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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Products of "Proteases/Proteasome"

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products per page.Found 857 products on this category.
  • PR 39 (porcine) acetate


    PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:N/A

    Ref: TM-TP1961L

    1mg
    187.00€
    5mg
    472.00€
    10mg
    708.00€
    25mg
    1,274.00€
    50mg
    1,898.00€
  • Dolutegravir sodium

    CAS:
    Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature
    Formula:C20H18F2N3NaO5
    Purity:98% - 99.74%
    Color and Shape:Solid
    Molecular weight:441.36

    Ref: TM-T2329

    1mg
    37.00€
    2mg
    52.00€
    5mg
    79.00€
    10mg
    111.00€
    25mg
    182.00€
    50mg
    274.00€
    100mg
    393.00€
    500mg
    895.00€
  • EDTA, Disodium Salt, Dihydrate

    CAS:
    EDTA disodium dihydrate chelates metals, inhibits proteases, and aids in protein purification; doesn't affect cellulase.
    Formula:C10H18N2Na2O10
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:372.24

    Ref: TM-T66155

    5g
    47.00€
  • Beclabuvir

    CAS:
    Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.
    Formula:C36H45N5O5S
    Purity:99.87% - 99.93%
    Color and Shape:Solid
    Molecular weight:659.84

    Ref: TM-T10493

    1mg
    135.00€
  • Sulochrin

    CAS:
    Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent
    Formula:C17H16O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:332.3

    Ref: TM-TN5079

    1mg
    460.00€
  • ISOGINKGETIN

    CAS:
    ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.
    Formula:C32H22O10
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:566.51

    Ref: TM-T4S21320

    5mg
    52.00€
  • Davelizomib

    CAS:
    Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].
    Formula:C21H26BF2N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.25

    Ref: TM-T79842

    ne
    Discontinued
    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product
  • Notoginsenoside T5

    CAS:
    TPNS from San-Chi root (Araliaceae) treats atherosclerosis by lowering lipids and modifying vascular CD40/MMP-9, suggesting clinical use.
    Formula:C41H68O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:752.983

    Ref: TM-TN1998

    5mg
    1,465.00€
  • Viscumneoside III

    CAS:
    Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.
    Formula:C27H32O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.53

    Ref: TM-TN2303

    1mg
    284.00€
  • Aloin

    CAS:
    Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
    Formula:C21H22O9
    Purity:98.28%
    Color and Shape:Yellow Powder
    Molecular weight:418.39

    Ref: TM-T2742

    50mg
    49.00€
    100mg
    60.00€
  • Mizoribine

    CAS:
    Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
    Formula:C9H13N3O6
    Purity:98.38% - 99.95%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:259.22

    Ref: TM-T1188

    5mg
    35.00€
    10mg
    49.00€
    25mg
    66.00€
    50mg
    93.00€
    100mg
    127.00€
    500mg
    304.00€
    1mL*10mM (DMSO)
    37.00€
  • Isatoribine

    CAS:
    Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.
    Formula:C10H12N4O6S
    Purity:100% - 99.73%
    Color and Shape:Solid
    Molecular weight:316.29

    Ref: TM-T24178

    1mg
    245.00€
    5mg
    610.00€
    10mg
    868.00€
    25mg
    1,301.00€
    50mg
    1,758.00€
    100mg
    2,375.00€
  • CIL62

    CAS:
    CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
    Formula:C23H26O5
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:382.45

    Ref: TM-T8468

    1mg
    52.00€
    5mg
    116.00€
    10mg
    170.00€
    25mg
    335.00€
    50mg
    562.00€
    100mg
    758.00€
    200mg
    1,017.00€
    1mL*10mM (DMSO)
    128.00€
  • HIV-1 Inhibitor 18A

    CAS:
    HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.
    Formula:C14H11N5O2S
    Purity:91.64%
    Color and Shape:Solid
    Molecular weight:313.33

