
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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HIV-1 integrase inhibitor 8
CAS:HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].Formula:C21H24O2Purity:98.01%Color and Shape:SolidMolecular weight:308.41Monobenzone
CAS:Monobenzone (Benoquin) is a Depigmenting Agent.Formula:C13H12O2Purity:99.87%Color and Shape:Lustrous Leaflets From Water SolidMolecular weight:200.23Aclacinomycin A hydrochloride
CAS:Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (Formula:C42H54ClNO15Purity:98%Color and Shape:SolidMolecular weight:848.33Ref: TM-T10238
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire200mgTo inquire1mL*10mM (DMSO)To inquireVCH-916 free acid(1200133-34-1 free base)
CAS:VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.Formula:C26H37NO4SPurity:98.45%Color and Shape:SolidMolecular weight:459.64Ref: TM-TQ0122L
1mg74.00€2mg97.00€5mg140.00€10mg188.00€25mg339.00€50mg552.00€100mg792.00€1mL*10mM (DMSO)150.00€BI-1230
CAS:BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication.Formula:C42H52N6O9SPurity:98%Color and Shape:SolidMolecular weight:816.96TGase2-IN-1
CAS:TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Formula:C19H21F6N3OPurity:98%Color and Shape:SolidMolecular weight:421.38Temocapil
CAS:Temocapril is an inhibitor of tyrosine kinase.Formula:C23H28N2O5S2Purity:97.8%Color and Shape:White PowderMolecular weight:476.61IK-862
CAS:IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.Formula:C25H27N3O4Purity:98.72% - 99.39%Color and Shape:SolidMolecular weight:433.5MK-0608
CAS:MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).Formula:C12H16N4O4Purity:98.48%Color and Shape:SolidMolecular weight:280.28Ref: TM-T16088
1mg81.00€2mg96.00€5mg170.00€10mg274.00€25mg525.00€50mg753.00€100mg1,035.00€1mL*10mM (DMSO)183.00€Excisanin A
CAS:ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be aFormula:C20H30O5Purity:98%Color and Shape:SolidMolecular weight:350.45S 3304
CAS:S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.Formula:C24H20N2O4S2Purity:98.09%Color and Shape:SolidMolecular weight:464.56Ref: TM-T16966
1mg58.00€5mg160.00€10mg259.00€25mg429.00€50mg605.00€100mg815.00€200mg1,093.00€1mL*10mM (DMSO)163.00€Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formula:C25H17N7O2Purity:99.14%Color and Shape:SolidMolecular weight:447.45Ref: TM-T12715
1mg64.00€5mg131.00€10mg183.00€25mg311.00€50mg449.00€100mg615.00€200mg833.00€1mL*10mM (DMSO)143.00€MMP-9-IN-1
CAS:MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).Formula:C16H17F2N3O3SPurity:99.21%Color and Shape:SolidMolecular weight:369.39Ref: TM-T8310
1mg96.00€2mg139.00€5mg227.00€10mg359.00€25mg607.00€50mg847.00€100mg1,169.00€1mL*10mM (DMSO)221.00€ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99Teneligliptin
CAS:Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.58Ref: TM-T37522
1mgTo inquire5mg35.00€10mg52.00€25mg74.00€50mg97.00€100mg173.00€200mgTo inquire1mL*10mM (DMSO)50.00€Incyclinide
CAS:Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor.Formula:C19H17NO7Purity:97.99%Color and Shape:SolidMolecular weight:371.34Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Color and Shape:Odour SolidDabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purity:97.63%Color and Shape:SolidMolecular weight:499.56Diprotin A
CAS:Diprotin A (Ile-Pro-Ile) (Ile-Pro-Ile) is a dipeptidyl peptidase IV (DPP-IV) inhibitor.Formula:C17H31N3O4Purity:99.29%Color and Shape:White PowderMolecular weight:341.45Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formula:C20H24O11Purity:99.71% - 99.98%Color and Shape:White PowderMolecular weight:440.4Phepropeptin B
CAS:Phepropeptin B is a secondary metabolite derived from microorganisms, functioning as a proteasome (proteasome) inhibitor with an IC50 value of 11 μg/mL.Formula:C40H56N6O6Color and Shape:SolidMolecular weight:716.91Eltrombopag Olamine
CAS:Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietinFormula:C29H36N6O6Purity:99.59% - 99.89%Color and Shape:SolidMolecular weight:564.63Ref: TM-T6825
2mg43.00€5mg64.00€10mg90.00€25mg140.00€50mg177.00€100mg230.00€200mg340.00€500mg563.00€1mL*10mM (DMSO)90.00€MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purity:99%Color and Shape:SolidMolecular weight:407.46Ref: TM-T9090
1mg40.00€5mg80.00€10mg116.00€25mg212.00€50mg316.00€100mg447.00€200mg627.00€1mL*10mM (DMSO)96.00€Obefazimod
CAS:Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).Formula:C16H10ClF3N2OPurity:99.86%Color and Shape:SolidMolecular weight:338.71Ref: TM-T8311
2mg39.00€5mg62.00€10mg87.00€25mg187.00€50mg301.00€100mg437.00€200mg617.00€1mL*10mM (DMSO)65.00€Trovirdine
CAS:Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.Formula:C13H13BrN4SPurity:98.12% - 98.50%Color and Shape:SolidMolecular weight:337.24HZ-1157
