Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purity:96.92% - 98.03%Color and Shape:Crystalline SolidMolecular weight:422.49(-)-Epicatechin gallate
CAS:(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formula:C22H18O10Purity:96.65% - 99.72%Color and Shape:SolidMolecular weight:442.37ATG12-IN-1
CAS:ATG12-IN-1 (compound 4) acts as an autophagy inhibitor targeting the ATG12-ATG3 protein-protein interaction (IC50= 9 μM), suitable for research in cancer studies.Formula:C23H15ClN4O2Color and Shape:SolidMolecular weight:414.84BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purity:98.19%Color and Shape:SolidMolecular weight:548.34Ref: TM-T10591
1mg47.00€5mg117.00€10mg170.00€25mg280.00€50mg409.00€100mg565.00€200mg758.00€1mL*10mM (DMSO)135.00€Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formula:C15H10O7Purity:96.29% - 98.05%Color and Shape:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Molecular weight:302.24Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Ref: TM-T2500
2mg42.00€5mg63.00€10mg92.00€25mg136.00€50mg177.00€100mg254.00€200mg462.00€500mg742.00€1mL*10mM (DMSO)69.00€Ursolic acid
CAS:Ursolic acid (Prunol) is a natural pentacyclic triterpene carboxylic acid. Ursolic acid has anti-tumor and anti-inflammatory effects. Cost-effective and quality-assured.Formula:C30H48O3Purity:99.66% - 99.79%Color and Shape:Platelets From Alcohol SolidMolecular weight:456.7LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.78% - 99.76%Color and Shape:SolidMolecular weight:402.39Ref: TM-T2834
5mg57.00€10mg88.00€25mg124.00€50mg168.00€100mg265.00€200mg393.00€500mg653.00€1mL*10mM (DMSO)59.00€Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Formula:C19H23NO4Purity:99.02% - 99.89%Color and Shape:White PowderMolecular weight:329.39Sulfosuccinimidyl oleate
CAS:Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formula:C22H37NO7SPurity:98%Color and Shape:SolidMolecular weight:459.6Tubastatin A
CAS:Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formula:C20H21N3O2Purity:97.22% - 99.51%Color and Shape:SolidMolecular weight:335.4Ref: TM-T1966
10mg48.00€25mg64.00€50mg79.00€100mg111.00€200mg169.00€500mg274.00€1mL*10mM (DMSO)47.00€N-Benzylpalmitamide
CAS:N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFormula:C23H39NOPurity:97.08% - 99.77%Color and Shape:SolidMolecular weight:345.56LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formula:C23H26O3Purity:98.65%Color and Shape:SolidMolecular weight:350.45Ref: TM-T11844
2mg47.00€5mg70.00€10mg97.00€25mg167.00€50mg249.00€100mg369.00€200mg545.00€1mL*10mM (DMSO)77.00€Icaritin
CAS:Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formula:C21H20O6Purity:97.69% - 98.96%Color and Shape:SolidMolecular weight:368.38EAD1
CAS:EAD1 is a useful organic compound for research related to life sciences. The catalog number is T35329 and the CAS number is 1644388-26-0.Formula:C24H27Cl2N7Purity:98%Color and Shape:SolidMolecular weight:484.42R1487 Hydrochloride
CAS:R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.Formula:C19H19ClF2N4O3Purity:99.42%Color and Shape:SolidMolecular weight:424.834E2RCat
CAS:4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expressionFormula:C22H14ClNO4S2Purity:96.48%Color and Shape:SolidMolecular weight:455.93Onjisaponin B
CAS:Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-Formula:C75H112O35Purity:99.20% - 99.88%Color and Shape:SolidMolecular weight:1573.67Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formula:C10H19N2O5PPurity:99.87% - ≥95%Color and Shape:SolidMolecular weight:278.24Ref: TM-T6641
1mg40.00€5mg88.00€10mg137.00€25mg264.00€50mg418.00€100mg627.00€500mg1,301.00€1mL*10mM (DMSO)87.00€
