Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Products of "Wnt/beta-catenin"
Sort by
BML-284 hydrochloride
CAS:BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.Formula:C19H19ClN4O3Purity:99.80%Color and Shape:SolidMolecular weight:386.84Ref: TM-T8820
1mg35.00€5mg67.00€10mg88.00€25mg150.00€50mg266.00€100mg462.00€200mg648.00€500mg1,017.00€1mL*10mM (DMSO)89.00€Wnt-C59
CAS:Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.Formula:C25H21N3OPurity:99.56% - 99.95%Color and Shape:SolidMolecular weight:379.45TNIK-IN-2
CAS:TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.Formula:C22H19N3O3Purity:98.09%Color and Shape:SolidMolecular weight:373.4Hematein
CAS:Hematein blocks Akt/PKB, Wnt signaling, promotes apoptosis in lung cancer, is a dye from hematoxylin, and inhibits casein kinase II (IC50: 0.74 μM).Formula:C16H12O6Purity:98%Color and Shape:Dark Brown Crystalline PowderMolecular weight:300.26ABC99
CAS:ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formula:C22H21ClN4O5Purity:98.65%Color and Shape:SoildMolecular weight:456.88Ref: TM-T23602
1mg172.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)354.00€Tabituximab
CAS:BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Color and Shape:LiquidMolecular weight:145.5 kDaHLY78
CAS:HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.Formula:C17H17NO2Purity:99.58%Color and Shape:SolidMolecular weight:267.32JW 67
CAS:JW 67 is an inhibitor of canonical Wnt pathway signaling.Formula:C21H18N2O6Purity:97.02%Color and Shape:SolidMolecular weight:394.38Ref: TM-T22884
1mg46.00€2mg59.00€5mg87.00€10mg137.00€25mg273.00€50mg439.00€100mg647.00€1mL*10mM (DMSO)97.00€IWP-3
CAS:IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Formula:C22H17FN4O2S3Purity:98.38%Color and Shape:SolidMolecular weight:484.59Teplinovivint
CAS:Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathyFormula:C25H26N6O2Purity:97.21%Color and Shape:SolidMolecular weight:442.51TNIK-IN-5
CAS:TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formula:C22H17N3O3Purity:99.75%Color and Shape:SolidMolecular weight:371.39FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Ref: TM-T2413
5mg38.00€10mg57.00€25mg94.00€50mg164.00€100mg274.00€200mg404.00€500mg653.00€1mL*10mM (DMSO)64.00€Miclxin
CAS:Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potentFormula:C26H27N5O2Purity:100% - 99.57%Color and Shape:SolidMolecular weight:441.52Ref: TM-T73415
1mg64.00€5mg140.00€10mg192.00€25mg324.00€50mg452.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)156.00€FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formula:C21H16N2O2SPurity:99.37% - 99.89%Color and Shape:SolidMolecular weight:360.43Ref: TM-T24076
1mg42.00€5mg64.00€10mg99.00€25mg188.00€50mg328.00€100mg528.00€500mg1,130.00€1mL*10mM (DMSO)62.00€Toxoflavin
CAS:Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A.Formula:C7H7N5O2Purity:98.24% - 99.7%Color and Shape:SolidMolecular weight:193.16Wnt/β-catenin agonist 3
CAS:Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.Formula:C16H15ClN4O2Purity:99.39%Color and Shape:SolidMolecular weight:330.77Ref: TM-T9988
5mg74.00€10mg107.00€25mg216.00€50mg354.00€100mg567.00€200mg800.00€500mg1,198.00€1mL*10mM (DMSO)81.00€PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.Formula:C33H35N6O7PPurity:98.25% - 99.11%Color and Shape:SoildMolecular weight:658.641(R),2(S)-epoxy Cannabidiol
CAS:1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46Wnt/β-catenin agonist 4
CAS:Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.Formula:C16H15FN4O2Purity:99.61%Color and Shape:SolidMolecular weight:314.31Ref: TM-T60803
1mg35.00€5mg70.00€10mg103.00€25mg182.00€50mg311.00€100mg512.00€200mg720.00€1mL*10mM (DMSO)81.00€IWR-1
CAS:IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).Formula:C25H19N3O3Purity:98.46% - 99.82%Color and Shape:SolidMolecular weight:409.44
