PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
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Anti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Color and Shape:Odour LiquidTMBIM6 antagonist-1
CAS:TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitorFormula:C15H12N2O3Purity:99.26%Color and Shape:SolidMolecular weight:268.27Ref: TM-T8649
1mg93.00€2mg120.00€5mg187.00€10mg315.00€25mg567.00€50mg810.00€100mg1,111.00€500mg2,232.00€1mL*10mM (DMSO)202.00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purity:97.72% - 99.75%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1741
1mg43.00€2mg56.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg429.00€1mL*10mM (DMSO)63.00€GSK-3 inhibitor 1
CAS:GSK-3 inhibitor 1 is a GSK-3 inhibitor.Formula:C22H17ClFN5O2Purity:98.11%Color and Shape:SolidMolecular weight:437.85Ref: TM-T11468
1mg104.00€5mg216.00€10mg354.00€25mg677.00€50mg1,008.00€100mg1,491.00€1mL*10mM (DMSO)240.00€Calotatug ginistinag
CAS:Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate (ADC) aimed at targeting HER2. It is connected by a linker (XMT-1519 conjugate-1) to an effective payload that includes a STING agonist (STING agonist-20), presenting potential in immune activation and anti-tumor activity.Color and Shape:LiquidEGFR vIII Protein, Human, Recombinant (hFc)
EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Color and Shape:Lyophilized PowderMolecular weight:90-120 KDa (reducing condition)EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Formula:C18H14FN5O2SPurity:98.27%Color and Shape:SolidMolecular weight:383.4PS47
CAS:PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.Formula:C17H15ClO2Purity:99.09%Color and Shape:SolidMolecular weight:286.75Ref: TM-T24677
5mg46.00€10mg65.00€25mg123.00€50mg187.00€100mg309.00€200mg435.00€1mL*10mM (DMSO)65.00€GSK-3 inhibitor 3
CAS:GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectivelyFormula:C23H15FN6OPurity:98.36%Color and Shape:SoildMolecular weight:410.4MHY-1685
CAS:MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.Formula:C11H8N2O4Purity:98.44%Color and Shape:SolidMolecular weight:232.19SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurity:99.80% - ≥98%Color and Shape:SolidMolecular weight:380.25Ref: TM-T7362
1mg66.00€2mg96.00€5mg144.00€10mg216.00€25mg432.00€50mg638.00€100mg908.00€500mg1,825.00€1mL*10mM (DMSO)159.00€NS-062
CAS:NS-062 is an orally effective, irreversible covalent inhibitor targeting EGFR, demonstrating antiproliferative activity in the resistant double mutant H1975 cells with an IC50 of 0.19 μM. It also exhibits antitumor activity in a murine H1975 xenograft model.Formula:C28H30Cl2F2N6O4Color and Shape:SolidMolecular weight:623.48A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurity:97.52% - 99.58%Color and Shape:SolidMolecular weight:360.39Ref: TM-T2468
2mg39.00€5mg57.00€10mg79.00€25mg142.00€50mg256.00€100mg465.00€500mg1,017.00€1mL*10mM (DMSO)59.00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purity:99.17%Color and Shape:SolidMolecular weight:547.965-Bromo-3-indoxylacetate
CAS:5-Bromo-3-indoxylacetate acts as an inhibitor of GSK-3, with a pIC50 value of 3.39.Formula:C10H8BrNO2Color and Shape:SolidMolecular weight:254.08MELK-8a Dihydrochloride
MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T35342.Purity:98%Color and Shape:SolidDNA-PK-IN-10
CAS:DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].Formula:C25H28N6O2Purity:98%Color and Shape:SolidMolecular weight:444.53CP-724714
CAS:CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2Formula:C27H27N5O3Purity:97.10% - 98.82%Color and Shape:SolidMolecular weight:469.54Ref: TM-T4014
1mg44.00€2mg58.00€5mg95.00€10mg157.00€25mg273.00€50mg454.00€100mg660.00€1mL*10mM (DMSO)89.00€EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Formula:C19H15N3O2SPurity:100%Color and Shape:SolidMolecular weight:349.41Anti-EGFR Monoclonal Antibody-APC
Anti-EGFR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EGFR. Anti-EGFR Monoclonal Antibody-APC can be used in FACS.Purity:> 95% as determined by SDS-PAGE.Color and Shape:LiquidMolecular weight:150 kDaPI3K-IN-41
PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K inhibition following UV lightFormula:C45H39F2N5O12SPurity:98%Color and Shape:SolidMolecular weight:911.88PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:95.65% - 98%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg47.00€5mg69.00€10mg116.00€25mg188.00€50mg321.00€100mg510.00€200mg725.00€1mL*10mM (DMSO)74.00€Cyasterone
