Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2
CAS:Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate for the HIV-1 protease, facilitating the assessment of enzyme activity [1].Formula:C40H66N12O11Purity:98%Color and Shape:SolidMolecular weight:891.03Hinokiflavone
CAS:Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking theFormula:C30H18O10Purity:97.6% - 98.67%Color and Shape:SolidMolecular weight:538.46TTP-8307
CAS:TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Formula:C27H21FN4OPurity:99.14%Color and Shape:SolidMolecular weight:436.48Ref: TM-T13221
1mg105.00€5mg250.00€10mg401.00€25mg780.00€50mg1,169.00€100mg1,890.00€200mg2,547.00€1mL*10mM (DMSO)303.00€YH-306
CAS:YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.Formula:C19H18N2O2Purity:97.87%Color and Shape:SolidMolecular weight:306.36Platycodin D3
CAS:Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airwayFormula:C63H102O33Purity:98.91% - 99.69%Color and Shape:SolidMolecular weight:1387.46Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formula:C34H41N7O5Purity:98.19% - 99.12%Color and Shape:White PowderMolecular weight:627.73PMSF
CAS:Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acidFormula:C7H7FO2SPurity:97.75% - 99.9%Color and Shape:White To Cream SolidMolecular weight:174.194-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formula:C10H14O2Purity:98.64% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Formula:C25H23F6N5O4SPurity:≥98%Color and Shape:SolidMolecular weight:603.54Ref: TM-T16474
1mg127.00€5mg305.00€10mg492.00€25mg938.00€50mg1,454.00€100mg1,882.00€1mL*10mM (DMSO)406.00€Mavorixafor trihydrochloride
CAS:Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formula:C21H30Cl3N5Purity:98.00%Color and Shape:SolidMolecular weight:458.86UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Formula:C35H44N2O5Purity:98%Color and Shape:SolidMolecular weight:572.73Bellidifolin
CAS:Bellidoferin: anti-oxidant, protects liver, fights inflammation/tumors, aids nerve injury, blocks MAO A, may improve type-2 diabetes, antifungal.Formula:C14H10O6Purity:99.79% - 99.81%Color and Shape:SolidMolecular weight:274.23Ref: TM-T3822
1mg96.00€5mg225.00€10mg323.00€25mg537.00€50mg752.00€100mg1,035.00€1mL*10mM (DMSO)202.00€DS-1040 Tosylate
CAS:DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.Formula:C23H35N3O5SColor and Shape:SolidMolecular weight:465.61Talviraline
CAS:Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFormula:C15H20N2O3S2Purity:99.82%Color and Shape:SolidMolecular weight:340.462-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Formula:C5H3N3Purity:99.27%Color and Shape:Crystalline SolidMolecular weight:105.1CA inhibitor 1
CAS:CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.Formula:C41H36ClF8N7O5S2Purity:98%Color and Shape:SolidMolecular weight:958.34PF-3450074
CAS:PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Formula:C27H27N3O2Purity:99.92%Color and Shape:SolidMolecular weight:425.52Aderbasib
CAS:Aderbasib (INCB007839) is an ADAM10 and ADAM17 inhibitor with antitumor activity, used in cancer and cardiovascular disease research.Formula:C21H28N4O5Color and Shape:SolidMolecular weight:416.47Cystamine
CAS:Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM.Formula:C4H12N2S2Purity:99.41%Color and Shape:SolidMolecular weight:152.28Ceritinib
CAS:Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.Formula:C28H36ClN5O3SPurity:100% - 99.77%Color and Shape:SolidMolecular weight:558.14Bacoside A
CAS:Bacoside A shows potential anti-cancer effects, cytoprotection, EAE inhibition, and vasorelaxation abilities.Formula:C41H68O13Purity:98%Color and Shape:SolidMolecular weight:768.98E-64d [for Biochemical Research]
CAS:Formula:C17H30N2O5Purity:>95.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:342.44GS-9256
CAS:GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].Formula:C46H56ClF2N6O8PSPurity:98%Color and Shape:SolidMolecular weight:957.46Levovirin
CAS:Levovirin (L-Ribavirin) is a guanosine nucleoside analog that has immunomodulatory activity and is used in the study of hepatitis C virus infection.Formula:C8H12N4O5Purity:100% - 99.96%Color and Shape:SolidMolecular weight:244.203-Deazaadenosine hydrochloride
CAS:3-Deazaadenosine HCl blocks SAH hydrolase (Ki: 3.9 μM), with anti-inflammatory, anti-proliferative, and anti-HIV effects.Formula:C11H15ClN4O4Purity:98.48%Color and Shape:SolidMolecular weight:302.71Ref: TM-T10111
1mg126.00€5mg216.00€10mg374.00€25mg620.00€50mg868.00€100mg1,169.00€1mL*10mM (DMSO)149.00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s-MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurity:100% - 99.55%Color and Shape:Brown SolidMolecular weight:513.67Ref: TM-T6016
