Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- STAT
- Stem Cells
- TGF-beta/Smad
- Wnt/beta-catenin
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Products of "Stem Cell and Derivatives"
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Ilginatinib hydrochloride
CAS:Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H21ClFN7Purity:99.55%Color and Shape:SolidMolecular weight:425.89Ref: TM-T12266L2
1mg77.00€5mg165.00€10mg240.00€25mg408.00€50mg562.00€100mg800.00€200mg1,074.00€1mL*10mM (DMSO)177.00€CUR61414
CAS:CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM).Formula:C31H42N4O5Purity:97.34% - 98.00%Color and Shape:SolidMolecular weight:550.69Ref: TM-T15019
1mg52.00€5mg111.00€10mg180.00€25mg359.00€50mg550.00€100mg787.00€1mL*10mM (DMSO)123.00€LSKL TFA
CAS:LSKL TFA (H-Leu-Ser-Lys-Leu-NH2 TFA) is a TGF-尾1 antagonist that inhibits TSP-1 binding to LAP and reduces renal interstitial fibrosis and liver fibrosis.Formula:C23H43F3N6O7Purity:99.33%Color and Shape:SolidMolecular weight:572.62CCG 203769
CAS:CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.Formula:C8H14N2O2SPurity:99.46%Color and Shape:SolidMolecular weight:202.27Ref: TM-T10705
1mg88.00€5mg187.00€10mg264.00€25mg469.00€50mg657.00€100mg944.00€500mg1,882.00€1mL*10mM (DMSO)207.00€DIF-3
CAS:DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Formula:C13H17ClO4Purity:99.57%Color and Shape:SolidMolecular weight:272.72Ref: TM-T60485
1mg92.00€5mg235.00€10mg350.00€25mg588.00€50mg838.00€100mg1,130.00€500mg2,308.00€1mL*10mM (DMSO)215.00€2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2SAG 21k
CAS:SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.Formula:C29H28ClF2N3O2SPurity:99.51%Color and Shape:SolidMolecular weight:556.07BMP signaling agonist sb4
CAS:BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)Formula:C14H10BrNOSPurity:99.48% - 99.94%Color and Shape:SolidMolecular weight:320.2Ref: TM-T7799
5mg47.00€10mg60.00€25mg88.00€50mg126.00€100mg187.00€200mg283.00€500mg490.00€1mL*10mM (DMSO)50.00€β-catenin modulator IIa-661
CAS:β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.Formula:C19H23ClN2O3SPurity:99.53%Color and Shape:SoildMolecular weight:394.92JAK3-IN-6
CAS:JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormula:C19H18N4O3Purity:97.46% - 99.94%Color and Shape:SolidMolecular weight:350.37Cenacitinib
CAS:Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.Formula:C19H19F2N7O3Color and Shape:SolidMolecular weight:431.40JAK/HDAC-IN-2
JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.Formula:C28H38N6O5SPurity:98%Color and Shape:SolidMolecular weight:570.7ARN25068
CAS:ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.Formula:C19H18N6SPurity:99.71%Color and Shape:SolidMolecular weight:362.45ELN318463 racemate
CAS:ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.Formula:C19H20BrClN2O3SPurity:99.73%Color and Shape:SolidMolecular weight:471.8Ref: TM-T11178L
1mg162.00€5mg391.00€10mg615.00€25mg907.00€50mg1,235.00€100mg1,663.00€1mL*10mM (DMSO)447.00€JAK2-IN-6
CAS:JAK2-IN-6: A potent JAK2-specific inhibitor (IC50=22.86μg/mL), blocks JAK2 signaling, has anticancer properties, and is inactive against JAK1/3.Formula:C14H10ClN3OS2Purity:99.38%Color and Shape:SolidMolecular weight:335.83SRI-011381
CAS:SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H31N3OPurity:98.64%Color and Shape:SolidMolecular weight:329.48Ref: TM-T4283
1mg35.00€2mg48.00€5mg70.00€10mg111.00€25mg227.00€50mg378.00€100mg622.00€200mg873.00€500mg1,293.00€1mL*10mM (DMSO)49.00€Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Formula:C18H16O4Purity:99.94%Color and Shape:SolidMolecular weight:296.32Ref: TM-T17256
2mg34.00€5mg52.00€10mg80.00€25mg131.00€50mg212.00€100mg316.00€200mg454.00€1mL*10mM (DMSO)52.00€Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formula:C22H26N8Purity:99.82%Color and Shape:SolidMolecular weight:402.50Ref: TM-T35898
1mg88.00€5mg187.00€10mg298.00€25mg597.00€50mg938.00€100mg1,510.00€200mg2,072.00€1mL*10mM (DMSO)207.00€NSC 370284
CAS:NSC 370284 inhibits STAT3/5, reducing AML cell viability with TET1 overexpression in vitro/in vivo.Formula:C21H25NO6Purity:96.16%Color and Shape:SolidMolecular weight:387.43Ref: TM-T9949
5mg70.00€10mg119.00€25mg250.00€50mg424.00€100mg627.00€500mg1,320.00€1mL*10mM (DMSO)77.00€JNJ-1289
CAS:JNJ-1289: potent hSMOX inhibitor, IC50 50 nM, potential for anticancer/anti-inflammatory research.Formula:C16H12N4OSPurity:98.16%Color and Shape:SolidMolecular weight:308.36
