AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Terodiline hydrochloride
CAS:Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),Formula:C20H28ClNPurity:98%Color and Shape:SolidMolecular weight:317.9Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Formula:C11H15ClN4O2Purity:98.42%Color and Shape:Light-Yellow CrystalMolecular weight:270.72nAChR agonist 1
CAS:nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.Formula:C20H18ClNO3S2Purity:97.59%Color and Shape:SolidMolecular weight:419.94Ref: TM-T12165
1mg94.00€5mg170.00€10mg259.00€25mg424.00€50mg562.00€100mg775.00€200mg1,026.00€1mL*10mM (DMSO)192.00€Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Formula:C35H60Br2N2O4Purity:99.86%Color and Shape:solidMolecular weight:732.67Ref: TM-T0166
5mg38.00€10mg55.00€25mg82.00€50mg115.00€100mg188.00€200mg235.00€500mg394.00€1mL*10mM (DMSO)63.00€Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formula:C28H31BrN2O2Purity:100% - 99.75%Color and Shape:SolidMolecular weight:505.45VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.Formula:C18H20N6O3S2Purity:96.53% - 98.26%Color and Shape:SolidMolecular weight:432.52Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Formula:C20H25NO2·HClPurity:97.76% - 99.13%Color and Shape:White Or Almost White PowderMolecular weight:347.88Methacholine Chloride
CAS:Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine.Formula:C8H18ClNO2Purity:99.37% - 99.74%Color and Shape:White Hygroscopic Crystals With Slight Odor Of Dead FishMolecular weight:195.69Ispronicline
CAS:Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitiveFormula:C14H22N2OPurity:96.49% - 99.16%Color and Shape:SolidMolecular weight:234.348-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:98.34%Color and Shape:SolidMolecular weight:150.14PNU-120596
CAS:PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.Formula:C13H14ClN3O4Purity:98.34%Color and Shape:SolidMolecular weight:311.72suvn-911
CAS:suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.Formula:C11H14Cl2N2OPurity:98.88%Color and Shape:SolidMolecular weight:261.15Ref: TM-T9787
1mg71.00€5mg140.00€10mg215.00€25mg359.00€50mg510.00€100mg695.00€200mg937.00€1mL*10mM (DMSO)182.00€MHP 133
CAS:MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).Formula:C17H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:377.83Ipratropium Bromide
CAS:Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.Formula:C20H30BrNO3Purity:99.91%Color and Shape:SolidMolecular weight:412.37Varenicline Tartrate
CAS:Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.Formula:C13H13N3·C4H6O6Purity:98.23% - 98.32%Color and Shape:Tan SolidMolecular weight:361.35GSK233705
CAS:GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.Formula:C24H29BrN2Purity:99.67% - 99.76%Color and Shape:SolidMolecular weight:425.4DMAB-anabaseine dihydrochloride
CAS:DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containingFormula:C19H23Cl2N3Purity:99.86%Color and Shape:SolidMolecular weight:364.31A-867744
CAS:A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.Formula:C25H25N3O2Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:399.48JHU37152
CAS:JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.Formula:C19H20ClFN4Purity:99.72%Color and Shape:SolidMolecular weight:358.84Ref: TM-T9019
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg255.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)58.00€Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Formula:C11H19IN2OPurity:98.75%Color and Shape:SolidMolecular weight:322.19LY2119620
CAS:LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.Formula:C19H24ClN5O3SPurity:99.7%Color and Shape:SolidMolecular weight:437.94UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69NBTGR
CAS:NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).Formula:C17H18N6O6SPurity:98%Color and Shape:SolidMolecular weight:434.43mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purity:98%Color and Shape:SolidMolecular weight:488.36VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Formula:C17H15F3N4O3S2Purity:98.05% - 98.28%Color and Shape:SolidMolecular weight:444.45Ref: TM-T17244