    Ref: TM-T24141

    1mg
    115.00€
    5mg
    227.00€
    10mg
    313.00€
    25mg
    535.00€
    50mg
    752.00€
    100mg
    1,064.00€
    1mL*10mM (DMSO)
    217.00€
  • Sirpiglenastat

    CAS:
    Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.
    Formula:C22H27N5O5
    Purity:98.01% - 98.37%
    Color and Shape:Solid
    Molecular weight:441.48

    Ref: TM-T62560

    1mg
    298.00€
    5mg
    895.00€
    10mg
    1,568.00€
    25mg
    2,337.00€
    50mg
    3,155.00€
    100mg
    4,256.00€
  • Atazanavir Sulfate

    CAS:
    Formula:C38H52N6O7·H2SO4
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:802.94

    Ref: 3B-A3411

    100mg
    87.00€
    500mg
    295.00€
  • Melagatran

    CAS:
    Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.
    Formula:C22H31N5O4
    Purity:100% - 98.37%
    Color and Shape:Solid
    Molecular weight:429.51

    Ref: TM-T11994

    1mg
    513.00€
    5mg
    1,198.00€
    10mg
    1,549.00€
    25mg
    2,337.00€
    50mg
    3,125.00€
    100mg
    4,246.00€
    1mL*10mM (DMSO)
    1,130.00€
  • BMS-561392 Formic acid


    BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
    Formula:C28H34N4O6
    Purity:97.25%
    Color and Shape:Soild
    Molecular weight:522.59

    Ref: TM-T30531L

    1mg
    185.00€
    5mg
    424.00€
    10mg
    627.00€
    25mg
    938.00€
    50mg
    1,311.00€
    100mg
    1,795.00€
    500mg
    3,600.00€
    1mL*10mM (DMSO)
    520.00€
  • Pseudane IX

    CAS:
    Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.
    Formula:C18H25NO
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:271.4

    Ref: TM-T38375

    1mg
    185.00€
    5mg
    409.00€
    10mg
    605.00€
    25mg
    938.00€
    50mg
    1,293.00€
    100mg
    1,738.00€
  • TG2-IN-3h

    CAS:
    TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor
    Formula:C21H26N4O4S
    Purity:99.34% - 99.76%
    Color and Shape:Solid
    Molecular weight:430.52

    Ref: TM-T70413

    1mg
    279.00€
    5mg
    685.00€
    10mg
    938.00€
    25mg
    1,444.00€
  • MEGA-9

    CAS:
    MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.
    Formula:C16H33NO6
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:335.44

    Ref: TM-T20992

    50mg
    35.00€
    100mg
    49.00€
    200mg
    66.00€
  • Emtricitabine S-oxide

    CAS:
    Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.
    Formula:C8H10FN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.25

    Ref: TM-T11189

    1mg
    120.00€
    10mg
    903.00€
  • PSI

    CAS:
    PSI is a proteasome inhibitor.
    Formula:C32H50N4O8
    Purity:97% - 98.33%
    Color and Shape:Solid
    Molecular weight:618.76

    Ref: TM-T21510

    1mg
    87.00€
    5mg
    250.00€
    10mg
    424.00€
    25mg
    687.00€
    50mg
    947.00€
    100mg
    1,264.00€
  • Methylchloroisothiazolinone/Methylisothiazolinone Mixture

    CAS:
    Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.
    Formula:C8H9ClN2O2S2
    Color and Shape:Solid
    Molecular weight:264.75

    Ref: TM-T37963

    1g
    37.00€
  • Sovaprevir

    CAS:
    Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.
    Formula:C43H53N5O8S
    Purity:99.10%
    Color and Shape:Solid
    Molecular weight:799.97

    Ref: TM-T28830

    1mg
    266.00€
    5mg
    655.00€
    10mg
    934.00€
    25mg
    1,388.00€
    50mg
    1,872.00€
    100mg
    2,517.00€
    1mL*10mM (DMSO)
    1,035.00€
  • TS-021

    CAS:
    TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.
    Formula:C17H24FN3O5S
    Purity:100% - 100%
    Color and Shape:Solid
    Molecular weight:401.45

