
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
Show 4 more subcategories
Products of "Proteases/Proteasome"
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MMP-12 Inhibitor
CAS:MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.Formula:C19H20N2O7SPurity:97.51% - 99.63%Color and Shape:SoildMolecular weight:420.44Bortezomib-pinanediol
CAS:Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.Formula:C29H39BN4O4Purity:97.5%Color and Shape:Yellow SolidMolecular weight:518.462-Hydroxy-4-methoxybenzaldehyde
CAS:2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is an isomer of Vanillin, and a potent tyrosinase inhibitor, could be used to synthesis Urolithin M7.Formula:C8H8O3Purity:99.78%Color and Shape:Colorless Needle-Like CrystalMolecular weight:152.15Amylmetacresol
CAS:Amylmetacresol treats sore throat, pharyngitis, tonsillitis, laryngitis, influenza A, and SARS-CoV.Formula:C12H18OPurity:99.66%Color and Shape:SolidMolecular weight:178.27Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purity:98%Color and Shape:SolidMolecular weight:1322MMP Inhibitor 4
MMP Inhibitor4 (compound 4 B) is an effective MMP inhibitor with anti-proliferative properties. It induces cell cycle arrest at the subG1 phase and reduces the mRNA expression of MMP2, MMP9, and VEGFA.Formula:C16H18BrClN2O5Color and Shape:SolidMolecular weight:433.68Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Purity:98%Color and Shape:Odour SolidSimeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Formula:C38H47N5O7S2Purity:99.45% - 99.61%Color and Shape:SolidMolecular weight:749.94Ozagrel
CAS:Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement ofFormula:C13H12N2O2Purity:97.90% - 99.38%Color and Shape:White PowderMolecular weight:228.25TNO211
CAS:TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)-specifically MMP-2, 8, 12, 13Formula:C63H88N16O14SPurity:98%Color and Shape:SolidMolecular weight:1325.54Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Color and Shape:Odour SolidNSC 405020
CAS:NSC 405020 is a noncatalytic inhibitor of MT1-MMP.Formula:C12H15Cl2NOPurity:96.93% - 97%Color and Shape:SolidMolecular weight:260.16LV-320
CAS:LV-320, potent ATG4B inhibitor; IC50: 24.5 μM, Kd: 16 μM. Blocks autophagy, stable, non-toxic, active in vivo. Useful for ATG4B research in cancer.Formula:C29H26ClNO2S2Purity:98%Color and Shape:SolidMolecular weight:520.11Z-IETD-FMK
CAS:Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Formula:C30H43FN4O11Purity:95% - 99.81%Color and Shape:SolidMolecular weight:654.68Ref: TM-T7019
1mg125.00€2mg182.00€5mg263.00€10mg420.00€25mg682.00€50mgTo inquire1mL*10mM (DMSO)408.00€Emtricitabine
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity.Cost-effective and quality-assured.Formula:C8H10FN3O3SPurity:100% - 99.78%Color and Shape:White PowderMolecular weight:247.25PNU-103017
CAS:PNU-103017 is an inhibitor of HIV protease.Formula:C28H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:504.6Coblopasvir dihydrochloride
CAS:Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.Formula:C41H52Cl2N8O8Purity:99.33%Color and Shape:SolidMolecular weight:855.81Ref: TM-T25268L
1mg87.00€5mg187.00€10mg305.00€25mg518.00€50mg742.00€100mg1,017.00€1mL*10mM (DMSO)298.00€Clathrin-IN-1
CAS:Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.Formula:C20H13BrN2O3S2Purity:99.91%Color and Shape:SolidMolecular weight:473.36Ref: TM-T9063
1mg52.00€2mg77.00€5mg96.00€10mg149.00€25mg259.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)111.00€Licoricidin
CAS:Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.Formula:C26H32O5Purity:98%Color and Shape:SolidMolecular weight:424.53(ETHYLENEDINITRILO)TETRAACETIC ACID, TRISODIUM SALT HYDRATE
CAS:Formula:C10H18N2NaO9Purity:98%Color and Shape:SolidMolecular weight:333.24769000000003Tanomastat
CAS:Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.Formula:C23H19ClO3SPurity:98%Color and Shape:SolidMolecular weight:410.91Chondroitin sulfate
CAS:Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry conditionFormula:(C14H21NO14S)nPurity:99.87%Color and Shape:SolidMolecular weight:30,000-50,000MIV-247
CAS:MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.Formula:C17H24F3N3O4Purity:99.31%Color and Shape:SolidMolecular weight:391.39FMK 9a
CAS:FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formula:C23H21FN2O3Purity:98.97%Color and Shape:SolidMolecular weight:392.42Ref: TM-T15303
1mg139.00€5mg329.00€10mg494.00€25mg800.00€50mg1,103.00€100mg1,491.00€500mg2,973.00€1mL*10mM (DMSO)284.00€2-Fluoropalmitic acid
CAS:2-Fluoropalmitic acid, glioblastoma (GBM) by inhibiting the viability, proliferation, suppressing the expression of phosphorylated erk, CD133, and SOX-2, MMP-2.Formula:C16H31FO2Color and Shape:SolidMolecular weight:274.41Ac-VDQQD-pNA
CAS:Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).Formula:C31H43N9O14Color and Shape:SolidMolecular weight:765.734'-Hydroxychalcone
