Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
Show 4 more subcategories
Products of "Proteases/Proteasome"
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lavendustin B
CAS:Lavendustin B inhibits Tyrosine Kinase and HIV-1 integrase-LEDGF/p75 interaction.Formula:C21H19NO5Purity:95.72%Color and Shape:Off-White SolidMolecular weight:365.38Ref: TM-T4182
1mg62.00€2mg87.00€5mg119.00€10mg188.00€25mg425.00€50mg625.00€100mg892.00€1mL*10mM (DMSO)131.00€AMD 3465
CAS:AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formula:C24H38N6Purity:98%Color and Shape:SolidMolecular weight:410.60ARP-100
CAS:ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM).Formula:C17H20N2O5SPurity:98.24%Color and Shape:SolidMolecular weight:364.426-Hydroxykaempferol
CAS:6-Hydroxykaempferol, a competitive tyrosinase inhibitor, a flavonoid, and a natural product, has higher activity than L-DOPA and high antioxidant activity.Formula:C15H10O7Purity:98%Color and Shape:SolidMolecular weight:302.24NS5A-IN-3
CAS:NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.Formula:C44H44N6O8Purity:98%Color and Shape:SolidMolecular weight:784.86Bivalirudin
CAS:Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clottingFormula:C98H138N24O33Purity:100.00% - 98.8%Color and Shape:White To Off-White PowderMolecular weight:2180.29Cynaropicrin
CAS:Cynaropicrin is a sesquiterpene lactone found in artichoke with anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.Formula:C19H22O6Purity:96.15%Color and Shape:SolidMolecular weight:346.37Didanosine
CAS:Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).Formula:C10H12N4O3Purity:99.64%Color and Shape:White Crystalline PowderMolecular weight:236.23M867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Formula:C27H43N7O6Purity:98%Color and Shape:SolidMolecular weight:561.67Proteasome-IN-1
CAS:Proteasome-IN-1 is an inhibitor of proteasome.Formula:C42H35N5O3Purity:98%Color and Shape:SolidMolecular weight:657.76MG-115
CAS:MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formula:C25H39N3O5Purity:97.12%Color and Shape:White PowderMolecular weight:461.592'-MeCCPA
CAS:2'-MeCCPA is an A1AR agonist that inhibits trichothecene-stimulated adenylate cyclase activity and has analgesic activity for the study of HCV.Formula:C16H22ClN5O4Purity:99.93%Color and Shape:SolidMolecular weight:383.83Sofosbuvir impurity A
CAS:Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride (1:1)
CAS:Formula:C8H11ClFNO2SPurity:98%Color and Shape:SolidMolecular weight:239.6948CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.Formula:C19H31N3O6Purity:97.26% - 99.58%Color and Shape:SolidMolecular weight:397.47Ref: TM-T3420
1mg59.00€2mg79.00€5mg115.00€10mg178.00€25mg360.00€50mg532.00€100mg743.00€200mg1,026.00€1mL*10mM (DMSO)96.00€Sivelestat Sodium Tetrahydrate
CAS:Formula:C20H21N2NaO7S·4H2OPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:528.50Z-Ala-Ala-Asp-CMK
CAS:Z-Ala-Ala-Asp-chloromethylketone (Z-AAD-CMK) is a selective inhibitor of granzyme B [1].Formula:C19H24ClN3O7Purity:98%Color and Shape:SolidMolecular weight:441.86HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formula:C27H30N6O4SPurity:97.61% - 98.61%Color and Shape:SoildMolecular weight:534.63Menadione
CAS:Menadione (Vitamin K3) is a synthetic naphthoquinone, inactive but converts to active Vitamin K2 in vivo.Formula:C11H8O2Purity:99.08% - 99.41%Color and Shape:Bright Yellow Crystals SolidMolecular weight:172.18JTE-607
CAS:JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.Formula:C25H33Cl4N3O5Purity:97.88%Color and Shape:SolidMolecular weight:597.36Ref: TM-T27695
1mg44.00€2mg57.00€5mg87.00€10mg159.00€25mg328.00€50mg558.00€100mg797.00€1mL*10mM (DMSO)115.00€(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:458.38Torilin
CAS:Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49BT1718
CAS:BT1718 is a bicyclic peptide conjugate that targets MT1-MMP, a protease overexpressed in various advanced solid tumors such as triple-negative breast cancer (Formula:C159H218ClN31O47S5Purity:98%Color and Shape:SolidMolecular weight:3511.39MMP-2/MMP-9 Inhibitor I
CAS:MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.Formula:C21H19NO4SPurity:99.74%Color and Shape:SolidMolecular weight:381.44Ref: TM-T21512
