Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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BRD5631
CAS:BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.Formula:C30H35N3O4Purity:98%Color and Shape:SolidMolecular weight:501.62GDC-0349
CAS:GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formula:C24H32N6O3Purity:96.00% - 98.98%Color and Shape:SolidMolecular weight:452.55Ref: TM-T6510
2mg39.00€5mg66.00€10mg107.00€25mg215.00€50mg324.00€100mg462.00€500mgTo inquire1mL*10mM (DMSO)70.00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:100% - 98.11%Color and Shape:SolidMolecular weight:718.08Ref: TM-T1773
1g467.00€5mg40.00€10mg59.00€25mg87.00€50mg107.00€100mg140.00€200mg188.00€500mg313.00€1mL*10mM (DMSO)66.00€mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21kaempferide
CAS:kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formula:C16H12O6Purity:98.31% - 99.66%Color and Shape:SolidMolecular weight:300.26SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purity:97.98% - ≥95%Color and Shape:SolidMolecular weight:479.4Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purity:99.84%Color and Shape:White Crystalline PowderMolecular weight:468.58XCT790
CAS:XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formula:C23H13F9N4O3SPurity:99% - 99.74%Color and Shape:SolidMolecular weight:596.42Pregnenolone
CAS:Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Formula:C21H32O2Purity:100% - 99.5%Color and Shape:SolidMolecular weight:316.48Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity againstFormula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purity:98.56% - 99.05%Color and Shape:SolidMolecular weight:383.46Ref: TM-T2277
2mg35.00€5mg52.00€10mg78.00€25mg139.00€50mg225.00€100mg406.00€500mg920.00€1mL*10mM (DMSO)55.00€Lanatoside C
CAS:Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formula:C49H76O20Purity:100% - 99.8%Color and Shape:SolidMolecular weight:985.12Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formula:C31H37N5O3Purity:97.73% - 98.80%Color and Shape:SolidMolecular weight:527.66Ref: TM-T6277
1g562.00€5mg37.00€10mg55.00€25mg79.00€50mg92.00€100mg127.00€200mg225.00€500mg379.00€1mL*10mM (DMSO)44.00€QN523
CAS:QN523 has drug-like traits, kills cancer cells in vitro, effective in vivo against pancreatic cancer, works via autophagy.Formula:C14H10N4OPurity:97.26%Color and Shape:SolidMolecular weight:250.26Ref: TM-T64374
1mg35.00€5mg74.00€10mg105.00€25mg207.00€50mg325.00€100mg469.00€200mg650.00€1mL*10mM (DMSO)71.00€Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purity:98.91% - 99.49%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Tigecycline
CAS:Tigecycline (GAR-936), a broad-spectrum glycylcycline, disrupts protein synthesis by binding the 30S ribosomal subunit.Formula:C29H39N5O8Purity:100% - 99.94%Color and Shape:PowderMolecular weight:585.65Ref: TM-T1569
5mg38.00€10mg57.00€25mg79.00€50mg105.00€100mg168.00€200mg248.00€500mg418.00€1mL*10mM (DMSO)59.00€Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purity:94.54% - 98.1%Color and Shape:SolidMolecular weight:338.35QX77
CAS:QX77 is a chaperone-mediated autophagy (CMA) activator.Formula:C16H13ClN2O2Purity:98.21%Color and Shape:SolidMolecular weight:300.74Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formula:C24H25ClFN5O3Purity:97.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Ref: TM-T21312
5mg35.00€10mg51.00€25mg86.00€50mg115.00€100mg144.00€200mg177.00€500mg300.00€1mL*10mM (DMSO)52.00€
