GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Products of "GluR"
Sort by
ADX88178
CAS:ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.Formula:C12H12N6SPurity:99.55%Color and Shape:SolidMolecular weight:272.33Ref: TM-T4500
2mg38.00€5mg58.00€10mg96.00€25mg156.00€50mg243.00€100mg354.00€200mg505.00€1mL*10mM (DMSO)60.00€LY392098
CAS:LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.Formula:C18H22FNO2SPurity:99.85%Color and Shape:SolidMolecular weight:335.44Ref: TM-T27951
1mg42.00€5mg87.00€10mg140.00€25mg226.00€50mg324.00€100mg437.00€200mg605.00€1mL*10mM (DMSO)92.00€NS 1209
CAS:NS 1209 (SPD 502) is a AMPA receptor antagonist.Formula:C24H27N4NaO7SPurity:98%Color and Shape:SolidMolecular weight:538.55PHCCC
CAS:PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.Formula:C17H14N2O3Purity:99.31%Color and Shape:SolidMolecular weight:294.3(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Formula:C10H10ClNO6Purity:99.06% - 99.90%Color and Shape:SoildMolecular weight:275.64Ref: TM-T23288L
1mg183.00€5mg462.00€10mg660.00€25mg1,035.00€50mg1,415.00€100mg1,872.00€500mg3,763.00€1mL*10mM (DMSO)415.00€Dasolampanel
CAS:Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.Formula:C17H20ClN5O3Purity:99%Color and Shape:SolidMolecular weight:377.83VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Formula:C18H15FN2OPurity:99.65%Color and Shape:SolidMolecular weight:294.32Ref: TM-T29126
1mg57.00€5mg120.00€10mg187.00€25mg376.00€50mg588.00€100mg833.00€1mL*10mM (DMSO)115.00€XAP044
CAS:XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.Formula:C15H9IO4Purity:97.41%Color and Shape:SolidMolecular weight:380.13Ref: TM-T21995
1mg62.00€2mg87.00€5mg113.00€10mg207.00€25mg369.00€50mg557.00€100mg797.00€1mL*10mM (DMSO)155.00€DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Formula:C8H9NO4Purity:99.55%Color and Shape:SolidMolecular weight:183.16VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Formula:C13H11ClN2O2Purity:99.09% - 99.86%Color and Shape:SolidMolecular weight:262.69Philanthotoxin 74 dihydrochloride
CAS:Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.Formula:C24H44Cl2N4O3Purity:98.6%Color and Shape:SolidMolecular weight:507.54CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purity:99.70%Color and Shape:Pale Yellow SolidMolecular weight:232.15Ro 67-7476
CAS:Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.Formula:C17H18FNO2SPurity:99.48%Color and Shape:SolidMolecular weight:319.39Ref: TM-T3478
1mg35.00€2mg50.00€5mg93.00€10mg131.00€25mg258.00€50mg465.00€100mg680.00€1mL*10mM (DMSO)82.00€JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Formula:C23H25F3N4Color and Shape:SolidMolecular weight:414.47Ref: TM-T8862
1mg37.00€5mg80.00€10mg116.00€25mg259.00€50mg383.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)93.00€IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Formula:C16H16N2O2Purity:98.34%Color and Shape:SolidMolecular weight:268.31Ref: TM-T22736
1mg35.00€5mg70.00€10mg104.00€25mg202.00€50mg311.00€100mg472.00€500mg1,017.00€1mL*10mM (DMSO)85.00€JNJ-55511118
CAS:JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.Formula:C14H8ClF3N2O2Color and Shape:SolidMolecular weight:328.67Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Formula:C12H19ClN2O7S2Purity:99.01%Color and Shape:SolidMolecular weight:402.87Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Formula:C18H13ClFN3Purity:98.35%Color and Shape:SolidMolecular weight:325.77Ref: TM-T12717
1mg78.00€5mg169.00€10mg246.00€25mg406.00€50mg562.00€100mg702.00€200mg949.00€1mL*10mM (DMSO)178.00€3-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Formula:C8H9NO4SPurity:98.41% - 99.05%Color and Shape:SolidMolecular weight:215.23KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Formula:C22H12F3N5Na2O7Purity:96.85%Color and Shape:SoildMolecular weight:561.33Ref: TM-T27748L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€500mg3,734.00€LY3020371 hydrochloride
CAS:LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Formula:C15H16ClF2NO5SColor and Shape:SolidMolecular weight:395.81JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Formula:C20H17FN2O3Purity:99.24%Color and Shape:SolidMolecular weight:352.36A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Formula:C19H18N4OSPurity:≥98%Color and Shape:SolidMolecular weight:350.44GET73
