c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Products of "c-Kit"
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Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg50.00€10mg85.00€25mg126.00€50mg188.00€100mg274.00€200mg505.00€500mg815.00€1mL*10mM (DMSO)52.00€Anti-C-Kit Antibody (7P530)
Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.Color and Shape:Odour Liquidc-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formula:C26H21F2N5O3Purity:98.16% - 98.72%Color and Shape:SolidMolecular weight:489.47Ref: TM-T4332
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg304.00€50mg542.00€100mg778.00€500mg1,605.00€1mL*10mM (DMSO)94.00€Protein kinase inhibitor 10
CAS:Protein kinase inhibitor 10 is a protein kinase inhibitor with IC50 values of 28.9 μM, 13.6 μM, and 2.41 μM for TAM receptors, FAK, and KIT, respectively. It can inhibit abnormal and excessive cell proliferation, showing potential for research in the field of cancer treatment.Formula:C14H9FN6S2Color and Shape:SolidMolecular weight:344.39Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98%Color and Shape:SolidMolecular weight:494.45c-Kit-IN-8
CAS:C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 μM. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 μM.Formula:C24H26FN5O4Color and Shape:SolidMolecular weight:467.49Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purity:100% - 97.67%Color and Shape:SolidMolecular weight:594.75Ref: TM-T8544
5mg35.00€10mg51.00€25mg77.00€50mg95.00€100mg144.00€200mg225.00€500mg373.00€1mL*10mM (DMSO)49.00€Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07%Color and Shape:SolidMolecular weight:510.36Ref: TM-T8482
1mg80.00€5mg167.00€10mg281.00€25mg500.00€50mg727.00€100mg1,198.00€200mg1,596.00€1mL*10mM (DMSO)213.00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Ref: TM-T5164
1mg44.00€2mg55.00€5mg69.00€10mg97.00€25mg169.00€50mg248.00€100mg349.00€200mg568.00€500mg908.00€c-Kit-IN-2
CAS:c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (Formula:C25H29N9O2SPurity:98%Color and Shape:SolidMolecular weight:519.62c-Kit Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:99.4%Color and Shape:Lyophilized PowderMolecular weight:56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formula:C20H16ClN5O3Purity:97.61% - 99.81%Color and Shape:SolidMolecular weight:409.83JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79Ref: TM-T22349
1mg52.00€2mg74.00€5mg105.00€10mg156.00€25mg259.00€50mg378.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)113.00€M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurity:98.52%Color and Shape:SolidMolecular weight:508.62Ref: TM-T9689
1mg52.00€5mg116.00€10mg178.00€25mg306.00€50mg437.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)129.00€Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purity:99.76%Color and Shape:SolidMolecular weight:569.44Anti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Color and Shape:Odour LiquidPLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formula:C21H17F3N4Purity:99.38%Color and Shape:SolidMolecular weight:382.38Ref: TM-T1925
2mg42.00€5mg60.00€10mg90.00€25mg134.00€50mg188.00€100mg279.00€200mg411.00€1mL*10mM (DMSO)64.00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)92.00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurity:98.78% - 99.72%Color and Shape:White PowderMolecular weight:437.52Ref: TM-T0097L
10mg49.00€25mg73.00€50mg96.00€100mg145.00€200mg236.00€500mg331.00€1mL*10mM (DMSO)59.00€Anti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Color and Shape:Odour Liquid
