c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Products of "c-Kit"
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BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formula:C27H29FN10OPurity:99.67%Color and Shape:SolidMolecular weight:528.58Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:97.16% - 99.37%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg47.00€5mg96.00€10mg154.00€25mg283.00€50mg464.00€100mg740.00€200mg1,008.00€1mL*10mM (DMSO)96.00€Anti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Color and Shape:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Color and Shape:Odour Liquidc-Kit Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purity:97.1%Color and Shape:Lyophilized PowderMolecular weight:82 kDa (predicted); 93-115 kDa (reducing conditions)Anti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Color and Shape:Odour LiquidBezuclastinib
CAS:Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.Formula:C19H17N5OPurity:99.81%Color and Shape:SolidMolecular weight:331.37AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Formula:C21H21FN6OPurity:99.66% - 99.78%Color and Shape:SolidMolecular weight:392.43Ref: TM-T6289
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg328.00€200mg490.00€500mg783.00€1mL*10mM (DMSO)50.00€KG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Formula:C20H16F3N7OSPurity:98.2%Color and Shape:SolidMolecular weight:459.45Ref: TM-T41003
1mg34.00€2mg47.00€5mg74.00€10mg105.00€25mg205.00€50mg313.00€100mg449.00€200mg628.00€1mL*10mM (DMSO)89.00€Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purity:98.34% - 99.51%Color and Shape:SolidMolecular weight:417.81Ref: TM-T2115
5mg48.00€10mg62.00€25mg95.00€50mg120.00€100mg154.00€200mg202.00€500mg350.00€1mL*10mM (DMSO)52.00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:96.25%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg90.00€5mg187.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€1mL*10mM (DMSO)215.00€Anti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Color and Shape:Odour LiquidMulti-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purity:99.34%Color and Shape:SolidMolecular weight:418.37CHMFL-ABL/KIT-155
CAS:CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).Formula:C33H38F3N5O3Purity:98%Color and Shape:SolidMolecular weight:609.68CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.2%Color and Shape:Lyophilized PowderMolecular weight:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Color and Shape:Odour LiquidDovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Formula:C19H21N3O2SPurity:98.39%Color and Shape:SolidMolecular weight:355.45
