Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Aceglutamide
CAS:Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.Formula:C7H12N2O4Purity:99.56% - 99.77%Color and Shape:SolidMolecular weight:188.18Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57Nortriptyline hydrochloride
CAS:Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.Formula:C19H22ClNPurity:100% - ≥95%Color and Shape:SolidMolecular weight:299.84MTP
CAS:MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Formula:C29H23F3N4O2Purity:98%Color and Shape:SolidMolecular weight:516.51GC7 Sulfate
CAS:GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formula:C8H22N4O4SPurity:100% - 99.85%Color and Shape:SolidMolecular weight:270.35Ref: TM-T6S1784
1mg37.00€5mg74.00€10mg97.00€25mg157.00€50mg224.00€100mg335.00€200mg497.00€1mL*10mM (DMSO)81.00€LYS01
CAS:LYS01 free base is a new lysosomal autophagy inhibitor.Formula:C23H23Cl2N5Purity:98.28%Color and Shape:SolidMolecular weight:440.37Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurity:98.36%Color and Shape:Yellow SolidMolecular weight:528.94Aliskiren hemifumarate
CAS:Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.Formula:C30H53N3O6C4H4O4Purity:96.18% - 99.21%Color and Shape:SolidMolecular weight:1219.6Zoledronic Acid
CAS:Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐,能抑制破骨细胞的分化和凋亡,具有高效的抗骨质再吸收活性,也有抗癌作用。Formula:C5H10N2O7P2Purity:98% - 99.93%Color and Shape:White Crystalline PowderMolecular weight:272.09GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:541.69Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormula:C7H8N4O2Purity:99.47% - 99.97%Color and Shape:White Solid PowderMolecular weight:180.16Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as a detergent to solubilize fats for intestinal absorption.Formula:C24H40O4Purity:99.70% - 99.72%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Monacolin J
CAS:Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formula:C19H28O4Purity:98.06%Color and Shape:SolidMolecular weight:320.42Ref: TM-T12092
1mg79.00€5mg160.00€10mg235.00€25mg398.00€50mg567.00€100mg820.00€1mL*10mM (DMSO)170.00€Purmorphamine
CAS:Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.Formula:C31H32N6O2Purity:97.19% - 99.48%Color and Shape:Light Tan SolidMolecular weight:520.62Glyphosate
CAS:Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.Formula:C3H8NO5PPurity:99.42% - 99.79%Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Molecular weight:169.07Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formula:C35H38Cl2N8O4Purity:98% - 99.90%Color and Shape:Off-White Crystalline SolidMolecular weight:705.63CZC-25146 hydrochloride
CAS:CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.Formula:C22H26ClFN6O4SPurity:98.76%Color and Shape:SolidMolecular weight:525CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formula:C14H17NO3Purity:99.75%Color and Shape:SolidMolecular weight:247.29Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formula:C30H48O3Purity:99.12% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.7
