Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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3-Methylsalicylic acid
CAS:3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties,which reduces plasma free fatty acid levels.Formula:C8H8O3Purity:97.36%Color and Shape:SolidMolecular weight:152.15Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formula:C20H17FO3SPurity:99.09% - 99.15%Color and Shape:Yellow SolidMolecular weight:356.41Veratric acid
CAS:Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-Formula:C9H10O4Purity:99.44%Color and Shape:SolidMolecular weight:182.17S-(+)-Ketoprofen
CAS:S-(+)-Ketoprofen, an NSAID, blocks cyclo-oxygenase to reduce pain and inflammation. Sold as Keral, Miracox, Enantyum, and Dolmen in various regions.Formula:C16H14O3Purity:99.44%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:254.282-[5-(Phenylcarbonyl)-2-thienyl]propanoic acid
CAS:Formula:C14H12O3SPurity:98%Color and Shape:SolidMolecular weight:260.3083Trometamol
CAS:Controlled ProductTrometamol: treats acidemia, blocks COX1/COX2, inhibits pro-inflammatory prostaglandins.Formula:C4H11NO3Purity:99.05%Color and Shape:White Solid CrystallineMolecular weight:121.14Antioxidant agent-15
CAS:Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.Formula:C19H14O2Purity:98%Color and Shape:SolidMolecular weight:274.31SC-58125
CAS:SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.Formula:C17H12F4N2O2SPurity:99.57%Color and Shape:SolidMolecular weight:384.35Ref: TM-T23333
5mg39.00€10mg64.00€25mg126.00€50mg188.00€100mg319.00€200mg455.00€1mL*10mM (DMSO)58.00€indomethacin farnesil
CAS:Formula:C34H40ClNO4Purity:98%Color and Shape:SolidMolecular weight:562.1387COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41Tyrphostin AG 1478
CAS:Formula:C16H14ClN3O2Purity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:315.76BN-82451 2HCl
CAS:BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.Formula:C18H28Cl2N2OSPurity:98.55% - 99.84%Color and Shape:SolidMolecular weight:391.4Salicylamide
CAS:Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin.Formula:C7H7NO2Purity:99.96%Color and Shape:White Solid CrystallineMolecular weight:137.14Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Formula:C16H14O3Purity:98.35% - 98.46%Color and Shape:White SolidMolecular weight:254.28Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Formula:C21H19NO3SPurity:97.98% - 99.13%Color and Shape:SolidMolecular weight:365.45Ref: TM-T1867
2mg40.00€5mg60.00€10mg87.00€25mg170.00€50mg274.00€100mg439.00€500mg938.00€1mL*10mM (DMSO)66.00€Mavacoxib
CAS:Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.Formula:C16H11F4N3O2SPurity:99.90%Color and Shape:SolidMolecular weight:385.34(αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
CAS:Formula:C14H14O3Purity:98%Color and Shape:SolidMolecular weight:230.25924-Hydroxyantipyrine
CAS:4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.Formula:C11H12N2O2Purity:99.85%Color and Shape:SolidMolecular weight:204.23Timegadine hydrochloride
CAS:Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.Formula:C20H24ClN5SColor and Shape:SolidMolecular weight:401.96Isoorientin
CAS:Isoorientin (Homoorientin) has antioxidant activity.Formula:C21H20O11Purity:98.84% - 99.48%Color and Shape:SolidMolecular weight:448.38Ref: TM-T6S0722
1mg38.00€5mg84.00€10mg119.00€25mg235.00€50mg376.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)92.00€
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