AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
Sort by
Aclidinium bromide
CAS:Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.Formula:C26H30NO4S2·BrPurity:98.93% - 99.69%Color and Shape:SolidMolecular weight:564.55Ref: TM-T2555
2mg39.00€5mg57.00€10mg88.00€25mg145.00€50mg234.00€100mg350.00€500mg825.00€1mL*10mM (DMSO)72.00€Clidinium bromide
CAS:Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.Formula:C22H26BrNO3Purity:98.89% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:432.35SQ22536
CAS:SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.Formula:C9H11N5OPurity:99.18%Color and Shape:Off-White SolidMolecular weight:205.22SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Formula:C14H16N2O4Purity:98.25% - 99%Color and Shape:SolidMolecular weight:276.29Ref: TM-T34573
1mg118.00€5mg275.00€10mg419.00€25mg692.00€50mg938.00€100mg1,320.00€500mg2,632.00€1mL*10mM (DMSO)263.00€Benzetimide hydrochloride
CAS:Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.Formula:C23H27ClN2O2Purity:99.32%Color and Shape:Off-White PowderMolecular weight:398.93Oxitropium Bromide
CAS:Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.Formula:C19H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:412.32Nanofin
CAS:Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.Formula:C7H15NPurity:99.818%Color and Shape:Clear Colorless To Slightly Yellow LiquidMolecular weight:113.2AF-DX 384 free base
CAS:AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.Formula:C27H38N6O2Purity:98%Color and Shape:SolidMolecular weight:478.63TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).Formula:C24H24FN3O3Purity:98.02%Color and Shape:SolidMolecular weight:421.46Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Formula:C6H15ClN2O2Purity:100% - 90%Color and Shape:SolidMolecular weight:182.65Solifenacin
CAS:Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,Formula:C23H26N2O2Purity:99.87%Color and Shape:SolidMolecular weight:362.46Vecuronium bromide
CAS:Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscleFormula:C34H57BrN2O4Purity:99.63% - 99.92%Color and Shape:White PowderMolecular weight:637.73VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).Formula:C18H15FN4OPurity:99.48%Color and Shape:SolidMolecular weight:322.34Lupinine
CAS:Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.Formula:C10H19NOPurity:99.95%Color and Shape:SolidMolecular weight:169.26Ref: TM-FR16605
1mg95.00€5mg180.00€10mg271.00€25mg462.00€50mg672.00€100mg918.00€500mg1,840.00€1ml*10 (DMSO)151.00€Pempidine
CAS:Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.Formula:C10H21NPurity:98.18% - 99.92%Color and Shape:Colorless - Light Yellow Clear LiquidMolecular weight:155.28Atropine methyl bromide
CAS:Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist.Formula:C18H26BrNO3Purity:99.70%Color and Shape:SolidMolecular weight:384.308Ref: TM-T14345
1mg35.00€5mg70.00€10mg105.00€25mg187.00€50mg274.00€100mg404.00€200mg587.00€1mL*10mM (DMSO)77.00€Nor-benzetimide
CAS:Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.Formula:C16H20N2O2Purity:98.63%Color and Shape:SolidMolecular weight:272.34Ref: TM-T22380
1mg93.00€2mg126.00€5mg187.00€10mg283.00€25mg462.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)187.00€Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purity:99.78%Color and Shape:SolidMolecular weight:531.6Ref: TM-T13385
1mg40.00€5mg88.00€10mg119.00€25mg216.00€50mg354.00€100mg533.00€200mg743.00€1mL*10mM (DMSO)93.00€RPR121056
CAS:RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.Formula:C33H38N4O8Purity:98%Color and Shape:SolidMolecular weight:618.68GSK-1034702
CAS:GSK-1034702 is an M1 mAChR agonist that improves cognitive deficits and may be useful in the study of neurologic disorders.Formula:C18H24FN3O2Purity:99.69%Color and Shape:SolidMolecular weight:333.4Sch412348
CAS:Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.Formula:C22H21F2N9OPurity:98%Color and Shape:SolidMolecular weight:465.46Tebanicline hydrochloride
CAS:Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.Formula:C9H12Cl2N2OPurity:95% - 98.71%Color and Shape:SolidMolecular weight:235.11(Rac)-Sabcomeline
CAS:(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.Formula:C10H15N3OPurity:99.14%Color and Shape:SolidMolecular weight:193.25Carbetapentane citrate
