Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Antipyrine
CAS:Antipyrine, an analgesic/antipyretic, used orally or as ear drops, tests liver enzyme response to diseases/drugs.Formula:C11H12N2OPurity:99.77%Color and Shape:SolidMolecular weight:188.23N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.69%Color and Shape:SolidMolecular weight:177.24Nimesulide
CAS:Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.Formula:C13H12N2O5SPurity:98% - 99.91%Color and Shape:Yellow Needle-Like CrystalsMolecular weight:308.31Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purity:99.57%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:170.12Losartan Carboxaldehyde
CAS:Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.Formula:C22H21ClN6OPurity:99.10%Color and Shape:SolidMolecular weight:420.89Resveratrol
CAS:Formula:C14H12O3Purity:>99.0%(GC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:228.25COX-2-IN-31
COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).Formula:C17H16N6O4SPurity:98%Color and Shape:SolidMolecular weight:400.41(S)-Flurbiprofen
CAS:Esflurbiprofen is an inhibitor of COX-1 and COX-2.Formula:C15H13FO2Purity:99.99%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:244.26(+/-)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID
CAS:Formula:C14H14O3Purity:98%Color and Shape:SolidMolecular weight:230.25915999999998COX-2-IN-1
CAS:COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).Formula:C18H14ClF3N4O2SPurity:100%Color and Shape:SolidMolecular weight:442.84Ref: TM-T10033
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)283.00€Lornoxicam
CAS:Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, andFormula:C13H10ClN3O4S2Purity:99.41% - 99.53%Color and Shape:Crystalline SolidMolecular weight:371.82Tilmacoxib
CAS:Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).Formula:C16H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:338.4Diclofenac Sodium Salt
CAS:Formula:C14H10Cl2NNaO2Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:318.13Iguratimod
CAS:Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).Formula:C17H14N2O6SPurity:99.93%Color and Shape:White PowderMolecular weight:374.37Oxaprozin
CAS:Formula:C18H15NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:293.32Anti-inflammatory agent 56
CAS:Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties byFormula:C21H15F3N4O4SPurity:98%Color and Shape:SolidMolecular weight:476.43Cimicoxib
CAS:Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.Formula:C16H13ClFN3O3SPurity:98.22%Color and Shape:SolidMolecular weight:381.81Ref: TM-T30937
1mg47.00€2mg58.00€5mg84.00€10mg111.00€25mg178.00€50mg269.00€100mg400.00€1mL*10mM (DMSO)92.00€Diflunisal
CAS:Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.Formula:C13H8F2O3Purity:98.92% - 99.42%Color and Shape:SolidMolecular weight:250.2
