Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Pranoprofen
CAS:Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.Formula:C15H13NO3Purity:97.98% - 99.88%Color and Shape:SolidMolecular weight:255.27Piroxicam
CAS:Piroxicam (CP-16171) is a non-specific COX inhibitor.Formula:C15H13N3O4SPurity:99.52%Color and Shape:SolidMolecular weight:331.35Nifenazone
CAS:Nifenazone (Nicodone) is a pyrazole drug, used in the in the treatment of rheumatic disorders.Formula:C17H16N4O2Purity:99.74%Color and Shape:SolidMolecular weight:308.33Imatinib
CAS:Formula:C29H31N7OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:493.62TFAP
CAS:TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitorFormula:C13H10F3N3OPurity:99.87%Color and Shape:SolidMolecular weight:281.23Firocoxib
CAS:Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.Formula:C17H20O5SPurity:99.84%Color and Shape:SolidMolecular weight:336.4[10]-Shogaol
CAS:[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.Formula:C21H32O3Purity:97.64% - 99.79%Color and Shape:SolidMolecular weight:332.48Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate
CAS:Formula:C15H17NaO3Purity:97%Color and Shape:SolidMolecular weight:268.28345000000016,11-Dihydro-11-oxodibenzo[b,e]oxepin-2-acetic Acid
CAS:Formula:C16H12O4Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:268.27Anti-inflammatory agent 53
Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrestFormula:C24H22N2O4SPurity:98%Color and Shape:SolidMolecular weight:434.51α-Spinasterol
CAS:α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.Formula:C29H48OPurity:99.58% - 99.58%Color and Shape:SolidMolecular weight:412.69Canolol
CAS:Canolol (Phenol, 4-ethenyl-2,6-dimethoxy-) is an antioxidant phenolic compound that has potential use as a COX-2 inhibitor.Formula:C10H12O3Purity:99.39%Color and Shape:SolidMolecular weight:180.2Propyphenazone
CAS:Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.Formula:C14H18N2OPurity:99.64%Color and Shape:SolidMolecular weight:230.31SC58451
CAS:SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.Formula:C20H19FO2SPurity:100%Color and Shape:SolidMolecular weight:342.43Eicosatetraynoic acid
CAS:ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).Formula:C20H24O2Purity:98%Color and Shape:SolidMolecular weight:296.4PD 153035 Hydrochloride
CAS:Formula:C16H14BrN3O2·HClPurity:>97.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:396.67Indomethacin farnesil
CAS:Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.Formula:C34H40ClNO4Purity:99.84%Color and Shape:SolidMolecular weight:562.14
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