VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Ref: TM-T2500
2mg42.00€5mg63.00€10mg92.00€25mg136.00€50mg177.00€100mg254.00€200mg462.00€500mg742.00€1mL*10mM (DMSO)69.00€ZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purity:100%Color and Shape:SolidMolecular weight:411.86Ansornitinib
CAS:Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.Formula:C30H32N6O4Color and Shape:SolidMolecular weight:540.61MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38Axitinib
CAS:Formula:C22H18N4OSPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:386.47PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFormula:C25H20Cl2N2O3Purity:99.19%Color and Shape:SolidMolecular weight:467.34Ref: TM-T12574
1mg117.00€5mg243.00€10mg369.00€25mg622.00€50mg885.00€100mg1,206.00€1mL*10mM (DMSO)250.00€BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purity:97.71% - 99.36%Color and Shape:SolidMolecular weight:439.39JK-P3
CAS:Formula:C18H17N3O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:323.35PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67Ref: TM-T2642
5mg43.00€10mg57.00€25mg89.00€50mg140.00€100mg221.00€200mg393.00€500mg655.00€1mL*10mM (DMSO)59.00€Riddelline
CAS:Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.Formula:C18H23NO6Purity:98%Color and Shape:SolidMolecular weight:349.38Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody (4D988)
Anti-VEGFR2/KDR Antibody (4D988) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4D988) can be used in ELISA.Color and Shape:Odour LiquidZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).Formula:C16H13ClFN3O2Purity:99.31% - ≥95%Color and Shape:SolidMolecular weight:333.74Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.21% - 99.39%Color and Shape:SolidMolecular weight:246.3Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purity:95.4% (SEC-HPLC) - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:146.53 kDaRef: TM-T9904
1mg127.00€2mg202.00€5mg376.00€10mg560.00€25mg895.00€50mg1,216.00€100mg1,634.00€200mg2,213.00€Dovitinib Dilactic Acid
CAS:Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.Formula:C21H21FN6O·2C3H6O3Purity:98%Color and Shape:SolidMolecular weight:572.59Carvedilol
CAS:Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.Formula:C24H26N2O4Purity:99.73% - 99.88%Color and Shape:Colourless Crystalline PowderMolecular weight:406.47Ref: TM-T0447
25mgTo inquire50mgTo inquire100mgTo inquire200mgTo inquire500mgTo inquire1mL*10mM (DMSO)To inquireIMPDH2-IN-4
IMPDH2-IN-4 (compound 2d) is a Mycophenolic acid analog and a selective IMPDH2 inhibitor with a Ki of 1.8 μM. It exhibits potent cytotoxic activity against osteosarcoma cancer cell lines. Additionally, IMPDH2-IN-4 demonstrates high affinity for VEGFR-2, CDK2, and IMPDH.Formula:C35H34O6SiColor and Shape:SolidMolecular weight:578.73Coumarin-3-carboxylic acid
CAS:The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/Formula:C10H6O4Purity:99.88%Color and Shape:Light Brown Crystalline PowderMolecular weight:190.15