CAS:Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormula:C29H44O8Purity:99.32% - 99.70%Color and Shape:SolidMolecular weight:520.65Olafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Formula:C29H28F2N6O2Purity:98.43%Color and Shape:SolidMolecular weight:530.57CC214-1
CAS:CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in vitro tool compound for exploring the biology of mTOR kinases.Formula:C20H21N7O2Purity:97.87%Color and Shape:SolidMolecular weight:391.43TG 100713
CAS:TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.Formula:C12H10N6OPurity:98.17%Color and Shape:SolidMolecular weight:254.25Eganelisib
CAS:Eganelisib (IPI-549) is an inhibitor of PI3Kγ (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively)Formula:C30H24N8O2Purity:99.04% - 99.28%Color and Shape:SolidMolecular weight:528.56Tyrphostin AG 879
CAS:Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Formula:C18H24N2OSPurity:99.05%Color and Shape:SolidMolecular weight:316.46TDZD-8
CAS:TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.Formula:C10H10N2O2SPurity:97.13% - 99.48%Color and Shape:White SolidMolecular weight:222.26Gedatolisib
CAS:Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signalingFormula:C32H41N9O4Purity:98% - 99.48%Color and Shape:SolidMolecular weight:615.73EGFR-IN-7
CAS:EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.Formula:C32H41BrN9O2PPurity:95.32% - 99.64%Color and Shape:SolidMolecular weight:694.6GDC-0349
CAS:GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formula:C24H32N6O3Purity:96.00% - 98.98%Color and Shape:SolidMolecular weight:452.55Ref: TM-T6510
2mg39.00€5mg66.00€10mg107.00€25mg215.00€50mg324.00€100mg462.00€500mgTo inquire1mL*10mM (DMSO)70.00€Serabelisib
CAS:Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).Formula:C19H17N5O3Purity:98.41% - 99.5%Color and Shape:SolidMolecular weight:363.37Ref: TM-T3153
1mg44.00€2mg58.00€5mg92.00€10mg115.00€25mg225.00€50mg329.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)92.00€PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Color and Shape:SolidMolecular weight:426.853lavendustin A
CAS:lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.Formula:C21H19NO6Purity:98%Color and Shape:Off-White SolidMolecular weight:381.389-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purity:99.32%Color and Shape:SolidMolecular weight:404.35Ref: TM-T14066
1mg49.00€2mg70.00€5mg99.00€10mg163.00€25mg325.00€50mg472.00€100mg705.00€1mL*10mM (DMSO)116.00€Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5FT-1518
CAS:FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.Formula:C20H26N8OPurity:98.34% - 98.80%Color and Shape:SolidMolecular weight:394.47RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Formula:C14H8Cl2N2Purity:99.56% - 99.82%Color and Shape:SolidMolecular weight:275.13Ref: TM-T3554
2mg35.00€5mg52.00€10mg77.00€25mg137.00€50mg259.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)58.00€mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21BpV(HOpic)
CAS:BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).Formula:C6H4K2NO8VPurity:99.86%Color and Shape:SolidMolecular weight:347.24CC-115
CAS:CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).Formula:C16H16N8OPurity:86.79% - 99.22%Color and Shape:SolidMolecular weight:336.35PITCOIN4
PITCOIN4 is a Class II Alpha PI3K-C2α inhibitor with high selectivity, demonstrating nanomolar inhibition of PI3K-C2α and exhibiting over 100-fold selectivityPurity:98%Color and Shape:Odour SolidBLU-945
CAS:BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.Formula:C28H37FN6O3SPurity:99.11% - 99.16%Color and Shape:SolidMolecular weight:556.7XMD-17-51 Trifluoroacetate
CAS:XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound that regulates protein kinases.Formula:C23H25F3N8O3Purity:99.65%Color and Shape:SolidMolecular weight:518.49Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purity:99.56% - 99.56%Color and Shape:White SolidMolecular weight:571.55Ref: TM-T4976
1mg48.00€2mg65.00€5mg96.00€10mg170.00€25mg343.00€50mg449.00€100mg658.00€1mL*10mM (DMSO)120.00€1,5-Dihydroxyxanthone
CAS:1,5-Dihydroxyxanthone inhibits EGFR-tyrosine kinase (IC50: 90.34 nM) and may block AChE/BChE.Formula:C13H8O4Purity:98%Color and Shape:SolidMolecular weight:228.203DA-0157
CAS:DA-0157 is an orally active inhibitor targeting EGFR and ALK, designed to overcome resistance mutations in non-small cell lung cancer (NSCLC). It effectively inhibits the proliferation of Ba/F3-EGFR Del19/T790M/C797S (IC50= 6.9 nM), Ba/F3-EGFR WT (IC50= 0.83 μM), Ba/F3-EML4-ALK-L1196M (IC50= 5.5 nM), and Ba/F3-EML4-ALK (IC50= 7.4 nM). Additionally, DA-0157 inhibits CYP2D6 with an IC50 of 5.26 μM and demonstrates antitumor activity in mouse models.Formula:C31H43BrN7O2PColor and Shape:SolidMolecular weight:656.597EGFR/HER2/DHFR-IN-3
