
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:503.65Aprotinin
CAS:Aprotinin (Traskolan) is a broad-spectrum serine protease (BPTI) inhibitor. Aprotinin is an antifibrinolytic agent. Cost-effective and quality-assured.Formula:C284H432N84O79S7Purity:98%Color and Shape:SolidMolecular weight:6511.51Ledipasvir (acetone)
CAS:Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.Formula:C52H60F2N8O7Purity:99.72%Color and Shape:SolidMolecular weight:947.08Sofosbuvir impurity I
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C21H27FN3O9PPurity:98%Color and Shape:SolidMolecular weight:515.43Xanthyletin
CAS:Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.Formula:C14H12O3Purity:98.09% - 98.09%Color and Shape:SolidMolecular weight:228.24NS5A-IN-2
CAS:NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.Formula:C46H45N7O7Purity:98%Color and Shape:SolidMolecular weight:807.89NNGH
CAS:NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.Formula:C13H20N2O5SColor and Shape:SolidMolecular weight:316.37Odiparcil
CAS:Odiparcil is an orally active beta-d-thioxyloside analog.Formula:C15H16O6SPurity:98%Color and Shape:SolidMolecular weight:324.35Dermatan sulphate sodium
CAS:Dermatan sulphate sodium (Chondroitin sulfate B sodium salt) is a linear sulfated polysaccharide, a glycosaminoglycan component of several important proteoglycans, and an activating ligand for the kinase of mesenchymal lymphoma. Dermatan sulphate sodium is an anticoagulant, inhibiting thrombus Dermatan sulphate sodium is an anticoagulant that inhibits thrombosis.Color and Shape:SolidDoxycycline monohydrate
CAS:Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)Formula:C22H26N2O9Purity:98.87%Color and Shape:SolidMolecular weight:462.4Z-VEID-AFC
CAS:Z-VEID-AFC is a caspase-6 fluorescent substrate [1].Formula:C38H44F3N5O12Purity:98%Color and Shape:SolidMolecular weight:819.782-Iodoacetamide [for Biochemical Research]
CAS:Formula:C2H4INOPurity:>98.0%(N)Color and Shape:White to Light yellow powder to crystalMolecular weight:184.96KIN101
CAS:KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation.Formula:C16H11BrO5SPurity:99.46%Color and Shape:SolidMolecular weight:395.223,4-Dimethoxyphenol
CAS:3,4-Dimethoxyphenol (4-Hydroxyveratrole) is an active biochemical.Formula:C8H10O3Purity:98.57%Color and Shape:Red Crystal PowderMolecular weight:154.16KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Formula:C14H12BrN3OSPurity:98.52%Color and Shape:SolidMolecular weight:350.23Ref: TM-T27730
1mg103.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€200mg1,634.00€1mL*10mM (DMSO)259.00€Atevirdine
CAS:Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).Formula:C21H25N5O2Purity:98.75%Color and Shape:SolidMolecular weight:379.46Tegobuvir
CAS:Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.Formula:C25H14F7N5Purity:99.21%Color and Shape:SolidMolecular weight:517.4Ref: TM-T17029
1mg88.00€5mg187.00€10mg311.00€25mg532.00€50mg750.00€100mg1,035.00€1mL*10mM (DMSO)213.00€Calcium 2-oxoglutarate
CAS:Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).Formula:C5H8CaO5Purity:98%Color and Shape:SolidMolecular weight:188.192Leucodin
CAS:Leucodin may lower cholesterol, has anti-allergic properties, and inhibits beta-hexosaminidase release with an IC50 of 80µM.Formula:C15H18O3Purity:98%Color and Shape:SolidMolecular weight:246.3Etarotene
CAS:Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is aFormula:C25H32O2SPurity:100% - 100%Color and Shape:SolidMolecular weight:396.59LHVS
CAS:LHVS effectively blocks T.Formula:C28H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:527.68Ac-AAVALLPAVLLALLAP-YVAD-CHO
CAS:Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].Formula:C97H160N20O24Purity:98%Color and Shape:SolidMolecular weight:1990.43XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formula:C24H27N7O2Purity:97.12% - 97.61%Color and Shape:SolidMolecular weight:445.52Ref: TM-T3709
2mg47.00€5mg73.00€10mg103.00€25mg188.00€50mg306.00€100mg507.00€500mg1,225.00€1mL*10mM (DMSO)88.00€Tyrosinase-IN-33
CAS:Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Formula:C19H17NS2Color and Shape:SolidMolecular weight:323.48CDK9-IN-1
CAS:CDK9-IN-1 is a selective and potent CDK9 inhibitor with antiviral activity used in the study of PRRSV infections.Formula:C26H21N5O4SPurity:98.52%Color and Shape:SolidMolecular weight:499.54ZK824190
CAS:ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.Formula:C22H20F2N2O4Purity:98.84%Color and Shape:SolidMolecular weight:414.4Ref: TM-T13408
