BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
Products of "BACE"
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Anti-BACE1 Antibody (8D358)
Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.Color and Shape:Odour LiquidAtabecestat
CAS:Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Formula:C18H14FN5OSPurity:98.49% - 99.77%Color and Shape:SolidMolecular weight:367.4Ref: TM-T14338
1mg130.00€5mg311.00€10mg502.00€25mg1,008.00€50mg1,349.00€100mg1,825.00€1mL*10mM (DMSO)344.00€Umibecestat
CAS:Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.Formula:C19H15ClF7N5O2Purity:100%Color and Shape:SolidMolecular weight:513.8Ref: TM-T13253
1mg172.00€5mg354.00€10mg512.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)418.00€Anti-BACE1 Antibody (3R945)
Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.Color and Shape:Odour LiquidLY2811376
CAS:LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).Formula:C15H14F2N4SPurity:99% - 99.01%Color and Shape:SolidMolecular weight:320.36Ref: TM-T2639
1mg52.00€2mg73.00€5mg123.00€10mg205.00€25mg374.00€50mg560.00€100mg800.00€1mL*10mM (DMSO)123.00€LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurity:99.45%Color and Shape:SolidMolecular weight:474.91Ref: TM-T4398
2mg37.00€5mg52.00€10mg84.00€25mg137.00€50mg229.00€100mg340.00€200mg472.00€1mL*10mM (DMSO)58.00€Questin
CAS:Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V.Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26Verubecestat
CAS:Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.Formula:C17H17F2N5O3SPurity:99.49% - ≥98%Color and Shape:SolidMolecular weight:409.41Ref: TM-T7011
2mg40.00€5mg60.00€10mg88.00€25mg153.00€50mg216.00€100mg354.00€500mg825.00€1mL*10mM (DMSO)66.00€AZD3839 free base
CAS:AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.Formula:C24H16F3N5Purity:99.93% - 99.96%Color and Shape:SolidMolecular weight:431.41Tenuifolin
CAS:Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.Formula:C36H56O12Purity:97.37% - 99.9%Color and Shape:SolidMolecular weight:680.82SEW06622
CAS:SEW06622 is a inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.Formula:C21H26N2O2Purity:99.87%Color and Shape:SoildMolecular weight:338.44Elenbecestat
CAS:Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.Formula:C19H18F3N5O2SPurity:99.95%Color and Shape:SolidMolecular weight:437.44Ref: TM-T11175
1mg70.00€5mg153.00€10mg250.00€25mg520.00€50mg750.00€100mg1,026.00€1mL*10mM (DMSO)166.00€Anti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.Color and Shape:Odour LiquidLY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Formula:C18H16F2N4O2SPurity:99% - 99.94%Color and Shape:SolidMolecular weight:390.41BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:75 kDa (predicted); 100-105 kDa (reducing condition, due to glycosylation)BACE1-IN-2
CAS:BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).Formula:C19H15F4N5O2Purity:98%Color and Shape:SolidMolecular weight:421.35Anti-BACE1 Antibody (2Z488)
Anti-BACE1 Antibody (2Z488) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (2Z488) can be used in ELISA.Color and Shape:Odour LiquidPF-06751979
CAS:PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).Formula:C18H19F2N5O3S2Purity:98%Color and Shape:SolidMolecular weight:455.5Anti-BACE1 Antibody-FITC (8D358)
Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.Color and Shape:Odour LiquidUmibecestat HCl
CAS:Umibecestat HCl (CNP520 HCl) is an efficient β-secretase (BACE1/BACE2) inhibitor that reduces Aβ levels in mice and rats.Formula:C19H16Cl2F7N5O2Purity:99.92%Color and Shape:SolidMolecular weight:550.26