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.Purity:98%Color and Shape:Odour SolidIBI-334
IBI-334 is a bispecific antibody targeting both B7-H3 and EGFR. It features an EGFR arm responsible for signal blocking, connected to a modified B7-H3 arm that ensures optimal affinity and binding. The antibody is afucosylated to enhance its antibody-dependent cellular cytotoxicity (ADCC) effects. IBI-334 is widely applicable in EGFR-driven solid tumors.Color and Shape:Odour LiquidRTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Formula:C24H22ClF3N2O3SPurity:98.14%Color and Shape:SolidMolecular weight:510.96Ref: TM-T12777
5mg52.00€10mg80.00€25mg169.00€50mg284.00€100mg411.00€500mg867.00€1mL*10mM (DMSO)59.00€LAS191954
CAS:LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).Formula:C20H15N9OPurity:98%Color and Shape:SolidMolecular weight:397.39Gefitinib hydrochloride
CAS:Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.Formula:C22H25Cl2FN4O3Purity:99.8%Color and Shape:SolidMolecular weight:483.36D-106669
CAS:D-106669 (comppun 150) is a potent inhibitor of PI3Kα, with an IC50 value of 0.129 μM, and plays a significant role in cancer research.Formula:C17H18N6OColor and Shape:SolidMolecular weight:322.36EGFR-IN-99
CAS:EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).Formula:C25H22FN7O3Purity:97.75%Color and Shape:SolidMolecular weight:487.49SOS1/EGFR-IN-2
SOS1/EGFR-IN-2 (Compound 4) functions as a dual inhibitor of SOS1 and EGFR, exhibiting IC50 values of 8.3 and 14.6 nM, respectively. It demonstrates significant antiproliferative effects on cancer cells harboring various KRAS mutations.Formula:C25H29F3N4O3Color and Shape:SolidMolecular weight:490.52(E/Z)-GSK-3β inhibitor 1
CAS:(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurity:98.60%Color and Shape:SolidMolecular weight:222.24Ref: TM-T9178
1mg38.00€5mg85.00€10mg126.00€25mg225.00€50mg335.00€100mg480.00€200mg652.00€1mL*10mM (DMSO)94.00€Cetuximab
CAS:Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).Formula:C107H179N35O36S7Purity:100.00% - SDS-PAGE:98.4%；SEC-HPLC: 99.7%Color and Shape:LiquidMolecular weight:152 kDaPD-149163 hydrochloride
PD-149163 hydrochloride is a neurokinin B agonist with antipsychotic activity, used for research on neurological diseases.Formula:C42H72ClN9O6Color and Shape:SolidMolecular weight:834.53NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.68Ref: TM-T16355
2mg42.00€5mg64.00€10mg93.00€25mg168.00€50mg245.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)88.00€Azerutamig
Azerutamig is a dual-specificity antibody targeting KLRK1/ERBB2 of type (H-γ1_L-κ)_scFvkh-H-γ1(h-CH2-CH3).Color and Shape:Odour LiquidSTL127705
CAS:STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.Formula:C22H20FN5O4Purity:97.41% - 99.18%Color and Shape:SolidMolecular weight:437.42Ref: TM-T13017
1mg114.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€500mg2,717.00€1mL*10mM (DMSO)316.00€Mutated EGFR-IN-1
CAS:Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activatingFormula:C25H31N7OPurity:98.91%Color and Shape:SolidMolecular weight:445.56OTSSP167 hydrochloride
CAS:OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).Formula:C25H29Cl3N4O2Purity:99.41%Color and Shape:SolidMolecular weight:523.88Ref: TM-T21559
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€1mL*10mM (DMSO)92.00€PI3K-IN-9
CAS:PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).Formula:C19H23N7OPurity:98%Color and Shape:SolidMolecular weight:365.43HTH-02-006
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells and inhibits YAP-driven cell proliferation, hepatomegaly,Formula:C25H29IN6O3Purity:98%Color and Shape:SoildMolecular weight:588.45PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurity:98.88%Color and Shape:SolidMolecular weight:371.23Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purity:98.01% - 99.19%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ref: TM-TL0016
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg227.00€50mg338.00€100mg500.00€1mL*10mM (DMSO)69.00€Losatuxizumab
CAS:Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.Purity:95% - 95%Color and Shape:LiquidTenalisib
CAS:Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)Formula:C23H18FN5O2Purity:99.71%Color and Shape:SolidMolecular weight:415.42Ref: TM-T13119