CAS:4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activityFormula:C15H12O2Purity:99.71% - 99.86%Color and Shape:Yellow-Cream PowderMolecular weight:224.25Lucidenic acid C
CAS:Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.Formula:C27H40O7Purity:98%Color and Shape:SolidMolecular weight:476.61,10-Phenanthroline hydrate
CAS:Formula:C12H10N2OPurity:98%Color and Shape:SolidMolecular weight:198.2206Ibalizumab
CAS:Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4Purity:SDS-PAGE:96.4%;SEC-HPLC:97.7%Color and Shape:LiquidMolecular weight:147.3 kDa(2R,3S)-Emricasan
CAS:(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.Formula:C26H27F4N3O7Color and Shape:SolidMolecular weight:569.5Delavirdine mesylate
CAS:Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).Formula:C23H32N6O6S2Purity:99.99%Color and Shape:Light Brown SolidMolecular weight:552.67Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26Daclatasvir dihydrochloride
CAS:Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8Ref: TM-T1786
1g244.00€5mg42.00€10mg50.00€25mg60.00€50mg71.00€100mg81.00€500mg170.00€1mL*10mM (DMSO)52.00€Rilpivirine
CAS:Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatmentFormula:C22H18N6Purity:97.22% - 98.83%Color and Shape:SolidMolecular weight:366.42Ref: TM-T2330
2mg38.00€5mg55.00€10mg88.00€25mg145.00€50mg243.00€100mg359.00€500mg842.00€1mL*10mM (DMSO)80.00€Darunavir Ethanolate
CAS:Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Formula:C29H43N3O8SPurity:99.84%Color and Shape:SolidMolecular weight:593.74Ref: TM-T3335
5mg37.00€10mg52.00€25mg80.00€50mg111.00€100mg165.00€200mg236.00€500mg399.00€1mL*10mM (DMSO)48.00€Picolamine
CAS:Picolamine acts as a potential inhibitor of DPP-4.Formula:C6H8N2Purity:99.64%Color and Shape:Light Yellow LiquidMolecular weight:108.14Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purity:98.05% - 99.95%Color and Shape:SolidMolecular weight:315.41Retagliptin Phosphate
CAS:Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.Formula:C19H21F6N4O7PPurity:98.70%Color and Shape:SolidMolecular weight:562.36Ref: TM-T12710
1mg35.00€2mg44.00€5mg64.00€10mg93.00€25mg170.00€50mg259.00€100mgTo inquire1mL*10mM (DMSO)84.00€Asunaprevir
CAS:Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.Formula:C35H46ClN5O9SPurity:99.34% - 99.8%Color and Shape:SolidMolecular weight:748.29Ref: TM-T4474
1mg52.00€5mg111.00€10mg180.00€25mg354.00€50mg540.00€100mg778.00€500mg1,605.00€1mL*10mM (DMSO)173.00€Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purity:98%Color and Shape:SolidMolecular weight:375.42Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purity:100% - 98.82%Color and Shape:SolidMolecular weight:767.86Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remainingFormula:C20H21N3O7SPurity:98.17%Color and Shape:SolidMolecular weight:447.46Tenofovir alafenamide
CAS:Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.Formula:C21H29N6O5PPurity:99% - 99.81%Color and Shape:SolidMolecular weight:476.47Stercobilin hydrochloride (mixture of isomers)
CAS:Stercobilin hydrochloride (mixture of isomers) is a bile pigment metabolized by intestinal bacteria and also acts as an inhibitor of HIV protease (HIVProtease) with a Ki of 4 μM. This compound can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (mixture of isomers) is utilized in research on inflammation and viral infections.Formula:C33H47ClN4O6Color and Shape:SolidMolecular weight:631.20o-Phenanthroline
CAS:o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-PhenanthrolineFormula:C12H8N2Purity:98.85%Color and Shape:SolidMolecular weight:180.21Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purity:98.7%Color and Shape:SolidMolecular weight:377.01HIV-IN-6
CAS:HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.Formula:C20H16N4O3SPurity:97.12%Color and Shape:SolidMolecular weight:392.43Enfuvirtide acetate
CAS:Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.Formula:C206H305N51O66Purity:99.34%Color and Shape:SolidMolecular weight:4552IDX184
CAS:IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3Formula:C25H35N6O9PSPurity:99.29%Color and Shape:SolidMolecular weight:626.62Samatasvir
CAS:Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.Formula:C47H48N8O6S2Purity:98.04%Color and Shape:SolidMolecular weight:885.06Ref: TM-T9567
1mg55.00€5mg116.00€10mg187.00€25mg376.00€50mg632.00€100mg1,008.00€1mL*10mM (DMSO)197.00€Rolipram
CAS:Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.Formula:C16H21NO3Purity:99.22% - 99.26%Color and Shape:SolidMolecular weight:275.34Dazcapistat
CAS:Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.Formula:C21H18FN3O4Purity:99.41%Color and Shape:SolidMolecular weight:395.38Ref: TM-T9710
1mg96.00€5mg202.00€10mg305.00€25mg550.00€50mg772.00€100mg1,074.00€1mL*10mM (DMSO)224.00€