1mg52.00€5mg97.00€10mg139.00€25mg263.00€50mg444.00€100mg772.00€200mg1,026.00€1mL*10mM (DMSO)111.00€CHF5407
CAS:CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFormula:C27H25BrF4N2O3SPurity:100%Color and Shape:SolidMolecular weight:613.46V-11-0711 HCl
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.Formula:C27H36ClNO3Purity:100%Color and Shape:SolidMolecular weight:458.03Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Ref: TM-T4246L
2mg35.00€5mg52.00€10mg80.00€25mg144.00€50mg210.00€100mg329.00€200mg490.00€1mL*10mM (DMSO)58.00€CCMI
CAS:CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.Formula:C19H15Cl2N3O2Purity:100%Color and Shape:SolidMolecular weight:388.25M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurity:98.25%Color and Shape:SolidMolecular weight:290.38SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFormula:C13H20ClNOSPurity:99.47% - 99.71%Color and Shape:SolidMolecular weight:273.82Tacrine hydrochloride (hydrate)
CAS:Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.Formula:C13H14N2·XHCl·XH2OPurity:99.01% - 99.89%Color and Shape:SolidMolecular weight:234.72PNU-282987
CAS:PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).Formula:C14H18Cl2N2OPurity:100% - 99.92%Color and Shape:SolidMolecular weight:301.21PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Formula:C28H32N2O3Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:444.57Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Formula:C16H25N3O5SPurity:98.22%Color and Shape:SolidMolecular weight:371.45Ref: TM-T13353
5mg38.00€10mg58.00€25mg105.00€50mg168.00€100mg259.00€200mg373.00€1mL*10mM (DMSO)42.00€SEN12333
CAS:SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonistFormula:C20H25N3O2Purity:99.02%Color and Shape:SolidMolecular weight:339.43Ref: TM-T23348
2mg39.00€5mg57.00€10mg95.00€25mg167.00€50mg269.00€100mg432.00€200mg622.00€1mL*10mM (DMSO)63.00€AChE/BChE-IN-10
CAS:AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.Formula:C26H30N2O2Purity:99.55% - 99.75%Color and Shape:SoildMolecular weight:402.53Ref: TM-T61969
5mg44.00€10mg67.00€25mg126.00€50mg188.00€100mg306.00€200mg454.00€1mL*10mM (DMSO)54.00€N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31Trospium chloride
CAS:Trospium chloride treats urinary incontinence without causing liver damage.Formula:C25H30ClNO3Purity:100% - 99.92%Color and Shape:White To Off-White PowderMolecular weight:427.964bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.Formula:C24H38Br2N2Purity:98.72%Color and Shape:SolidMolecular weight:514.38Ref: TM-T37818
2mg43.00€5mg60.00€10mg96.00€25mg188.00€50mg278.00€100mg411.00€200mg607.00€1mL*10mM (DMSO)73.00€Ursulcholic acid
CAS:Ursulcholic acid (Ursulcholic) is a water-soluble anticholinergic compound.Formula:C24H40O10S2Purity:98%Color and Shape:SolidMolecular weight:552.7Loxeen
CAS:Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.Formula:C20H25NO·CH4O3SPurity:99.46%Color and Shape:White To Off-White Crystalline PowderMolecular weight:391.52Otenzepad
CAS:Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Formula:C24H31N5O2Purity:99.81%Color and Shape:SolidMolecular weight:421.54Cimetropium Bromide
CAS:Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.Formula:C21H28BrNO4Color and Shape:SolidMolecular weight:438.36Nitrobenzylthioinosine
CAS:Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.Formula:C17H17N5O6SPurity:98.83% - 99.69%Color and Shape:Off-White SolidMolecular weight:419.414-DAMP
CAS:4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formula:C21H26INO2Purity:98%Color and Shape:SolidMolecular weight:451.34Imidafenacin
CAS:Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.Formula:C20H21N3OPurity:99.17%Color and Shape:SolidMolecular weight:319.4Tolterodine
CAS:Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.Formula:C22H31NOPurity:99.71%Color and Shape:White Like Or Light Brown Crystalline PowderMolecular weight:325.49Mepenzolate Bromide
CAS:Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.Formula:C21H26BrNO3Purity:95.73% - 99.21%Color and Shape:SolidMolecular weight:420.34Aclidinium bromide
CAS:Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.Formula:C26H30NO4S2·BrPurity:98.93% - 99.69%Color and Shape:SolidMolecular weight:564.55Ref: TM-T2555