1mg38.00€2mg49.00€5mg81.00€10mg111.00€25mg188.00€50mg304.00€100mg457.00€1mL*10mM (DMSO)88.00€YKL-05-099
CAS:YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 and SIK3.Cost-effective and quality-assured.Formula:C32H34ClN7O3Purity:99.57% - 99.66%Color and Shape:SolidMolecular weight:600.11Ref: TM-T17271
1mg74.00€5mg120.00€10mg180.00€25mg311.00€50mg464.00€100mg655.00€1mL*10mM (DMSO)159.00€Nimotuzumab
CAS:Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).Purity:95.00%Color and Shape:Liquid8-Chloroadenosine
CAS:8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.Formula:C10H12ClN5O4Purity:98.75% - 99.48%Color and Shape:SolidMolecular weight:301.69Ref: TM-T19661
1mg35.00€5mg120.00€10mg188.00€25mg330.00€50mg494.00€100mg702.00€500mg1,406.00€1mL*10mM (DMSO)166.00€Mutated EGFR-IN-2
CAS:Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.Formula:C29H35FN8O3Purity:98%Color and Shape:SolidMolecular weight:562.64Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purity:98.31% - ≥95%Color and Shape:Solid PowderMolecular weight:495.02Ref: TM-T3506
1mg37.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)87.00€WZ8040
CAS:WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Formula:C24H25ClN6OSPurity:97.42%Color and Shape:SolidMolecular weight:481.01EGFR mutant-IN-1
EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening EGFRWT impact.Formula:C34H39ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:632.17BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purity:99.08%Color and Shape:SolidMolecular weight:368.43Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:100% - 99.85%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg43.00€2mg56.00€5mg88.00€10mg106.00€25mg213.00€50mg344.00€100mg550.00€1mL*10mM (DMSO)87.00€Astragaloside VI
CAS:Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.Formula:C47H78O19Purity:98%Color and Shape:SolidMolecular weight:947.122Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.69%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.GSK2292767
CAS:GSK2292767 is a potent and selective PI3Kδ inhibitor.Formula:C24H28N6O5SPurity:98%Color and Shape:SolidMolecular weight:512.58YK-029A
CAS:YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.Formula:C27H32N8O2Purity:98%Color and Shape:SolidMolecular weight:500.6PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21CAL-130 Racemate
CAS:CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurity:98%Color and Shape:SolidMolecular weight:426.47GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formula:C15H12N4O2SColor and Shape:SolidMolecular weight:312.35WAY-270360
CAS:WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.Formula:C22H19N3O3Purity:98.66%Color and Shape:SolidMolecular weight:373.4Rostafuroxin
CAS:Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.Formula:C23H34O4Purity:100% - 99.08%Color and Shape:SolidMolecular weight:374.51PI3K-IN-6
CAS:PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).Formula:C17H14Cl2FN9OPurity:98%Color and Shape:SolidMolecular weight:450.26TG100-115
CAS:TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.Formula:C18H14N6O2Purity:100% - 98.95%Color and Shape:SolidMolecular weight:346.34Ref: TM-T2672
1mg43.00€5mg85.00€10mg115.00€25mg210.00€50mg378.00€100mg588.00€500mg1,216.00€1mL*10mM (DMSO)92.00€Protopine hydrochloride
CAS:Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.Formula:C20H20ClNO5Purity:98%Color and Shape:Prisms From Alc SolidMolecular weight:389.83MARK4 inhibitor 2
MARK4 Inhibitor 2 is a potent inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4), exhibiting a Kₘ of 6.3×10⁷ and an IC₅₀ of 0.82 μM.Formula:C34H30N4O3Purity:98%Color and Shape:SolidMolecular weight:542.63EGFR/HER2/DHFR-IN-2
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively.Purity:98%Color and Shape:Odour SolidErucic acid
CAS:Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ).Formula:C22H42O2Purity:99.64%Color and Shape:Needles From Alcohol Liquid OthersolidMolecular weight:338.57PI3Kα/mTOR-IN-1
CAS:PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR.Formula:C16H18N6OPurity:99.3%Color and Shape:SolidMolecular weight:310.35GSK-3β inhibitor 26
CAS:GSK-3β inhibitor26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. This compound is applicable in research related to cancer, inflammation, and neurodegenerative diseases.Formula:C15H11N3O3Color and Shape:SolidMolecular weight:281.266PI-3065
CAS:PI-3065 is a novel potent and selective PI3K p110δ inhibitor.Formula:C27H31FN6OSPurity:98.39% - ≥95%Color and Shape:SolidMolecular weight:506.64