    Ref: TM-T29019

    1mg
    279.00€
    5mg
    685.00€
    10mg
    938.00€
    25mg
    1,444.00€
    50mg
    1,882.00€
  • RJF02215

    CAS:
    RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.
    Formula:C17H12ClN3OS3
    Color and Shape:Solid
    Molecular weight:405.95

    Ref: TM-T89894

    10mg
    To inquire
    50mg
    To inquire
  • Salicylanilide

    CAS:
    Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.
    Formula:C13H11NO2
    Purity:99.55%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:213.23

    Ref: TM-T0753

    10g
    34.00€
    1mL*10mM (DMSO)
    47.00€
  • hTYR/AbTYR-IN-1

    CAS:
    hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.
    Formula:C18H20N2O3
    Purity:99.59%
    Color and Shape:Soild
    Molecular weight:312.36

    Ref: TM-T77649

    5mg
    37.00€
    10mg
    57.00€
    25mg
    104.00€
    50mg
    153.00€
    100mg
    220.00€
    200mg
    321.00€
  • Heparin

    CAS:
    Heparin (Adomiparin) is a mucopolysaccharide sulfate that has shown partial anti-inflammatory activity in in vivo studies.
    Formula:C26H42N2O37S5
    Purity:98%
    Color and Shape:White Or Pale-Colored Amorphous Powder Solid
    Molecular weight:1134.9

    Ref: TM-T20654

    1mg
    93.00€
    5mg
    180.00€
    10mg
    269.00€
    25mg
    470.00€
    50mg
    705.00€
  • Oxindole

    CAS:
    Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.
    Formula:C8H7NO
    Purity:99.34%
    Color and Shape:Off-White Crystalline Powder
    Molecular weight:133.15

    Ref: TM-FR16741

    1g
    39.00€
    5g
    50.00€
    10g
    66.00€
  • TCH-165

    CAS:
    TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.
    Formula:C39H37N3O3
    Purity:98.2% - 98.75%
    Color and Shape:Solid
    Molecular weight:595.73

    Ref: TM-T17011

    1mg
    74.00€
    5mg
    160.00€
    10mg
    250.00€
    25mg
    455.00€
    50mg
    682.00€
    100mg
    938.00€
    1mL*10mM (DMSO)
    265.00€
  • KW-2450 Formate


    KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.
    Formula:C29H31N5O5S
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:561.65

    Ref: TM-T68405L

    1mg
    185.00€
    5mg
    459.00€
    10mg
    657.00€
    25mg
    1,026.00€
    50mg
    1,415.00€
    100mg
    1,872.00€
  • Thiamine disulfide

    CAS:
    Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.
    Formula:C24H34N8O4S2
    Purity:99.18%
    Color and Shape:Coa
    Molecular weight:562.71

    Ref: TM-T20062

    1g
    40.00€
    1mL*10mM (DMSO)
    34.00€
  • Chlorcyclizine

    CAS:
    CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.
    Formula:C18H21ClN2
    Purity:98% - 98.75%
    Color and Shape:Solid
    Molecular weight:300.83

    Ref: TM-T9717

    10mg
    35.00€
    25mg
    52.00€
    50mg
    66.00€
    100mg
    107.00€
    1mL*10mM (DMSO)
    97.00€
  • UK 356618

    CAS:
    UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
    Formula:C34H43N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:557.72

    Ref: TM-T17201

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
  • Cabotegravir

    CAS:
    Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (
    Formula:C19H17F2N3O5
    Purity:98.55% - 99.92%
    Color and Shape:Solid
    Molecular weight:405.35

    Ref: TM-T6098

    10mg
    50.00€
    25mg
    87.00€
    50mg
    156.00€
    100mg
    188.00€
  • Tyrosinase-IN-35

    CAS:
    Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.
    Formula:C17H15N5OS
    Color and Shape:Solid
    Molecular weight:337.40

    Ref: TM-T200078

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • DRB

    CAS:
    DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)
    Formula:C12H12Cl2N2O4
    Purity:99.46%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:319.14