CAS:GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Formula:C13H16F3NO2Purity:99.54%Color and Shape:SolidMolecular weight:275.27Ref: TM-T11393
1mg65.00€5mg131.00€10mg202.00€25mg340.00€50mg452.00€100mg638.00€200mg842.00€1mL*10mM (DMSO)177.00€γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Formula:C7H12N2O5Purity:98%Color and Shape:SolidMolecular weight:204.18VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Formula:C20H10Cl3N3O3Purity:97.03%Color and Shape:SolidMolecular weight:446.67Ref: TM-T21747
2mg42.00€5mg64.00€10mg97.00€25mg183.00€50mg284.00€100mg425.00€200mg562.00€1mL*10mM (DMSO)78.00€E4CPG
CAS:E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.Formula:C11H13NO4Purity:99.96%Color and Shape:SolidMolecular weight:223.23L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1LY-2300559
CAS:LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.Formula:C26H26O6Purity:100%Color and Shape:SolidMolecular weight:434.48Ref: TM-T27932
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purity:99% - 99.99%Color and Shape:SolidMolecular weight:305.32Fenobam
CAS:Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).Formula:C11H11ClN4O2Purity:99.93%Color and Shape:SolidMolecular weight:266.68Ref: TM-T15275
1mg35.00€5mg64.00€10mg101.00€25mg170.00€50mg248.00€100mg359.00€200mg497.00€1mL*10mM (DMSO)96.00€DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)Formula:C8H4N4O6Purity:97.15% - 99.10%Color and Shape:Off-White Powder With A Yellow TingeMolecular weight:252.14JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).Formula:C20H25ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:344.88Ref: TM-TQ0094
1mg55.00€5mg117.00€10mg183.00€25mg306.00€50mg437.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)131.00€S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFormula:C10H12N2O2SPurity:99.25%Color and Shape:SolidMolecular weight:224.281H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurity:99.69%Color and Shape:SoildMolecular weight:224.28VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Formula:C14H15Cl2NO3Purity:99.52% - 99.56%Color and Shape:SolidMolecular weight:316.18Ref: TM-T3565
2mg40.00€5mg58.00€10mg85.00€25mg145.00€50mg188.00€100mg301.00€200mg435.00€1mL*10mM (DMSO)64.00€(S)-ATPO
CAS:(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.Formula:C11H19N2O7PPurity:98.37% - 99.41%Color and Shape:SolidMolecular weight:322.25(RS)-3-Hydroxyphenylglycine
CAS:(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.Formula:C8H9NO3Purity:99.92%Color and Shape:SolidMolecular weight:167.16MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Formula:C4H10NO6PPurity:98%Color and Shape:SolidMolecular weight:199.1ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Formula:C21H20FNO3Purity:99.09%Color and Shape:SolidMolecular weight:353.39Ref: TM-T23003
1mg35.00€5mg64.00€10mg97.00€25mg207.00€50mg309.00€100mgTo inquire1mL*10mM (DMSO)75.00€(RS)-MCPG
CAS:(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:99.96%Color and Shape:SolidMolecular weight:209.2Ref: TM-T3479
1mg35.00€2mg48.00€5mg70.00€10mg87.00€25mg187.00€50mg338.00€100mg502.00€1mL*10mM (DMSO)74.00€Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Formula:C16H12FN3Purity:98.7%Color and Shape:SolidMolecular weight:265.29Ref: TM-T15134
1mg97.00€5mg227.00€10mg329.00€25mg723.00€50mg1,064.00€100mg1,415.00€1mL*10mM (DMSO)274.00€VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Formula:C21H15FN2O4Purity:96.68% - 98.44%Color and Shape:SolidMolecular weight:378.35Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Formula:C14H16Cl2N2O2Purity:97.96%Color and Shape:SolidMolecular weight:315.2AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Formula:C28H30Cl2N2Purity:97.23% - 98.34%Color and Shape:SolidMolecular weight:465.46NBQX Disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurity:98.22%Color and Shape:SolidMolecular weight:380.24NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Formula:C12H8N4O6SPurity:97.66% - 99.42%Color and Shape:SolidMolecular weight:336.28Ref: TM-T4113
1mg40.00€5mg89.00€10mg127.00€25mg246.00€50mg369.00€100mg525.00€200mg757.00€1mL*10mM (DMSO)87.00€
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