5mg51.00€10mg95.00€25mg160.00€50mg273.00€100mg492.00€200mg633.00€500mg998.00€1mL*10mM (DMSO)59.00€Epitheaflagallin 3-O-gallate
CAS:Epitheaflagallin 3-O-gallate: potential antiobesity, antiperiodontal agent; inhibits tumor growth by blocking angiogenesis.Formula:C27H20O13Purity:98%Color and Shape:SolidMolecular weight:552.44Aloesin
CAS:Aloesin, a C-glycosylated chromone from aloe, blocks tyrosinase (IC50=0.9mM) in melanin production.Formula:C19H22O9Purity:98% - 99.58%Color and Shape:SolidMolecular weight:394.37Collagenase Type V
Collagenase Type V, an endopeptidic matrix metalloproteinase MMP from the bacterium Clostridium histolyticum, can be used for islet tissue isolation.Color and Shape:Odour SolidTrichosanatine
CAS:Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein.Formula:C27H28N2O4Purity:98%Color and Shape:SolidMolecular weight:444.52Saikosaponin B2
CAS:Saikosaponin B2 inhibits HCV, blocks viral binding to hepatoma cells, and induces melanoma differentiation, enhancing tyrosinase and melanogenesis.Formula:C42H68O13Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:780.98Z-Gly-Pro-Arg-4MβNA
CAS:Z-Gly-Pro-Arg-4MβNA is a thrombin substrate that, upon cleavage by thrombin, releases 4-methoxy-2-naphthylamine (4MβNA).Formula:C32H39N7O6Purity:98%Color and Shape:SolidMolecular weight:617.7Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purity:100% - 99.87%Color and Shape:Crystalline SolidMolecular weight:282.33HIV-1 inhibitor-53
CAS:HIV-1 Inhibitor-53 targets HIV-1 protease (IC50: 1.93 nM) and reverse transcriptase (IC50: 2.35 μM), aiding AIDS research.Formula:C30H34N2O8SPurity:98%Color and Shape:SolidMolecular weight:582.66Nevirapine
CAS:Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Formula:C15H14N4OPurity:99.58% - 99.59%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:266.3Bestatin Hydrochloride
CAS:Formula:C16H25ClN2O4Purity:98%Color and Shape:SolidMolecular weight:344.8337CCR5 antagonist 1
CAS:CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formula:C39H46ClF2N5O3SPurity:98%Color and Shape:SolidMolecular weight:738.33Z-Pro-Pro-CHO
CAS:Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01Formula:C18H22N2O4Purity:98%Color and Shape:SolidMolecular weight:330.38Efegatran sulfate
CAS:Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.Formula:C21H34N6O7SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:514.6CM-352
CAS:CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Formula:C24H29N3O6SPurity:99.36%Color and Shape:SolidMolecular weight:487.57Dabigatran Etexilate Mesylate
CAS:Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.Formula:C34H41N7O5·CH4O3SPurity:99.91%Color and Shape:SolidMolecular weight:723.84Ref: TM-T5133
5mg42.00€10mg57.00€25mg74.00€50mg95.00€100mg111.00€200mg169.00€500mg240.00€1mL*10mM (DMSO)64.00€NM107
CAS:NM107, a ribonucleoside, inhibits HCV NS5B polymerase. It has broad antiviral properties with EC50 of 1.85 μM in wild-type cells.Formula:C10H15N3O5Purity:98%Color and Shape:White To Off-White PowderMolecular weight:257.24MRS1177
CAS:MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).Formula:C20H12ClN5O2Purity:98%Color and Shape:SolidMolecular weight:389.79Methyl rosmarinate
CAS:Methyl rosmarinate, from Rabdosia serra, inhibits tyrosinase (IC50: 0.28 mM), α-glucosidase, MMP-1, and has antioxidant, antifungal properties.Formula:C19H18O8Purity:97.52% - 99.62%Color and Shape:SolidMolecular weight:374.34Ref: TM-TN1928
1mg74.00€5mg165.00€10mg259.00€25mg435.00€50mg630.00€100mg880.00€1mL*10mM (DMSO)173.00€GLS1 Inhibitor-4
CAS:GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formula:C29H27F3N10O2S2Purity:98%Color and Shape:SolidMolecular weight:668.72Collagenase Type IV
Collagenase Type IV is an MMP-18 primarily degrades collagen type IV and VII and basement membranes (e.g., neural tissue, renal tissue) mild activity.Color and Shape:Odour SolidMirificin
CAS:Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.Formula:C26H28O13Purity:99.33% - 99.8%Color and Shape:SolidMolecular weight:548.49Ubenimex
CAS:Formula:C16H24N2O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:308.38Eltrombopag
CAS:Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the plateletFormula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.471,10-Phenanthroline Monohydrate [for Biochemical Research]
CAS:Formula:C12H8N2·H2OPurity:>99.0%(T)Color and Shape:White powder to crystalMolecular weight:198.23
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