
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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Fosamprenavir Calcium Salt
CAS:Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility.Formula:C25H34CaN3O9PSPurity:99.59%Color and Shape:White Microcrystalline NeedlesMolecular weight:623.67Nelfinavir Mesylate
CAS:Formula:C32H45N3O4S·CH4O3SPurity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:663.89Valopicitabine
CAS:Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronicFormula:C15H24N4O6Purity:98%Color and Shape:SolidMolecular weight:356.37(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.Formula:C33H44N6O5Purity:99.30%Color and Shape:SolidMolecular weight:604.74Ritonavir
CAS:Formula:C37H48N6O5S2Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalineMolecular weight:720.95gp120-α4β7 binding inhibitor 11
CAS:gp120-α4β7 binding inhibitor 11 is an anti-HIV agent.Formula:C26H27N3O2Purity:97.61%Color and Shape:SolidMolecular weight:413.51Ref: TM-T67737
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€200mg1,444.00€1mL*10mM (DMSO)278.00€Auraptene
CAS:Auraptene, a citrus-based coumarin with a C-7 geranyloxyl, has anti-inflammatory and anticancer properties, and inhibits BACE1, aiding Alzheimer's treatment.Formula:C19H22O3Purity:100% - 99.17%Color and Shape:SolidMolecular weight:298.38p-Hydroxycinnamic acid
CAS:p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-inducedFormula:C9H8O3Purity:99.67%Color and Shape:SolidMolecular weight:164.16(R)-MG-132
CAS:(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.Formula:C26H41N3O5Purity:98.45%Color and Shape:SolidMolecular weight:475.62Ref: TM-T12628
1g1,103.00€2mg40.00€5mg60.00€10mg84.00€25mg135.00€50mg216.00€100mg329.00€500mg797.00€1mL*10mM (DMSO)77.00€Z-VEID-FMK
CAS:Z-VEID-FMK is a selective caspase-6 peptide inhibitor that irreversibly covalently binds to the enzyme, thereby inhibiting apoptosis and DNA breakage.Formula:C31H45FN4O10Purity:98%Color and Shape:SolidMolecular weight:652.71TAPI-1 trifluoroacetate (163847-77-6(free base))
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.Formula:C28H38F3N5O7Purity:98.06%Color and Shape:SolidMolecular weight:613.62Sofosbuvir impurity L
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H29FN3O10PPurity:98%Color and Shape:SolidMolecular weight:545.45XL-784
CAS:XL-784 inhibits MMPs; IC50: 1900 nM (MMP-1), 0.81 nM (MMP-2), 120 nM (MMP-3), 10.8 nM (MMP-8), 18 nM (MMP-9), 0.56 nM (MMP-13).Formula:C42H46Cl2F4MgN6O16S2Purity:98%Color and Shape:SolidMolecular weight:1126.17Alloxan monohydrate
CAS:Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.Formula:C4H4N2O5Purity:99.01% - 99.42%Color and Shape:Off-White To Beige-Yellowish Crystalline PowderMolecular weight:160.09Avatrombopag
CAS:Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiationFormula:C29H34Cl2N6O3S2Purity:99.01% - 99.41%Color and Shape:SolidMolecular weight:649.65Ref: TM-T7417
1mg59.00€5mg120.00€10mg187.00€25mg339.00€50mg567.00€100mg810.00€200mg1,111.00€1mL*10mM (DMSO)170.00€Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Color and Shape:Odour SolidTerameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Dabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Formula:C25H25N7O3Purity:97.44% - 98.70%Color and Shape:Tan SolidMolecular weight:471.51ethyl rosmarinate
CAS:ethyl rosmarinate inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).Formula:C20H20O8Purity:98.82% - 99.65%Color and Shape:SolidMolecular weight:388.37Talabostat mesylate
CAS:Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.Formula:C10H23BN2O6SPurity:98% - 99.91%Color and Shape:SolidMolecular weight:310.18TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormula:C17H18ClNO3SPurity:97.33%Color and Shape:PowderMolecular weight:351.85Calycosin-7-O-β-D-glucoside
CAS:Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity.Formula:C22H22O10Purity:98% - 99.69%Color and Shape:SolidMolecular weight:446.4Ref: TM-T3388
1mg47.00€5mg92.00€10mg144.00€25mg254.00€50mg424.00€100mg613.00€500mg1,264.00€1mL*10mM (DMSO)97.00€BENZYLACETONE
CAS:Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties.Formula:C10H12OPurity:98.79%Color and Shape:Colourless LiquidMolecular weight:148.2XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formula:C23H24N6O2Purity:98.53% - 99.6%Color and Shape:SolidMolecular weight:416.48Ref: TM-T3710
1mg44.00€2mg56.00€5mg90.00€10mg144.00€25mg225.00€50mg415.00€100mg615.00€500mg1,311.00€1mL*10mM (DMSO)90.00€Antitrypanosomal agent 15
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4Formula:C21H19FN4O4Purity:98%Color and Shape:SolidMolecular weight:410.4Tetrahexyldecyl ascorbate