2mg39.00€5mg57.00€10mg88.00€25mg145.00€50mg234.00€100mg350.00€500mg825.00€1mL*10mM (DMSO)72.00€Clidinium bromide
CAS:Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.Formula:C22H26BrNO3Purity:98.89% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:432.35SQ22536
CAS:SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.Formula:C9H11N5OPurity:99.18%Color and Shape:Off-White SolidMolecular weight:205.22SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Formula:C14H16N2O4Purity:98.25% - 99%Color and Shape:SolidMolecular weight:276.29Ref: TM-T34573
1mg118.00€5mg275.00€10mg419.00€25mg692.00€50mg938.00€100mg1,320.00€500mg2,632.00€1mL*10mM (DMSO)263.00€Benzetimide hydrochloride
CAS:Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.Formula:C23H27ClN2O2Purity:99.32%Color and Shape:Off-White PowderMolecular weight:398.93Oxitropium Bromide
CAS:Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.Formula:C19H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:412.32Nanofin
CAS:Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.Formula:C7H15NPurity:99.818%Color and Shape:Clear Colorless To Slightly Yellow LiquidMolecular weight:113.2AF-DX 384 free base
CAS:AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.Formula:C27H38N6O2Purity:98%Color and Shape:SolidMolecular weight:478.63TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).Formula:C24H24FN3O3Purity:98.02%Color and Shape:SolidMolecular weight:421.46Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Formula:C6H15ClN2O2Purity:100% - 90%Color and Shape:SolidMolecular weight:182.65Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purity:99.87%Color and Shape:SolidMolecular weight:362.46Vecuronium bromide
CAS:Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscleFormula:C34H57BrN2O4Purity:99.63% - 99.92%Color and Shape:White PowderMolecular weight:637.73VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).Formula:C18H15FN4OPurity:99.48%Color and Shape:SolidMolecular weight:322.34Lupinine
CAS:Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.Formula:C10H19NOPurity:99.95%Color and Shape:SolidMolecular weight:169.26Ref: TM-FR16605
1mg95.00€5mg180.00€10mg271.00€25mg462.00€50mg672.00€100mg918.00€500mg1,840.00€1ml*10 (DMSO)151.00€Pempidine
CAS:Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.Formula:C10H21NPurity:98.18% - 99.92%Color and Shape:Colorless - Light Yellow Clear LiquidMolecular weight:155.28Atropine methyl bromide
CAS:Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist.Formula:C18H26BrNO3Purity:99.70%Color and Shape:SolidMolecular weight:384.308Ref: TM-T14345
1mg35.00€5mg70.00€10mg105.00€25mg187.00€50mg274.00€100mg404.00€200mg587.00€1mL*10mM (DMSO)77.00€Nor-benzetimide
CAS:Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.Formula:C16H20N2O2Purity:98.63%Color and Shape:SolidMolecular weight:272.34Ref: TM-T22380
1mg93.00€2mg126.00€5mg187.00€10mg283.00€25mg462.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)187.00€Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purity:99.78%Color and Shape:SolidMolecular weight:531.6Ref: TM-T13385
1mg40.00€5mg88.00€10mg119.00€25mg216.00€50mg354.00€100mg533.00€200mg743.00€1mL*10mM (DMSO)93.00€RPR121056
CAS:RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.Formula:C33H38N4O8Purity:98%Color and Shape:SolidMolecular weight:618.68GSK-1034702
CAS:GSK-1034702 is an M1 mAChR agonist that improves cognitive deficits and may be useful in the study of neurologic disorders.Formula:C18H24FN3O2Purity:99.69%Color and Shape:SolidMolecular weight:333.4Sch412348
CAS:Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.Formula:C22H21F2N9OPurity:98%Color and Shape:SolidMolecular weight:465.46Tebanicline hydrochloride
CAS:Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.Formula:C9H12Cl2N2OPurity:95% - 98.71%Color and Shape:SolidMolecular weight:235.11(Rac)-Sabcomeline
CAS:(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.Formula:C10H15N3OPurity:99.14%Color and Shape:SolidMolecular weight:193.25Carbetapentane citrate
CAS:Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.Formula:C20H31NO3·C6H8O7Purity:99.46%Color and Shape:White To Off-White SolidMolecular weight:525.59VU0152099