1mg259.00€5mg540.00€10mg775.00€25mg1,188.00€50mg1,596.00€100mg2,157.00€1mL*10mM (DMSO)560.00€OM-189
CAS:OM-189 is a selective inhibitor of synthetic thrombin.Formula:C24H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:488.65Tyrosinase-IN-37
CAS:Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Formula:C12H12N6SColor and Shape:SolidMolecular weight:272.33(Iso)-Z-VAD(OMe)-FMK
CAS:(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.Formula:C22H30FN3O7Purity:97.10%Color and Shape:SoildMolecular weight:467.49Mecarbinate
CAS:Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.Formula:C13H15NO3Purity:99.28%Color and Shape:Off-White Crystalline PowderMolecular weight:233.26K-7174 dihydrochloride
CAS:K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-Formula:C33H50Cl2N2O6Purity:99.15%Color and Shape:SolidMolecular weight:641.67Tenofovir diphosphate TEA
CAS:Tenofovir diphosphate TEA (TFV-DP TEA) is an ATP-competitive DNA polymerase inhibitor that inhibits HIV-1 reverse transcriptase that\has anti-HIV/HBV potential.Formula:C9H16N5O10P3·C6H15NPurity:93.45% - 98.51%Color and Shape:SolidMolecular weight:548.36Ethyl gallate
CAS:Ethyl gallate reduces breast cancer cell growth, invasion, and shows cytotoxicity via PI3K/Akt and MMPs pathway modulation; potential in cancer therapy.Formula:C9H10O5Purity:99.96%Color and Shape:White GranularMolecular weight:198.17CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.Formula:C54H75N13O16S2Purity:99.71%Color and Shape:SolidMolecular weight:1226.39BRD-810
BRD-810, a highly selective MCL1 inhibitor, binds to the MCL1 BH3 groove, impeding the sequestration of pro-apoptotic proteins and swiftly triggering caspase activation in MCL1-dependent cell lines. This compound exhibits anti-tumor efficacy in both blood cancer and solid tumor models.Formula:C39H44ClFN4O5Color and Shape:SolidMolecular weight:703.24Opaviraline
CAS:Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.Formula:C14H17FN2O3Purity:100%Color and Shape:SolidMolecular weight:280.29Ref: TM-T28255
1mg378.00€5mg922.00€10mg1,225.00€25mg1,853.00€50mg2,490.00€100mg3,353.00€1mL*10mM (DMSO)823.00€Azvudine
CAS:Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.Formula:C9H11FN6O4Purity:100% - 99.42%Color and Shape:SolidMolecular weight:286.22Ref: TM-T14489
1mg63.00€5mg136.00€10mg216.00€25mg425.00€50mg645.00€100mg944.00€200mg1,264.00€1mL*10mM (DMSO)129.00€Glycyrin
CAS:Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.Formula:C22H22O6Purity:98%Color and Shape:SolidMolecular weight:382.41MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formula:C20H37N3O4Purity:98% - ≥98%Color and Shape:SolidMolecular weight:383.53Lamivudine
CAS:Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.Formula:C8H11N3O3SPurity:100% - 99.56%Color and Shape:White Crystalline PowderMolecular weight:229.26Boc-AEVD-CHO
CAS:Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2].Formula:C22H36N4O10Purity:98%Color and Shape:SolidMolecular weight:516.54Pentosan Polysulfate Sodium (W/W 43%)
CAS:Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.Purity:98%Color and Shape:SolidMolecular weight:N/AArborinine
CAS:Arborinine exhibits antibacterial, anti-HCV (IC50: 6.4±0.7μg/ml), antifeedant, and cytotoxic properties, inducing apoptosis and cell cycle arrest.Formula:C16H15NO4Purity:98%Color and Shape:SolidMolecular weight:285.29NSC 185058
CAS:NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formula:C11H9N3SPurity:99.27%Color and Shape:SolidMolecular weight:215.27Swertiajaponin
CAS:Swertiajaponin possesses antimicrobial activity.Formula:C22H22O11Purity:99.83%Color and Shape:SolidMolecular weight:462.4PMEDAP
CAS:PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiencyFormula:C8H13N6O4PPurity:98.12%Color and Shape:SolidMolecular weight:288.2ML604440
CAS:ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.Formula:C17H24BF3N2O4Purity:97.06%Color and Shape:SolidMolecular weight:388.19Ref: TM-T12079
1mg120.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€200mg1,825.00€1mL*10mM (DMSO)301.00€Adafosbuvir PM
CAS:Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.Formula:C10H13FN2O6Purity:97.08%Color and Shape:SolidMolecular weight:276.22α-Arbutin
CAS:α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.Formula:C12H16O7Purity:99.82%Color and Shape:Solid PowderMolecular weight:272.25Dehydroeffusol
CAS:Dehydroeffusol: anti-cancer, anxiolytic, sedative; halts gastric cancer growth via ER stress and apoptosis.Formula:C17H14O2Purity:99.35%Color and Shape:SolidMolecular weight:250.29