Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
Products of "Fibroblast Growth Factor Receptor (FGFR)"
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FGFR3-IN-7
CAS:FGFR3-IN-7 is a potent, selective inhibitor of FGFR 3, demonstrating an IC50 value of less than 350 nM , and is utilized in cancer research [1].Formula:C25H24FN9OPurity:98%Color and Shape:SolidMolecular weight:485.52SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32Fazpilodemab
CAS:Fazpilodemab (BFKB8488A) is a humanized agonistic bispecific antibody that targets fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ.Purity:98%Color and Shape:LiquidAZD4547
CAS:AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formula:C26H33N5O3Purity:99.37% - 99.88%Color and Shape:SolidMolecular weight:463.57Ref: TM-T1948
2mg39.00€5mg49.00€10mg63.00€25mg88.00€50mg113.00€100mg156.00€200mg219.00€500mg366.00€1mL*10mM (DMSO)55.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:419.48FGFR1 inhibitor-9
FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor with potent binding affinity, exhibiting an IC50 of 0.85 nM.Formula:C27H20ClNO5Purity:98%Color and Shape:SolidMolecular weight:473.9Infigratinib
CAS:Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 andFormula:C26H31Cl2N7O3Purity:98% - 98.97%Color and Shape:SolidMolecular weight:560.48FGFR-IN-15
FGFR-IN-15 (compound 18i) acts as a pan-FGFR inhibitor, exhibiting potent inhibitory activity against FGFR1-4.Formula:C22H23N5O5SColor and Shape:SolidMolecular weight:469.51Heparan Sulfate
CAS:Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG). Cost effective and quality assured.Formula:C12H19NO20S3(monomer)Purity:98%Color and Shape:SolidMolecular weight:593.47(monomer)SU4984
CAS:SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formula:C20H19N3O2Purity:100%Color and Shape:SolidMolecular weight:333.38FGFR1 inhibitor-10
CAS:FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation.Formula:C26H30F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:561.62PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.7%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg39.00€2mg49.00€5mg66.00€10mg89.00€25mg155.00€50mg222.00€100mg310.00€1mL*10mM (DMSO)56.00€PP58
CAS:PP58 is an inhibitor of PDGFR, FGFR and Src family.Formula:C22H19Cl2N5O2Purity:99.21%Color and Shape:SolidMolecular weight:456.32FGFR1 inhibitor 7
FGFR1 Inhibitor 7 (compound 5), a potent FGFR1 tyrosine kinase inhibitor, exhibits an IC50 of 0.33 nM against its target and demonstrates broad-spectrumFormula:C25H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:429.85PD-161570
CAS:Formula:C26H35Cl2N7OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:532.51FGFR3-IN-6
CAS:FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].Formula:C25H23FN8O2Purity:98%Color and Shape:SolidMolecular weight:486.5FGFR1 inhibitor-16
CAS:FGFR1inhibitor-16 (Compound 89) functions as an FGFR1 inhibitor, demonstrating an inhibition rate of 53.00% at a concentration of 50 μM and 24.95% at 10 μM. It is utilized in tumor research.Formula:C16H9N5O3SColor and Shape:SolidMolecular weight:351.339Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Roblitinib
CAS:Roblitinib (FGF-401), an FGFR4 inhibitor, potentially blocks tumor growth by halting cell proliferation and survival.Formula:C25H30N8O4Purity:97.27% - 99%Color and Shape:SolidMolecular weight:506.56Ref: TM-T4235
1mg58.00€2mg84.00€5mg103.00€10mg169.00€25mg306.00€50mg535.00€100mg752.00€500mg1,586.00€Nintedanib
CAS:Formula:C31H33N5O4Purity:>95.0%(T)(HPLC)Color and Shape:White to Yellow to Yellow green powder to crystalMolecular weight:539.64