1mg59.00€5mg126.00€10mg187.00€25mg376.00€50mg622.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)169.00€Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.45HCV-IN-29
CAS:HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.Formula:C26H32Cl4N6Purity:99.66%Color and Shape:SolidMolecular weight:570.38Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43Daclatasvir
CAS:Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.Formula:C40H50N8O6Purity:99.81%Color and Shape:SolidMolecular weight:738.88MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purity:99.06%Color and Shape:SolidMolecular weight:441.95Hck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Formula:C16H11ClN6O3SPurity:99.07%Color and Shape:SolidMolecular weight:402.81Ref: TM-T11538
1mg97.00€5mg216.00€10mg344.00€25mg567.00€50mg825.00€100mg1,121.00€200mg1,510.00€1mL*10mM (DMSO)240.00€AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purity:99.39%Color and Shape:SolidMolecular weight:896.07Hirudin
CAS:Hirudin is an anticoagulant extracted from leeches, a thrombin inhibitor, used in diabetic nephropathy research.Formula:C66H93N13O25Purity:99.75%Color and Shape:SolidMolecular weight:1468.52Ref: TM-T126366
1mg180.00€5mg449.00€10mg655.00€25mg1,026.00€50mg1,388.00€100mg1,872.00€200mg2,527.00€Fosdevirine
CAS:Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological related diseasesFormula:C20H17ClN3O3PPurity:99.94%Color and Shape:SolidMolecular weight:413.79Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57MMP-9-IN-7
CAS:N-[2-[(5-Cl-2-methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide inhibits pro-MMP activation, treats MMP9/MMP13 syndromes.Formula:C16H15ClN4O2S2Purity:97.35%Color and Shape:SolidMolecular weight:394.9Ref: TM-T72069
1mg64.00€5mg131.00€10mg188.00€25mg325.00€50mg487.00€100mg708.00€500mg1,483.00€1mL*10mM (DMSO)131.00€Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurity:99.96%Color and Shape:SolidMolecular weight:591.55Ref: TM-TQ0223
1mg74.00€2mg96.00€5mg165.00€10mg255.00€25mg492.00€50mg715.00€100mg1,008.00€1mL*10mM (DMSO)208.00€Aloin(mixture of A&B)
CAS:ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.Formula:C21H22O9Purity:99.36%Color and Shape:SolidMolecular weight:418.39Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFormula:C135H196F3N51O35Purity:98%Color and Shape:SolidMolecular weight:3150.32Acetohydroxamic acid
CAS:Acetohydroxamic acid (N-Hydroxyacetamide) is an antagonist of the bacterial enzyme urease.Formula:C2H5NO2Purity:99.82% - 99.91%Color and Shape:SolidMolecular weight:75.07Capillarisin
CAS:Capillarisin blocks STAT3, inhibits osteosarcoma growth via apoptosis, arrests cell cycle, and has anti-inflammatory, anti-hyperalgesic properties.Formula:C16H12O7Purity:98%Color and Shape:SolidMolecular weight:316.26Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Formula:C13H15NO6SPurity:99.69%Color and Shape:SolidMolecular weight:313.33CK-666
CAS:CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.Formula:C18H17FN2OPurity:99.93%Color and Shape:SolidMolecular weight:296.34Ref: TM-T10826
1mg40.00€5mg87.00€10mg140.00€25mg281.00€50mg545.00€100mg755.00€200mg945.00€1mL*10mM (DMSO)95.00€PSI-6130
CAS:PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.Formula:C10H14FN3O4Purity:98.63% - 98.88%Color and Shape:SolidMolecular weight:259.23Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formula:C27H30ClN7O3Purity:99.65%Color and Shape:SolidMolecular weight:536.03Acetyl-binankadsurin A
CAS:Acetyl-binankadsurin A (compound 5), a lignan obtained from Kadsura longipedunculata, exhibits weak inhibitory effects on HIV-1 protease, demonstrating an IC50Formula:C24H28O8Purity:98%Color and Shape:SolidMolecular weight:444.47Norepinephrine
CAS:Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway.Formula:C8H11NO3Purity:98.56% - 99.84%Color and Shape:Colorless Micr°Crystals SolidMolecular weight:169.18Histatin 5 acetate
Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.Formula:C135H199N51O35Purity:98.72%Color and Shape:SolidMolecular weight:3096.35HCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Formula:C36H44N6O4Purity:98.77%Color and Shape:SolidMolecular weight:624.77Narlaprevir
CAS:Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.Formula:C36H61N5O7SPurity:98%Color and Shape:SolidMolecular weight:707.96