CAS:Tetrahexyldecyl ascorbate is a precursor of ascorbic acid, a more stable and permeable form of vitamin C. anti-hyperpigmentation antioxidant that inhibits MMP.Formula:C70H128O10Purity:98%Color and Shape:SolidMolecular weight:1129.767-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).Formula:C15H16N4Purity:99.22%Color and Shape:SolidMolecular weight:252.31MMP13-IN-5
MMP13-IN-5 (compound 13m) is a potent, selective MMP-2/MMP-13 inhibitor with IC50 values of 3.6 μM for MMP-2 and 14.6 μM for MMP-13, implicated in the pathologyFormula:C22H18BrN3O5Purity:98%Color and Shape:SolidMolecular weight:484.3Ro 31-9790
CAS:Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).Formula:C15H29N3O4Purity:98%Color and Shape:SolidMolecular weight:315.412-Methoxystypandrone
CAS:2-Methoxystypandrone modulates immunity, blocks inflammation, protects BBB, promotes neurogenesis, and inhibits bone resorption.Formula:C14H12O5Purity:98%Color and Shape:SolidMolecular weight:260.24Saquinavir mesylate
CAS:Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFormula:C39H54N6O8SPurity:99.19%Color and Shape:White Or Pale Yellow PowderMolecular weight:766.9T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53Ref: TM-T5416
1mg48.00€5mg96.00€10mg144.00€25mg254.00€50mg424.00€100mg627.00€200mg998.00€1mL*10mM (DMSO)107.00€3-Deazaadenosine
CAS:3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formula:C11H14N4O4Purity:98%Color and Shape:SolidMolecular weight:266.25NBD-556
CAS:NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.Formula:C17H24ClN3O2Purity:99.79%Color and Shape:SolidMolecular weight:337.84ZD8321
CAS:ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).Formula:C18H28F3N3O5Purity:98%Color and Shape:SolidMolecular weight:423.43Cerpegin
CAS:Cerpegin, a pyridine ketone fused c-lactone, acts as an inhibitor of the 20S proteasome. It possesses pharmacological properties as a neuropsychiatric sedative, anti-inflammatory, analgesic, and exhibits anti-ulcer activity.Formula:C10H11NO3Color and Shape:SolidMolecular weight:193.24-Phenoxybenzylamine
CAS:4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .Formula:C13H13NOPurity:≥95%Color and Shape:SolidMolecular weight:199.25Bemnifosbuvir
CAS:Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.Formula:C24H33FN7O7PPurity:98.34% - 99.35%Color and Shape:SolidMolecular weight:581.53Ref: TM-T9341
1mg65.00€5mg145.00€10mg238.00€25mg394.00€50mg562.00€100mg758.00€200mg1,017.00€1mL*10mM (DMSO)299.00€MMP-7-IN-3
CAS:MMP-7-IN-3 is a potent, selective MMP-7 inhibitor that effectively suppresses the progression of kidney fibrosis in a mouse model with unilateral ureteralFormula:C34H43ClF3N7O9SPurity:98%Color and Shape:SolidMolecular weight:818.263-Pyridylacetic acid hydrochloride
CAS:3-Pyridylacetic acid HCl (3-PAA) is a strong acid, reactive with amines/alcohols/acids, and an organic catalyst.Formula:C7H8ClNO2Purity:99.31% - 99.52%Color and Shape:White To Beige Crystalline PowderMolecular weight:173.6MMP-7-IN-2
CAS:MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17BAY-85-8501
CAS:BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)Formula:C22H17F3N4O3SPurity:99.16%Color and Shape:SolidMolecular weight:474.46Ref: TM-T12613L
1mg96.00€2mg128.00€5mg212.00€10mg314.00€25mg565.00€50mg792.00€100mg1,093.00€1mL*10mM (DMSO)220.00€2,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3S,4S,6S,9S)-
CAS:Formula:C37H48N6O5S2Purity:≥98%Color and Shape:SolidMolecular weight:720.9442Baceridin
CAS:Baceridin, a cyclic hexapeptide and proteasome inhibitor, can be isolated from the culture medium of Epiphytic Bacillus.Formula:C37H57N7O6Purity:98%Color and Shape:SolidMolecular weight:695.89Resiquimod
CAS:Resiquimod (R848) is a TLR7/TLR8 agonist. Resiquimod is an immunomodulator with antitumor and antiviral activity. Cost-effective and quality-assured.Formula:C17H22N4O2Purity:99.62% - 99.95%Color and Shape:SolidMolecular weight:314.38Ref: TM-T6964
5mg35.00€10mg51.00€25mg87.00€50mg137.00€100mg187.00€200mg250.00€500mg369.00€1mL*10mM (DMSO)50.00€Gemigliptin
CAS:Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)Formula:C18H19F8N5O2Purity:99.33%Color and Shape:SolidMolecular weight:489.36Ref: TM-T7369
2mg40.00€5mg60.00€10mg87.00€25mg157.00€50mg259.00€100mg406.00€500mg920.00€1mL*10mM (DMSO)88.00€Nelfinavir Mesylate
CAS:Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).Formula:C33H49N3O7S2Purity:95.81% - 98.27%Color and Shape:A White Or Almost White PowderMolecular weight:663.89Mergetpa
CAS:Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].Formula:C7H15N3O2S2Purity:98%Color and Shape:SolidMolecular weight:237.34β5i-IN-1
β5i-IN-1 is a selective inhibitor of β5i, exhibiting potent activity with an IC50 of 8.463 nM.Purity:98%Color and Shape:Odour Solid