Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Rebamipide mofetil
CAS:Rebamipide mofetil is an orally active prodrug of Rebamipide which is a mucoprotective agent.Formula:C25H26ClN3O5Purity:99.78%Color and Shape:SolidMolecular weight:483.94Ref: TM-T9472
1mg66.00€2mg96.00€5mg144.00€10mg216.00€25mg406.00€50mg607.00€100mg845.00€1mL*10mM (DMSO)159.00€Ketorolac
CAS:Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.Formula:C15H13NO3Purity:99.68%Color and Shape:White Crystalline Or White PowderMolecular weight:255.27Tiaprofenic acid
CAS:Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.Formula:C14H12O3SPurity:99.51%Color and Shape:SolidMolecular weight:260.31Dehydrodiisoeugenol
CAS:Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.Formula:C20H22O4Purity:99.97%Color and Shape:SolidMolecular weight:326.39Progesic dihydrate
CAS:Fenoprofen calcium hydrate (Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).Formula:C30H30CaO8Purity:100%Color and Shape:SolidMolecular weight:558.63Methyl 2,5-Dihydroxycinnamate
CAS:Formula:C10H10O4Purity:>96.0%(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:194.19Etofenamate
CAS:Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.Formula:C18H18F3NO4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:369.33Glafenine
CAS:Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of variousFormula:C19H17ClN2O4Purity:98.49%Color and Shape:SolidMolecular weight:372.8Tenoxicam
CAS:Formula:C13H11N3O4S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:337.37Pamicogrel
CAS:Pamicogrel (KBT3022) is an inhibitor of COX.Formula:C25H24N2O4SPurity:99.83%Color and Shape:SolidMolecular weight:448.53Ref: TM-T15645
2mg35.00€5mg52.00€10mg78.00€25mg140.00€50mg216.00€100mg349.00€200mg515.00€1mL*10mM (DMSO)52.00€Rutaecarpine
CAS:Rutaecarpine (Rhetine) is an inhibitor of COX-2 with IC50 of 0.28 μM.Formula:C18H13N3OPurity:100% - 97.54%Color and Shape:White SolidMolecular weight:287.32Macelignan
CAS:Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.Formula:C20H24O4Purity:100% - 98.01%Color and Shape:SolidMolecular weight:328.4Ginsenoside C-K
CAS:Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.Formula:C36H62O8Purity:98.09% - 99.65%Color and Shape:SolidMolecular weight:622.87Robenacoxib
CAS:Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.Formula:C16H13F4NO2Purity:98.51%Color and Shape:SolidMolecular weight:327.27Ref: TM-T26109
1mg69.00€2mg89.00€5mg149.00€10mg235.00€25mg455.00€50mg723.00€100mg938.00€500mg1,882.00€Acetylsalicylic Acid
CAS:Formula:C9H8O4Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:180.16Parecoxib Sodium
CAS:Formula:C19H17N2NaO4SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:392.40COX-1/2-IN-9
COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.Formula:C30H20IN9O13S2Color and Shape:SolidMolecular weight:905.57Salicin
CAS:Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.Formula:C13H18O7Purity:98.2% - 99.86%Color and Shape:White Crystals Or PowderMolecular weight:286.28Loxoprofen sodium dihydrate
CAS:Formula:C15H21NaO5Purity:98%Color and Shape:SolidMolecular weight:304.314Celecoxib
CAS:Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor.Formula:C17H14F3N3O2SPurity:100% - 99.98%Color and Shape:White PowderMolecular weight:381.37
