FLT
FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Products of "FLT"
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JTV-519 free base
CAS:JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmicFormula:C25H32N2O2SPurity:98%Color and Shape:SolidMolecular weight:424.6MRX-2843
CAS:MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).Formula:C29H40N6OPurity:99.63%Color and Shape:SolidMolecular weight:488.67Ref: TM-T16144
1mg65.00€5mg144.00€10mg227.00€25mg454.00€50mg655.00€100mg933.00€1mL*10mM (DMSO)157.00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurity:96.13% - 98.95%Color and Shape:SolidMolecular weight:624.42Ref: TM-T2605
1mg47.00€2mg55.00€5mg88.00€10mg124.00€25mg221.00€50mg374.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)116.00€3-Hydroxy Midostaurin
CAS:3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM inFormula:C35H30N4O5Purity:98%Color and Shape:SolidMolecular weight:586.648OTS447
CAS:OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .Formula:C27H32ClN3O2Purity:97.72%Color and Shape:SolidMolecular weight:466.027BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.Formula:C16H10BrN3O2Purity:99.77%Color and Shape:SolidMolecular weight:356.17Ref: TM-T22012
5mg46.00€10mg64.00€25mg116.00€50mg178.00€100mg284.00€200mg401.00€1mL*10mM (DMSO)52.00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formula:C23H26FN6O9PPurity:93.08% - 99.38%Color and Shape:SolidMolecular weight:580.46Ref: TM-T6115
1mg43.00€2mg57.00€5mg88.00€10mg118.00€25mg210.00€50mg335.00€100mg548.00€500mg1,198.00€1mL*10mM (DMSO)101.00€FN-1501
CAS:FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).Formula:C22H25N9OPurity:96.35%Color and Shape:SolidMolecular weight:431.49Ref: TM-T15335
1mg92.00€5mg187.00€10mg311.00€25mg567.00€50mg852.00€100mg1,159.00€1mL*10mM (DMSO)215.00€JAK3-IN-14
CAS:JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.Formula:C18H13N3OPurity:98.98%Color and Shape:SoildMolecular weight:287.32Ref: TM-T67754
1mg215.00€5mg620.00€10mg904.00€25mg1,320.00€50mg1,786.00€100mg2,432.00€1mL*10mM (DMSO)540.00€FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.GTP-14564
CAS:GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.Formula:C15H10N2OPurity:99.69%Color and Shape:SolidMolecular weight:234.25AMG 925
CAS:AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.Formula:C26H29N7O2Purity:99.75%Color and Shape:SolidMolecular weight:471.55(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurity:97% - 98.03%Color and Shape:SolidMolecular weight:372.46Ref: TM-T21503
1mg46.00€2mg59.00€5mg87.00€10mg119.00€25mg210.00€50mg349.00€100mg507.00€1mL*10mM (DMSO)96.00€SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formula:C25H27N7O3S2Purity:100% - 98.27%Color and Shape:SolidMolecular weight:537.66Ref: TM-T2051
1mg66.00€2mg87.00€5mg131.00€10mg187.00€25mg393.00€50mg587.00€100mg835.00€500mg1,700.00€1mL*10mM (DMSO)157.00€FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.Purity:97.5%Color and Shape:Lyophilized PowderMolecular weight:35.6 kDa (predicted)AKN-028
CAS:AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.Formula:C17H14N6Purity:97.3%Color and Shape:SolidMolecular weight:302.33FLT1 Protein, Human, Recombinant (hFc)
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:61.1 kDa (predicted)
