Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK
- c-Fms
- c-Kit
- c-Met/HGFR
- c-RET
- CSF-1R
- EGFR
- Ephrin Receptor
- Fibroblast Growth Factor Receptor (FGFR)
- FLT
- Hck
- HER
- IGF-1R
- PDGFR
- PYK2
- Src
- TAM Receptor
- Tie-2
- Trk receptor
- Tyrosine Kinases
- VEGFR
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Products of "Tyrosine Kinase/Adaptors"
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TL13-22
CAS:TL13-22 is a potent inhibitor of ALK and does not lead to degradation of ALK proteins.TL13-22 is often used as a negative control for TL13-12 .Formula:C45H55ClN10O9SPurity:99.13%Color and Shape:SolidMolecular weight:947.5TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purity:99.37%Color and Shape:SolidMolecular weight:445.47Ref: TM-T16975
2mg44.00€5mg65.00€10mg101.00€25mg192.00€50mg299.00€100mg432.00€200mg607.00€1mL*10mM (DMSO)77.00€OD36 hydrochloride
CAS:OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficientlyFormula:C16H16Cl2N4O2Purity:99.85%Color and Shape:SolidMolecular weight:367.23MRX-2843
CAS:MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).Formula:C29H40N6OPurity:99.63%Color and Shape:SolidMolecular weight:488.67Ref: TM-T16144
1mg65.00€5mg144.00€10mg227.00€25mg454.00€50mg655.00€100mg933.00€1mL*10mM (DMSO)157.00€CHMFL-EGFR-202
CAS:CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).Formula:C25H24ClN7O2Purity:99.19%Color and Shape:SolidMolecular weight:489.96Ref: TM-T10802
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)305.00€(2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide
CAS:Formula:C18H16N2O3Purity:97%Color and Shape:SolidMolecular weight:308.33124000000004GW297361
CAS:GW297361 is a potent inhibitor of the cell cycle protein-dependent kinase Cdk1 and also inhibits the Pho85 signaling pathway.The IC50s of GW297361 on yeast Cdk1Formula:C16H12N4O3S2Purity:97.02%Color and Shape:SolidMolecular weight:372.42TG 100801
CAS:TG 100801 is a dual inhibitor of VEGFr2 and Src family kinases and is a candidate compound for the treatment of age-related macular degeneration (AMD).Formula:C33H30ClN5O3Purity:100% - 99.61%Color and Shape:SolidMolecular weight:580.08LFM-A13
CAS:Formula:C11H8Br2N2O2Purity:>98.0%(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:360.01BMS-599626 2HCL(714971-09-2 Free base)
CAS:BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative.Formula:C27H29Cl2FN8O3Purity:99.11%Color and Shape:Odour SolidMolecular weight:603.47Ref: TM-T2610L
1mg94.00€5mg150.00€10mg284.00€25mg487.00€50mg705.00€100mg998.00€1mL*10mM (DMSO)334.00€Tafetinib
CAS:Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity.Formula:C24H29FN4O2Purity:96.66%Color and Shape:SolidMolecular weight:424.51Pyrithyldione
CAS:Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Formula:C9H13NO2Color and Shape:SolidMolecular weight:167.21Vislarafusp alfa
Vislarafusp alfa is a humanized IgG1κ antibody that targets EGFR/CD47, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidCinrebafusp alfa
CAS:Cinrebafusp alfa (PRS 343) is an anticalin-based bispecific drug with high affinity for both CD137/HER2, displaying dissociation constants (Kd) of 0.3 nM toPurity:98%Color and Shape:LiquidUniPR500
CAS:UniPR500, a derivative of UniPR129, is a competitive antagonist for the EphA2 receptor, with a Ki of 0.78 μM. It reduces the binding of biotinylated Ephrin-A1 to EphA2 in a dose-dependent manner, exhibiting an IC50 value of 1.1 μM.Formula:C36H51N3O4Color and Shape:SolidMolecular weight:589.808IBT6A
CAS:IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurity:99.8% - 99.88%Color and Shape:SolidMolecular weight:386.45Tyrphostin A9
CAS:Formula:C18H22N2OPurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:282.39AMPK-IN-3
CAS:AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.Formula:C25H33N5O3Purity:99.13%Color and Shape:SolidMolecular weight:451.56WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purity:99.21%Color and Shape:SolidMolecular weight:297.31
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