Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Products of "Endothelin Receptor"
Sort by
Sulfatroxazole
CAS:Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.Formula:C11H13N3O3SColor and Shape:SolidMolecular weight:267.3Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Formula:C32H40N4O5SPurity:97.94% - 98.75%Color and Shape:SolidMolecular weight:592.75Ref: TM-T5355
2mg39.00€5mg58.00€10mg94.00€25mg170.00€50mg259.00€100mg380.00€200mg540.00€1mL*10mM (DMSO)77.00€Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Formula:C27H29N5O6S·H2OPurity:99.31% - 99.86%Color and Shape:White PowderMolecular weight:569.63Myriceric acid C
CAS:Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma.Formula:C48H60O10Purity:98%Color and Shape:SolidMolecular weight:796.98BMS 182874 hydrochloride
CAS:BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.Formula:C17H20ClN3O3SPurity:97.01%Color and Shape:SolidMolecular weight:381.88Ref: TM-T21790
1mg81.00€2mg97.00€5mg148.00€10mg215.00€25mg361.00€50mg505.00€100mg702.00€200mg947.00€1mL*10mM (DMSO)155.00€BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purity:98.67%Color and Shape:SolidMolecular weight:641.8Ref: TM-T10595
1mg137.00€2mg188.00€5mg329.00€10mg472.00€25mg753.00€50mg1,017.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)360.00€RO 46-8443
CAS:RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.Formula:C31H35N3O8SPurity:98.77% - 99.77%Color and Shape:SolidMolecular weight:609.69Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurity:97.00% - 99.34%Color and Shape:SolidMolecular weight:424.43Avosentan
CAS:Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.Formula:C23H21N5O5SPurity:98.25% - 99.47%Color and Shape:SolidMolecular weight:479.51BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2Formula:C96H140N20O25S·xNH3Purity:98%Color and Shape:SolidMolecular weight:2006.32 (free base)Enrasentan
CAS:Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.Formula:C29H30O8Purity:97.90% - 97.96%Color and Shape:SolidMolecular weight:506.54
