Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Aceclofenac
CAS:Formula:C16H13Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:354.18471999999997Tinoridine hydrochloride
CAS:Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.Formula:C17H21ClN2O2SPurity:97.49%Color and Shape:SolidMolecular weight:352.88Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:96.17% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64Flurbiprofen
CAS:Formula:C15H13FO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:244.27Ibuprofen
CAS:Formula:C13H18O2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:206.29Diflunisal
CAS:Formula:C13H8F2O3Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalineMolecular weight:250.20Catechin
CAS:Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.Formula:C15H14O6Purity:97.34% - 99.82%Color and Shape:SolidMolecular weight:290.27Pelubiprofen
CAS:Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.312-(3-Benzoylphenyl)propionic acid
CAS:Formula:C16H14O3Purity:98%Color and Shape:SolidMolecular weight:254.2806COX/5-LO-IN-1
CAS:COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37Hamaudol
CAS:Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).Formula:C15H16O5Purity:99.62%Color and Shape:SolidMolecular weight:276.28Meloxicam
CAS:Formula:C14H13N3O4S2Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Green powder to crystalineMolecular weight:351.40(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formula:C25H25ClN2O4SPurity:98.80%Color and Shape:SolidMolecular weight:484.995-Amino-2-hydroxybenzoic acid
CAS:Formula:C7H7NO3Purity:98%Color and Shape:SolidMolecular weight:153.13538COX-2-IN-51
CAS:COX-2-IN-51 (E25) is a potent COX-2 inhibitor with an IC50 of 70.7 nM. It significantly suppresses LPS-induced release of NO and PGE2, the expression of COX-2 and iNOS, and the activation of the NF-κB pathway. Displaying anti-inflammatory and analgesic effects in various mouse models through NF-κB pathway inhibition, COX-2-IN-51 has lower gastrointestinal side effects compared to Indomethacin.Formula:C23H18F4O3SColor and Shape:SolidMolecular weight:450.446Sodium (2-amino-3-(4-bromobenzoyl)phenyl)acetate
CAS:Formula:C30H28Br2N2Na2O9Purity:99%Color and Shape:SolidMolecular weight:766.3389Jaceosidin
CAS:Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.Formula:C17H14O7Purity:98.23% - 99.28%Color and Shape:SolidMolecular weight:330.29Indobufen
CAS:Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor.Formula:C18H17NO3Purity:99.44% - 99.63%Color and Shape:SolidMolecular weight:295.33Anti-inflammatory agent 52
Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29Formula:C24H21ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:452.95