CAS:HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.Formula:C12H16N4OPurity:98.23%Color and Shape:SolidMolecular weight:232.28UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Formula:C25H26N8O2S2Purity:97.44%Color and Shape:SolidMolecular weight:534.66Ginsenoside F4
CAS:Ginsenoside F4 induces apoptosis in JK cells by causing mitochondrial dysfunction and altering Bax and Bcl-2 levels.Formula:C42H70O12Purity:98%Color and Shape:SolidMolecular weight:767.01Feniralstat
CAS:Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.Formula:C26H25F2N5O4Purity:99.52%Color and Shape:SolidMolecular weight:509.51JG26
CAS:JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively,Formula:C19H22Br2N4O6SPurity:100.00% - 98.92%Color and Shape:SolidMolecular weight:594.27MMP2-IN-3
CAS:MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).Formula:C23H21N3OPurity:99.13%Color and Shape:SolidMolecular weight:355.43Ref: TM-T61271
1mg87.00€5mg192.00€10mg293.00€25mg477.00€50mg662.00€100mg889.00€200mg1,198.00€1mL*10mM (DMSO)205.00€Immunoproteasome activator 1
CAS:Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46Ledipasvir
CAS:Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.Formula:C49H54F2N8O6Purity:99.46%Color and Shape:SolidMolecular weight:889Ref: TM-T6200
1mg38.00€2mg49.00€5mg79.00€10mg88.00€25mg159.00€50mg256.00€100mg444.00€500mg1,017.00€1mL*10mM (DMSO)88.00€FK706
CAS:FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.Formula:C26H33F3N4NaO7Color and Shape:SolidMolecular weight:593.556CPA inhibitor
CAS:CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.Formula:C18H19NO4Purity:100%Color and Shape:SolidMolecular weight:313.35Ref: TM-T10876
1mg57.00€5mg125.00€10mg163.00€25mg278.00€50mg405.00€100mgTo inquire1mL*10mM (DMSO)138.00€Y-29794 Tosylate
CAS:Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.Formula:C30H42N2O4S3Purity:99.10%Color and Shape:SolidMolecular weight:590.86Ref: TM-T35233
1mg52.00€2mg74.00€5mg96.00€10mg137.00€25mg217.00€50mg391.00€100mg582.00€500mg1,254.00€1mL*10mM (DMSO)159.00€Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester, monomethanesulfonate
CAS:Formula:C17H27N3O7SPurity:98%Color and Shape:SolidMolecular weight:417.4772Gly-Pro-pNA hydrochloride
CAS:Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidaseFormula:C13H17ClN4O4Purity:99.41%Color and Shape:SolidMolecular weight:328.75BRD-6929
CAS:BRD-6929, a brain-targeted HDAC1/2 inhibitor (IC50 1/8 nM), enhances gnidimacrin's anti-HIV effect, useful in mood behavior studies.Formula:C19H17N3O2SPurity:99.05%Color and Shape:SolidMolecular weight:351.42Ref: TM-T10603
5mg50.00€10mg90.00€25mg170.00€50mg305.00€100mg442.00€200mg620.00€1mL*10mM (DMSO)51.00€Abietic Acid
CAS:Abietic Acid (Sylvic acid) is a diterpene extracted from Pimenta racemosavar. Cost-effective and quality-assured.Formula:C20H30O2Purity:90.59% - 92.6%Color and Shape:Physical Description Yellowish Resinous Powder (Ntp 1992)Molecular weight:302.45JNJ-10311795
CAS:JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.Formula:C40H35N2O6PPurity:99.19%Color and Shape:SolidMolecular weight:670.69ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Formula:C22H19N3O2SPurity:99.12% - 99.77%Color and Shape:SolidMolecular weight:389.47Ref: TM-T3423
1mg35.00€5mg80.00€10mg97.00€25mg188.00€50mg311.00€100mg500.00€500mg1,093.00€1mL*10mM (DMSO)88.00€Methyl 2-amino-5-bromobenzoate
CAS:Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is an HCV NS5b RNA polymerase inhibitor with antimicrobial activity.Formula:C8H8BrNO2Purity:98.05%Color and Shape:SolidMolecular weight:230.06L-Homocysteine
CAS:L-Homocysteine is a biological thiol associated with various diseases and conditions. It serves as a marker for atherosclerosis.Formula:C4H9NO2SPurity:99.91%Color and Shape:SolidMolecular weight:135.19Micrococcin P1
CAS:Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor(EC50 range of 0.1-0.5 μM)Formula:C48H49N13O9S6Purity:98%Color and Shape:SolidMolecular weight:1144.36Triolein
CAS:Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.Formula:C57H104O6Purity:98.28% - 99.99%Color and Shape:Clear Yellowish LiquidMolecular weight:885.43Paritaprevir free base
CAS:Paritaprevir (ABT-450) is an oral HCV NS3/NS4A protease inhibitor with potential against genotype 1, disrupting viral replication.Formula:C40H43N7O7SPurity:95% - 99.26%Color and Shape:SolidMolecular weight:765.89CGS 27023A
CAS:CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.Formula:C18H24ClN3O5SPurity:99.08%Color and Shape:SolidMolecular weight:429.92ZD-0892
CAS:ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).Formula:C24H32F3N3O5Purity:95% - 99.53%Color and Shape:SolidMolecular weight:499.52