19ClN4O2Purity:99.77% - ≥98%Color and Shape:SolidMolecular weight:394.85Ref: TM-T7277
1mg42.00€2mg55.00€5mg90.00€10mg115.00€25mg246.00€50mg472.00€100mg720.00€1mL*10mM (DMSO)89.00€Cisapride
CAS:Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.Formula:C23H29ClFN3O4Purity:99.77%Color and Shape:White To Slightly Biege Powder SolidMolecular weight:465.95Ref: TM-T1291
5mg47.00€10mg59.00€25mg77.00€50mg99.00€100mg135.00€200mg235.00€500mg394.00€1mL*10mM (DMSO)55.00€(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Formula:C15H19F2N3OPurity:98%Color and Shape:SolidMolecular weight:295.33Frovatriptan succinate hydrate
CAS:Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.Formula:C18H25N3O6Purity:99.95%Color and Shape:SolidMolecular weight:379.41Hypidone hydrochloride
CAS:Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitorFormula:C18H23ClN2O2Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:334.84Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purity:99.43% - 99.62%Color and Shape:Colourless Flake Crystalline SolidMolecular weight:448.39Naratriptan
CAS:Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.Formula:C17H25N3O2SPurity:99.08%Color and Shape:SolidMolecular weight:335.47Metoclopramide hydrochloride
CAS:Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.Formula:C14H22ClN3O2·HClPurity:99.99%Color and Shape:White To Off-White PowderMolecular weight:336.26Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormula:C16H17FN2SPurity:100%Color and Shape:SolidMolecular weight:288.38pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.Formula:C10H13Cl2NO2Purity:99.08% - 99.88%Color and Shape:SolidMolecular weight:250.12Loxapine
CAS:Loxapine, a dibenzoxazepine antipsychotic, treats schizophrenia by blocking D2/D4 and serotonin receptors. Related to clozapine.Formula:C18H18ClN3OPurity:99.88%Color and Shape:Pale Yellowish Crystals From Petroleum Ether SolidMolecular weight:327.815-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Formula:C19H23ClN2O2Purity:98%Color and Shape:SolidMolecular weight:346.85Gevotroline
CAS:Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.Formula:C19H20FN3Purity:98.79%Color and Shape:SolidMolecular weight:309.385-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04GTS-21 dihydrochloride
CAS:GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.Formula:C19H20N2O2·2HClPurity:100% - 99.62%Color and Shape:SolidMolecular weight:381.3Ref: TM-T2663
5mg51.00€10mg85.00€25mg115.00€50mg144.00€100mg216.00€200mg325.00€500mg545.00€1mL*10mM (DMSO)57.00€4-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Formula:C9H13ClINColor and Shape:SolidMolecular weight:297.56Citalopram hydrobromide
CAS:Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormula:C20H22BrFN2OPurity:99.81%Color and Shape:White Crystalline PowderMolecular weight:405.304SB 204741
CAS:SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.Formula:C14H14N4OSPurity:99.83%Color and Shape:SolidMolecular weight:286.35Eletriptan hydrobromide
CAS:Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.Formula:C22H27BrN2O2SPurity:100% - 99.69%Color and Shape:Tan SolidMolecular weight:463.43Ref: TM-T0216
2mg39.00€5mg57.00€10mg70.00€25mg134.00€50mg230.00€100mg373.00€200mg555.00€1mL*10mM (DMSO)63.00€Cinitapride Hydrogen Tartrate
CAS:Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptorsFormula:C25H36N4O10Purity:98%Color and Shape:SolidMolecular weight:552.5812-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formula:C15H18N2O5Purity:98%Color and Shape:SolidMolecular weight:306.31WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Formula:C13H12FNO2Purity:99.82%Color and Shape:SolidMolecular weight:233.24Rotigotine Hydrochloride
CAS:Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.Formula:C19H26ClNOSPurity:99.53% - 99.56%Color and Shape:Almost White To White Crystalline PowderMolecular weight:351.93D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Formula:C24H29N3O2Color and Shape:SolidMolecular weight:391.506
