Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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BMP-4
CAS:BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.Formula:C52H93N25O13SColor and Shape:SolidMolecular weight:1308.52Seratrodast
CAS:Seratrodast (ABT-001), a TXA2 receptor blocker, treats asthma; first approved in Japan, 1997.Formula:C22H26O4Purity:99.54% - 99.69%Color and Shape:Pale Orange SolidMolecular weight:354.44Ref: TM-T0212
10mg50.00€25mg72.00€50mg93.00€100mg139.00€200mg173.00€500mg283.00€1mL*10mM (DMSO)52.00€2-[2-(2,6-Dichlorophenyl)aminophenyl]ethanoic acid
CAS:Formula:C14H11Cl2NO2Purity:99%Color and Shape:SolidMolecular weight:296.1486Tetrahydroamentoflavone
CAS:Tetrahydroamentoflavone is a potent XO inhibitor (IC50 = 92 nM, Ki = 982 nM) with anti-inflammatory effects.Formula:C30H22O10Purity:98%Color and Shape:SolidMolecular weight:542.49Curcumin (Natural)
CAS:Formula:C21H20O6Color and Shape:Light yellow to Brown powder to crystalMolecular weight:368.39Etoricoxib-d4
CAS:Etoricoxib-d4 is the 2H-labeled form of Etoricoxib. Etoricoxib is a COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.Formula:C18H11D4ClN2O2SPurity:100%Color and Shape:SolidMolecular weight:362.87Betamethasone Valerate
CAS:Formula:C27H37FO6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:476.59Naproxen sodium
CAS:Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Formula:C14H13NaO3Purity:99.68% - 99.79%Color and Shape:White PowderMolecular weight:252.24COX-2-IN-2
CAS:COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.Formula:C17H12FN3O2SPurity:98.85%Color and Shape:SolidMolecular weight:341.36Ref: TM-T10032
1mg172.00€5mg416.00€10mg667.00€25mg1,330.00€50mg2,118.00€100mg2,812.00€1mL*10mM (DMSO)424.00€Teriflunomide impurity 3
CAS:Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).Formula:C14H11F3N2OPurity:99.62%Color and Shape:SolidMolecular weight:280.25Ref: TM-T9042
10mg50.00€25mg90.00€50mg134.00€100mg212.00€200mg303.00€500mgTo inquire1mL*10mM (DMSO)35.00€Rofecoxib
CAS:Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandinsFormula:C17H14O4SPurity:99.68% - 99.94%Color and Shape:Off-White (Pale Yellow) Crystalline PowderMolecular weight:314.36COX-2-IN-6
CAS:COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.Formula:C20H27NO6SPurity:98.62% - 99.56%Color and Shape:SoildMolecular weight:409.5CAY10404
CAS:CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34Ref: TM-T8656
2mg35.00€5mg52.00€10mg96.00€25mg177.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)58.00€Xanthohumol
CAS:Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-Formula:C21H22O5Purity:98.19% - 99.67%Color and Shape:Orange PowderMolecular weight:354.4Ref: TM-T3342
5mg66.00€10mg99.00€25mg205.00€50mg305.00€100mg459.00€500mg1,026.00€1mL*10mM (DMSO)74.00€Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.73%Color and Shape:White PowderMolecular weight:354.31Regaloside B
CAS:Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitricFormula:C20H26O11Purity:97.34% - 99.4%Color and Shape:SolidMolecular weight:442.41Metamizole sodium hydrate
CAS:Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).Formula:C13H18N3NaO5SPurity:99.69% - ≥98%Color and Shape:White Or Light Yellow Crystalline Powder Odorless Tiny BitterMolecular weight:351.36COX-2-IN-49
COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.Color and Shape:Odour SolidRofecoxib
CAS:Formula:C17H14O4SPurity:>98.0%(GC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:314.36
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