    Ref: TM-T7789

    10mg
    40.00€
    25mg
    79.00€
    50mg
    96.00€
    100mg
    153.00€
  • Collagenase Type II


    Collagenase Type II, an endopeptidic MMP-8, preferentially degrades type I collagen tissues requiring high digestive efficiency pancreas and liver.
    Color and Shape:Odour Solid

    Ref: TM-T201393

    25mg
    38.00€
    50mg
    57.00€
    100mg
    93.00€
  • U18666A

    CAS:
    U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor.
    Formula:C25H42ClNO2
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:424.06

    Ref: TM-T17190

    1mg
    35.00€
    2mg
    47.00€
    5mg
    70.00€
    10mg
    97.00€
    25mg
    185.00€
    50mg
    301.00€
    100mg
    454.00€
    200mg
    650.00€
    1mL*10mM (DMSO)
    77.00€
  • CASP3 Activator 1541

    CAS:
    CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.
    Formula:C24H17N3O4
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:411.41

    Ref: TM-T8652

    1mg
    52.00€
    5mg
    111.00€
    10mg
    180.00€
    25mg
    376.00€
    50mg
    605.00€
    100mg
    938.00€
    200mg
    1,301.00€
  • L 756423

    CAS:
    L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.
    Formula:C39H48N4O5
    Purity:100% - 100%
    Color and Shape:Solid
    Molecular weight:652.82

    Ref: TM-T24362

    1mg
    370.00€
    5mg
    882.00€
    10mg
    1,198.00€
    25mg
    1,786.00€
    50mg
    2,403.00€
    100mg
    3,250.00€
  • Illomastat

    CAS:
    Formula:C20H28N4O4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:388.4607

    Ref: IN-DA00350G

    5mg
    66.00€
    10mg
    102.00€
    25mg
    140.00€
    50mg
    181.00€
    100mg
    345.00€
    250mg
    519.00€
  • TAPI1

    CAS:
    TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
    Formula:C26H37N5O5
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:499.6

    Ref: TM-T6009

    1mg
    187.00€
  • Setrobuvir

    CAS:
    Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with
    Formula:C25H25FN4O6S2
    Purity:100% - 99%
    Color and Shape:Solid
    Molecular weight:560.62

    Ref: TM-T28762

    1mg
    229.00€
    5mg
    570.00€
    10mg
    812.00€
    25mg
    1,216.00€
    50mg
    1,663.00€
    100mg
    2,242.00€
    500mg
    4,494.00€
    1mL*10mM (DMSO)
    737.00€
  • Efavirenz

    CAS:
    Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.
    Formula:C14H9ClF3NO2
    Purity:99.2% - 99.83%
    Color and Shape:White To Slightly Pink Crystalline Powder
    Molecular weight:315.67

    Ref: TM-T2393

    1g
    404.00€
    5mg
    42.00€
    10mg
    52.00€
    25mg
    71.00€
    50mg
    89.00€
    100mg
    116.00€
    500mg
    273.00€
    1mL*10mM (DMSO)
    49.00€
  • Doxycycline hydrochloride

    CAS:
    Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.
    Formula:C22H24N2O8·HCl
    Purity:98.77%
    Color and Shape:Yellow Hygroscopic Crystalline Powder
    Molecular weight:480.9

    Ref: TM-T1140

    10mg
    35.00€
    25mg
    49.00€
    50mg
    66.00€
    100mg
    95.00€
    500mg
    169.00€
  • Atazanavir

    CAS:
    Formula:C38H52N6O7
    Purity:>95.0%(HPLC)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:704.87

    Ref: 3B-A3469

    5g
    188.00€
  • Mk-6186 HCl


    MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.
    Formula:C21H13Cl3N6O
    Purity:98.19%
    Color and Shape:Soild
    Molecular weight:471.73

    Ref: TM-T68103L

    1mg
    185.00€
    5mg
    442.00€
    10mg
    645.00€
    25mg
    1,017.00€
    50mg
    1,359.00€
    100mg
    1,833.00€