VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "VEGFR"
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PKI-166
CAS:PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.Formula:C20H18N4OPurity:99.76%Color and Shape:SolidMolecular weight:330.38Ref: TM-T16549
1mg42.00€5mg119.00€10mg188.00€25mg376.00€50mg628.00€100mg1,008.00€200mg1,349.00€1mL*10mM (DMSO)131.00€VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4Pamufetinib
CAS:Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.Formula:C27H23FN4O4SPurity:99.39%Color and Shape:SolidMolecular weight:518.56Ref: TM-T13108
1mg50.00€5mg106.00€10mg158.00€25mg258.00€50mg379.00€100mg538.00€200mg733.00€1mL*10mM (DMSO)134.00€SYHA1815
CAS:SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.Formula:C27H26ClF4N5OColor and Shape:SolidMolecular weight:547.98Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Ref: TM-T2656
2mg35.00€5mg52.00€10mg85.00€25mg117.00€50mg147.00€100mg250.00€500mg620.00€1mL*10mM (DMSO)58.00€ODM-203 sodium
ODM-203 sodium is an orally bioavailable selective and efficient FGFR and VEGFR inhibitor with antitumor activity, used in solid tumor research.Formula:C26H20F2N5NaO2SPurity:99.89%Color and Shape:SolidMolecular weight:527.52VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:84.6 kDa (predicted)JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79Ref: TM-T22349
1mg52.00€2mg74.00€5mg105.00€10mg156.00€25mg259.00€50mg378.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)113.00€Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.Formula:C15H14N2OPurity:99.84%Color and Shape:Yellow To Yellow OrangeMolecular weight:238.28Anti-VEGFR2/KDR Antibody-APC (5U735)
Anti-VEGFR2/KDR Antibody-APC (5U735) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (5U735) can be used in FCM.Color and Shape:Odour LiquidVGX100
VGX100 is a humanized antibody targeting VEGFC for the study of solid tumors.Color and Shape:LiquidMolecular weight:145.5Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.Formula:C21H20ClFN2OSPurity:98%Color and Shape:SolidMolecular weight:402.91CP-547632 TFA
CAS:CP-547632 TFA, an oral VEGFR-2 and FGF inhibitor, IC50: VEGFR-2 at 11 nM, FGF at 9 nM, shows antitumor activity.Formula:C22H25BrF5N5O5SPurity:98%Color and Shape:SolidMolecular weight:646.43(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurity:100% - 98.13%Color and Shape:SolidMolecular weight:329.17Ref: TM-T23554
2mg35.00€5mg52.00€10mg81.00€25mg138.00€50mg215.00€100mg329.00€200mg464.00€1mL*10mM (DMSO)52.00€SU 4981
CAS:SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.Formula:C19H18N2O2Purity:100%Color and Shape:SoildMolecular weight:306.36Ref: TM-T60094
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)248.00€Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formula:C26H21F3N4O4Purity:98.98% - 99.39%Color and Shape:SolidMolecular weight:510.46PD 173074
CAS:Formula:C28H41N7O3Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:523.68RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Ref: TM-T6296
1mg47.00€2mg63.00€5mg87.00€10mg147.00€25mg266.00€50mg435.00€100mg640.00€1mL*10mM (DMSO)99.00€Ramucirumab
CAS:Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.Formula:C285H434N74O88S2Purity:99.2% (SEC-HPLC) - 99.20%Color and Shape:LiquidMolecular weight:143.77 kDaMotesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purity:99.76%Color and Shape:SolidMolecular weight:569.44
