DHFR
Dihydrofolate reductase (DHFR) is an enzyme that plays a crucial role in the folate cycle, which is essential for DNA synthesis, repair, and methylation. DHFR inhibitors are widely used as chemotherapeutic agents in the treatment of cancer and autoimmune diseases due to their ability to inhibit cell proliferation. At CymitQuimica, we provide a variety of DHFR inhibitors to support your research in cancer therapy, immunology, and molecular biology.
Products of "DHFR"
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P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Formula:C18H25ClN4O4Purity:99.50%Color and Shape:SoildMolecular weight:396.87Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purity:99.13%Color and Shape:SolidMolecular weight:349.34Ref: TM-T37655
1mg78.00€5mg169.00€10mg250.00€25mg432.00€50mg628.00€100mg905.00€1mL*10mM (DMSO)178.00€Methotrexate Diglutamate
CAS:Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.Formula:C25H29N9O8Purity:98.84%Color and Shape:SolidMolecular weight:583.55Brodimoprim
CAS:Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).Formula:C13H15BrN4O2Purity:98% - 98.33%Color and Shape:SolidMolecular weight:339.19Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Formula:C12H13ClN4Purity:99.67%Color and Shape:CrystalsMolecular weight:248.71Sulfameter
CAS:Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.Formula:C11H12N4O3SPurity:99.46% - 99.90%Color and Shape:Crystalline SolidMolecular weight:280.3Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formula:C20H21N5O6Purity:98.1% - 99.92%Color and Shape:Similar To White PowderMolecular weight:427.41DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formula:C28H31F3N4O6SPurity:98.27% - 99.63%Color and Shape:SolidMolecular weight:608.63Ref: TM-T11103
1mg115.00€5mg274.00€10mg432.00€25mg777.00€50mg1,264.00€100mg1,700.00€1mL*10mM (DMSO)378.00€
