Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- STAT
- Stem Cells
- TGF-beta/Smad
- Wnt/beta-catenin
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Products of "Stem Cell and Derivatives"
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AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Formula:C21H23N7O3SPurity:98% - 99.25%Color and Shape:SolidMolecular weight:453.52Ref: TM-T1957
1mg38.00€2mg49.00€5mg79.00€10mg106.00€25mg198.00€50mg374.00€100mg555.00€500mg1,206.00€1mL*10mM (DMSO)108.00€RU-SKI 43
CAS:RU-SKI 43: Potent, selective Hhat inhibitor, IC50 850 nM. Anticancer; potential lung adenocarcinoma treatment. Inhibits Gli-1, Akt, mTOR pathways.Formula:C22H30N2O2SPurity:99.78%Color and Shape:SolidMolecular weight:386.55Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Formula:C12H10ClN7Purity:99.45%Color and Shape:SolidMolecular weight:287.71Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.23%Color and Shape:SolidMolecular weight:482SMANT hydrochloride
CAS:SMANT hydrochloride (N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride) is an antagonist of Smoothened accumulation.Formula:C16H24BrClN2OPurity:100%Color and Shape:SolidMolecular weight:375.73Disitertide acetate
Disitertide acetate: a TGF-β1 and PI3K blocker, promotes apoptosis; inhibits receptor interaction.Formula:C70H113N17O24S2Purity:95.11%Color and Shape:SoildMolecular weight:1640.88IWP-3
CAS:IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Formula:C22H17FN4O2S3Purity:98.38%Color and Shape:SolidMolecular weight:484.59GSK180736A
CAS:GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).Formula:C19H16FN5O2Purity:98.16% - 98.44%Color and Shape:SolidMolecular weight:365.36Ref: TM-T3513
1mg42.00€2mg52.00€5mg73.00€10mg88.00€25mg170.00€50mg306.00€100mg568.00€500mg1,225.00€1mL*10mM (DMSO)65.00€Tolnaftate
CAS:Tolnaftate (NP-27) is a synthetic antifungal agent.Formula:C19H17NOSPurity:98.85%Color and Shape:White PowderMolecular weight:307.41MSC-4106
CAS:MSC-4106, an oral YAP/TAZ-TEAD inhibitor, blocks TEAD1/3 auto-palmitoylation and suppresses NCI-H226 tumors.Formula:C18H12F3N3O2Purity:100%Color and Shape:SoildMolecular weight:359.3Ref: TM-T60148
1mg96.00€5mg235.00€10mg378.00€25mg630.00€50mg898.00€100mg1,216.00€200mg1,634.00€1mL*10mM (DMSO)271.00€Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg44.00€2mg55.00€5mg79.00€10mg106.00€25mg185.00€50mg283.00€100mg432.00€200mg605.00€500mg938.00€1mL*10mM (DMSO)86.00€Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49TAK-901
CAS:TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFormula:C28H32N4O3SPurity:97.38% - 99.1%Color and Shape:SolidMolecular weight:504.64AR-A014418
CAS:AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.Formula:C12H12N4O4SPurity:99.94% - ≥95%Color and Shape:SolidMolecular weight:308.31Aloisine B
CAS:Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Formula:C15H14ClN3Purity:95.15%Color and Shape:SolidMolecular weight:271.74Tubastatin
CAS:Tubastatin inhibits TGF-β1-induced S6K phosphorylation, HIF-1α expression and VEG F expression.Formula:C21H22N2O2Purity:98.23%Color and Shape:SolidMolecular weight:334.41Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purity:100% - 99.74%Color and Shape:SolidMolecular weight:346.42Ref: TM-T4672
1mg96.00€5mg215.00€10mg369.00€25mg610.00€50mg840.00€100mg1,130.00€500mg2,308.00€1mL*10mM (DMSO)235.00€PIMPC
CAS:PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibitsFormula:C21H19N5OPurity:98%Color and Shape:SolidMolecular weight:357.41Rhodblock 6
CAS:Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Formula:C12H13N3OPurity:98.27%Color and Shape:SolidMolecular weight:215.25Wnt/β-catenin agonist 2
CAS:Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist.Formula:C13H12N4O3Purity:99.58%Color and Shape:SolidMolecular weight:272.26Ref: TM-T41094
1mg54.00€5mg116.00€10mg187.00€25mg318.00€50mg449.00€100mg638.00€500mg1,264.00€1mL*10mM (DMSO)111.00€