CAS:VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).Formula:C18H17N3O3SPurity:98.46%Color and Shape:SolidMolecular weight:355.41GTS-21
CAS:GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.Formula:C19H20N2O2Purity:98%Color and Shape:SolidMolecular weight:308.37TBPB
CAS:TBPB is an allosteric M1 mAChR agonist.Formula:C25H32N4OPurity:97.87% - 99.9%Color and Shape:SolidMolecular weight:404.55NKH477
CAS:NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.Formula:C27H44ClNO8Purity:98% - 98%Color and Shape:SolidMolecular weight:546.09TZ3O
CAS:TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Formula:C18H13NO4SPurity:99.84%Color and Shape:SolidMolecular weight:339.37Piperidolate hydrochloride
CAS:Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.Formula:C21H26ClNO2Purity:99.50%Color and Shape:SolidMolecular weight:359.89Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.84%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg127.00€5mg305.00€10mg550.00€25mg882.00€50mg1,206.00€100mg1,605.00€1mL*10mM (DMSO)338.00€Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Formula:C19H23N3O3Purity:99.96%Color and Shape:SolidMolecular weight:341.4A 582941 HCl (848591-90-2(free base))
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesFormula:C17H21ClN4Purity:99.83%Color and Shape:SolidMolecular weight:316.83Ref: TM-T8725
1mg88.00€5mg172.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)170.00€Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Formula:C18H23NO·C6H8O7Purity:98% - 99.51%Color and Shape:White SolidMolecular weight:461.54BP-TQS
CAS:4BP-TQS is an allosteric agonist of α7 nAChRs.Formula:C18H17BrN2O2SPurity:99.96%Color and Shape:SolidMolecular weight:405.31α-Muricholic acid
CAS:α-Muricholic acid is the most abundant primary bile acid in rodents.Formula:C24H40O5Purity:98%Color and Shape:SolidMolecular weight:408.57Succinylcholine Chloride Dihydrate
CAS:Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.Formula:C14H30N2O4·2Cl·2H2OPurity:99.87%Color and Shape:White SolidMolecular weight:397.34Propantheline bromide
CAS:Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscleFormula:C23H30BrNO3Purity:95% - ≥98%Molecular weight:448.4ML380
CAS:ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Ref: TM-T28069
2mg49.00€5mg74.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)82.00€(-)-(S)-B-973B
CAS:(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.Formula:C24H26F2N6OPurity:99.52%Color and Shape:SolidMolecular weight:452.5GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.Formula:C20H38Cl2N2O3S2Purity:98%Color and Shape:SolidMolecular weight:489.55Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Formula:C12H17ClN2OPurity:99.23%Color and Shape:SolidMolecular weight:240.729Ref: TM-T12201
5mg48.00€10mg71.00€25mg108.00€50mg160.00€100mg226.00€200mg331.00€1mL*10mM (DMSO)50.00€VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Formula:C22H14F3NO3Purity:97.29%Color and Shape:SolidMolecular weight:397.35Ref: TM-T13325
2mg38.00€5mg58.00€10mg82.00€25mg137.00€50mg224.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)65.00€Tazomeline
CAS:Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.Formula:C14H23N3S2Purity:100%Color and Shape:SolidMolecular weight:297.48Oxyphencyclimine Hydrochloride
CAS:Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.Formula:C20H29ClN2O3Purity:99.55%Color and Shape:SolidMolecular weight:380.91SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurity:99.64%Color and Shape:SoildMolecular weight:237.36Ref: TM-T16881L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€1mL*10mM (DMSO)47.00€Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Formula:C20H24N·CH3O4SPurity:98% - 99.27%Color and Shape:SolidMolecular weight:389.51Iperoxo
CAS:Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.Formula:C10H17IN2O2Purity:98.93%Color and Shape:SolidMolecular weight:324.16Ref: TM-T25538
1mg50.00€5mg107.00€10mg187.00€25mg411.00€50mg613.00€100mg873.00€500mg1,768.00€1mL*10mM (DMSO)117.00€Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49Ref: TM-T203814
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€
