Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK
- c-Fms
- c-Kit
- c-Met/HGFR
- c-RET
- CSF-1R
- EGFR
- Ephrin Receptor
- Fibroblast Growth Factor Receptor (FGFR)
- FLT
- Hck
- HER
- IGF-1R
- PDGFR
- PYK2
- Src
- TAM Receptor
- Tie-2
- Trk receptor
- Tyrosine Kinases
- VEGFR
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Products of "Tyrosine Kinase/Adaptors"
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PD 0325901
CAS:Formula:C16H14F3IN2O4Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:482.20Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03BMS-935177
CAS:BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.Formula:C31H26N4O3Purity:99.89%Color and Shape:SolidMolecular weight:502.56Chamigrenal
CAS:β-Chamigrenal: Anti-inflammatory, inhibits NO and PGE2 in macrophages, PAF antagonist (IC50=1.2x10^-4 M), weakly cytotoxic to MCF-7 (IC50=30.50 uM).Formula:C15H22OPurity:99.31%Color and Shape:SolidMolecular weight:218.33FLT3-IN-10
CAS:FLT3-IN-10, a potent FLT3 inhibitor, may treat FLT3-mutated AML.Formula:C15H11FN2OPurity:99.60%Color and Shape:SolidMolecular weight:254.26Ref: TM-T9856
1mg38.00€5mg85.00€10mg131.00€25mg259.00€50mg383.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)81.00€Protein kinase G inhibitor-1
CAS:Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.Formula:C14H18N2O2SPurity:98.11%Color and Shape:SoildMolecular weight:278.37Ref: TM-T67755
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€200mg1,444.00€1mL*10mM (DMSO)235.00€Compound TPX-0046
CAS:Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.Formula:C21H21FN6O3Purity:99.85%Color and Shape:SoildMolecular weight:424.43Fazpilodemab
CAS:Fazpilodemab (BFKB8488A) is a humanized bispecific antibody that targets and activates the Klotho β and fibroblast growth factor receptor 1c receptor complex.Color and Shape:Liquid(S)-Afatinib
CAS:(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formula:C24H25ClFN5O3Purity:100% - 99.96%Color and Shape:Off-White SolidMolecular weight:485.94Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:100% - 98.55%Color and Shape:SolidMolecular weight:557.04Btk inhibitor 2
CAS:Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor.Formula:C24H25N5O3Purity:99.94%Color and Shape:SolidMolecular weight:431.49Ref: TM-T10629
1mg37.00€2mg52.00€5mg79.00€10mg103.00€25mg227.00€50mg376.00€100mg457.00€1mL*10mM (DMSO)87.00€Glesatinib hydrochloride
CAS:Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.Formula:C31H28ClF2N5O3S2Purity:98%Color and Shape:SolidMolecular weight:656.16ALK-IN-5
CAS:ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).Formula:C24H25FN6O3Purity:98%Color and Shape:SolidMolecular weight:464.49FGFR3-IN-6
CAS:FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].Formula:C25H23FN8O2Purity:98%Color and Shape:SolidMolecular weight:486.5Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formula:C27H28ClFN6OColor and Shape:SolidMolecular weight:507Amivantamab (FUT8-KO)
Amivantamab (FUT8-KO) is a humanized dual-specificity antibody targeting EGFR-MET, exhibiting immunotherapeutic anticancer activity. This compound inhibits ligand binding, enhances the internalization and degradation of receptor-antibody complexes, and stimulates macrophage-mediated phagocytosis and natural killer cell cytotoxicity, both of which are Fc-dependent.Formula:C13H12O4Color and Shape:LiquidMolecular weight:232.23DDR Inhibitor
CAS:DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.Formula:C23H20FN5O2Purity:97.75%Color and Shape:SolidMolecular weight:417.44Ref: TM-T10985
1mg116.00€5mg235.00€10mg378.00€25mg758.00€50mg1,206.00€100mg1,634.00€1mL*10mM (DMSO)259.00€EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Formula:C18H23N5NaO8PPurity:96.56% - 99.76%Color and Shape:White PowderMolecular weight:491.37