CAS:Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.Formula:C20H31NO3·C6H8O7Purity:99.46%Color and Shape:White To Off-White SolidMolecular weight:525.59VU0152099
CAS:VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).Formula:C18H17N3O3SPurity:98.46%Color and Shape:SolidMolecular weight:355.41GTS-21
CAS:GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.Formula:C19H20N2O2Purity:98%Color and Shape:SolidMolecular weight:308.37TBPB
CAS:TBPB is an allosteric M1 mAChR agonist.Formula:C25H32N4OPurity:97.87% - 99.9%Color and Shape:SolidMolecular weight:404.55NKH477
CAS:NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.Formula:C27H44ClNO8Purity:98% - 98%Color and Shape:SolidMolecular weight:546.09TZ3O
CAS:TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Formula:C18H13NO4SPurity:99.84%Color and Shape:SolidMolecular weight:339.37Piperidolate hydrochloride
CAS:Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.Formula:C21H26ClNO2Purity:99.50%Color and Shape:SolidMolecular weight:359.89Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.84%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg127.00€5mg305.00€10mg550.00€25mg882.00€50mg1,206.00€100mg1,605.00€1mL*10mM (DMSO)338.00€Coluracetam
CAS:Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.Formula:C19H23N3O3Purity:99.96%Color and Shape:SolidMolecular weight:341.4A 582941 HCl (848591-90-2(free base))
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesFormula:C17H21ClN4Purity:99.83%Color and Shape:SolidMolecular weight:316.83Ref: TM-T8725
1mg88.00€5mg172.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)170.00€Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Formula:C18H23NO·C6H8O7Purity:98% - 99.51%Color and Shape:White SolidMolecular weight:461.54BP-TQS
CAS:4BP-TQS is an allosteric agonist of α7 nAChRs.Formula:C18H17BrN2O2SPurity:99.96%Color and Shape:SolidMolecular weight:405.31α-Muricholic acid
CAS:α-Muricholic acid is the most abundant primary bile acid in rodents.Formula:C24H40O5Purity:98%Color and Shape:SolidMolecular weight:408.57Succinylcholine Chloride Dihydrate
CAS:Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.Formula:C14H30N2O4·2Cl·2H2OPurity:99.87%Color and Shape:White SolidMolecular weight:397.34Propantheline bromide
CAS:Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscleFormula:C23H30BrNO3Purity:95% - ≥98%Molecular weight:448.4ML380
CAS:ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Ref: TM-T28069
2mg49.00€5mg74.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)82.00€(-)-(S)-B-973B
CAS:(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.Formula:C24H26F2N6OPurity:99.52%Color and Shape:SolidMolecular weight:452.5GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.Formula:C20H38Cl2N2O3S2Purity:98%Color and Shape:SolidMolecular weight:489.55Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Formula:C12H17ClN2OPurity:99.23%Color and Shape:SolidMolecular weight:240.729Ref: TM-T12201
5mg48.00€10mg71.00€25mg108.00€50mg160.00€100mg226.00€200mg331.00€1mL*10mM (DMSO)50.00€VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Formula:C22H14F3NO3Purity:97.29%Color and Shape:SolidMolecular weight:397.35Ref: TM-T13325
2mg38.00€5mg58.00€10mg82.00€25mg137.00€50mg224.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)65.00€Tazomeline
CAS:Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.Formula:C14H23N3S2Purity:100%Color and Shape:SolidMolecular weight:297.48Oxyphencyclimine Hydrochloride
CAS:Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.Formula:C20H29ClN2O3Purity:99.55%Color and Shape:SolidMolecular weight:380.91SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurity:99.64%Color and Shape:SoildMolecular weight:237.36Ref: TM-T16881L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€1mL*10mM (DMSO)47.00€Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Formula:C20H24N·CH3O4SPurity:98% - 99.27%Color and Shape:SolidMolecular weight:389.51Iperoxo
CAS:Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.Formula:C10H17IN2O2Purity:98.93%Color and Shape:SolidMolecular weight:324.16Ref: TM-T25538
1mg50.00€5mg107.00€10mg187.00€25mg411.00€50mg613.00€100mg873.00€500mg1,768.00€1mL*10mM (DMSO)117.00€Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49Ref: TM-T203814
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€
