Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Pantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormula:C16H14F2N3NaO4SH2OPurity:98.32%Color and Shape:SolidMolecular weight:432.37Di-N-desethyl amiodarone hydrochloride
CAS:Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formula:C21H22ClI2NO3Purity:98%Color and Shape:SolidMolecular weight:625.67Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.42% - 99%Color and Shape:SolidMolecular weight:344.32UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purity:99.82%Color and Shape:SolidMolecular weight:436.58Ref: TM-T17209
1mg35.00€2mg52.00€5mg74.00€10mg119.00€25mg243.00€50mg406.00€100mg607.00€1mL*10mM (DMSO)86.00€NDBM
NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screeningFormula:C33H35BrN4O7Purity:98%Color and Shape:SolidMolecular weight:679.56Magnolol
CAS:Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formula:C18H18O2Purity:99.49%Color and Shape:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaMolecular weight:266.33CUR5g
CAS:CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formula:C22H20N2O2Purity:98.92%Color and Shape:SolidMolecular weight:344.41Ref: TM-T73550
1mg92.00€5mg216.00€10mg344.00€25mg692.00€50mg1,103.00€100mg1,644.00€1mL*10mM (DMSO)240.00€ATG7-IN-1
CAS:ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.Formula:C17H19FN6O5S2Purity:100% - 100%Color and Shape:SolidMolecular weight:470.5BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Formula:C15H17ClFNO4SPurity:100% - 99.9%Color and Shape:SolidMolecular weight:361.82Ref: TM-TQ0181
1mg49.00€2mg70.00€5mg96.00€10mg164.00€25mg306.00€50mg502.00€100mg805.00€1mL*10mM (DMSO)116.00€Polydatin
CAS:Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.Formula:C20H22O8Purity:97.2% - 98.83%Color and Shape:White Fine PowderMolecular weight:390.38LC3-mHTT-IN-AN2
CAS:LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formula:C15H10O4Purity:≥98%Color and Shape:SolidMolecular weight:254.24Clemastine fumarate
CAS:Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.Formula:C25H30ClNO5Purity:99.52% - 99.8%Color and Shape:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderMolecular weight:459.97Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.Formula:C18H22BrN5O3Purity:98.86% - 99.63%Color and Shape:SolidMolecular weight:436.3Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88Ref: TM-T10990
1mg58.00€5mg111.00€10mg160.00€25mg264.00€50mg396.00€100mg563.00€1mL*10mM (DMSO)124.00€ATG16L1 stabilizer-1
ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent stabilizer of ATG16L1 that enhances cellular autophagy (Autophagy). Regardless of the presence of FKBP12, it has an inhibitory EC50 value of 12.1 μM for ATG16L1. When used alone, ATG16L1 stabilizer-1 can induce GFP-LC3 puncta formation, with an EC50 value of 12.0 μM.Formula:C45H62N14O5SColor and Shape:SolidMolecular weight:911.13Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:100% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:1030.29Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47Ref: TM-T6055
1mg59.00€2mg86.00€5mg124.00€10mg213.00€25mg331.00€50mg427.00€100mg607.00€1mL*10mM (DMSO)139.00€Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26
