DUB
DUB inhibitors target deubiquitinases, enzymes that remove ubiquitin molecules from proteins, thereby regulating the stability, localization, and activity of proteins within the cell. Deubiquitinases play essential roles in various cellular processes, including cell cycle regulation, DNA repair, and immune responses. Dysregulation of DUB activity is linked to cancer, neurodegenerative disorders, and viral infections. Inhibitors of DUBs can modulate these processes, offering potential therapeutic approaches for these conditions. At CymitQuimica, we provide DUB inhibitors to support your research in protein homeostasis, cancer, and neurobiology.
Products of "DUB"
Sort by
OTUB1/USP8-IN-1
CAS:OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.Formula:C22H16ClFN2O4Purity:98.59%Color and Shape:SoildMolecular weight:426.83USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Formula:C18H11Cl2N3O3S3Purity:97.98% - 98.5%Color and Shape:SolidMolecular weight:484.4Ref: TM-T4338
1mg43.00€5mg92.00€10mg160.00€25mg329.00€50mg547.00€100mg905.00€500mg1,786.00€1mL*10mM (DMSO)99.00€FT671
CAS:FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).Formula:C24H23F4N7O3Purity:98%Color and Shape:SolidMolecular weight:533.48USP25/28 inhibitor AZ1
CAS:USP25/28 inhibitor AZ1 is a selective, orally active and non-competitive dual ubiquitin-specific protease USP25/28 inhibitor.Cost-effective and quality-assured.Formula:C17H16BrF4NO2Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:422.21Ref: TM-T7685
1mg35.00€5mg70.00€10mg97.00€25mg210.00€50mg321.00€100mg472.00€500mg1,035.00€1mL*10mM (DMSO)78.00€SJB3-019A
CAS:SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 timesFormula:C16H8N2O3Purity:99.75%Color and Shape:SolidMolecular weight:276.25Ref: TM-T12926
1mg94.00€2mg137.00€5mg224.00€10mg339.00€25mg560.00€50mg810.00€100mg1,121.00€500mg2,232.00€IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。Formula:C18H21FN2OPurity:98% - 99.30%Color and Shape:SolidMolecular weight:300.37LDN-91946
CAS:LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).Formula:C15H10N2O4SPurity:92.78%Color and Shape:SolidMolecular weight:314.32GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Formula:C20H18N4OPurity:98.64%Color and Shape:SolidMolecular weight:330.38Ref: TM-T5461
1mg70.00€2mg92.00€5mg153.00€10mg250.00€25mg535.00€50mg772.00€100mg1,074.00€1mL*10mM (DMSO)166.00€GSK2643943A
CAS:GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.Formula:C17H12FN3Purity:97.09%Color and Shape:SolidMolecular weight:277.3USP28-IN-4
CAS:USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Formula:C22H18Cl2N2O3SPurity:98.48%Color and Shape:SolidMolecular weight:461.36USP7-IN-6
CAS:USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).Formula:C41H43N7O4SPurity:98%Color and Shape:SolidMolecular weight:729.89USP8-IN-3
CAS:USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D.Formula:C18H18F3N5O2SPurity:99.18%Color and Shape:SolidMolecular weight:425.43Ref: TM-T67873
1mg35.00€5mg64.00€10mg97.00€25mg207.00€50mg329.00€100mg475.00€500mg938.00€1mL*10mM (DMSO)84.00€P22074
CAS:P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.Formula:C12H9NO3S2Purity:100%Color and Shape:SolidMolecular weight:279.33ML364
CAS:ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.Formula:C24H18F3N3O3S2Purity:100% - 99.92%Color and Shape:SolidMolecular weight:517.54
